scholarly journals Silent brain infarct is independently associated with arterial stiffness indicated by cardio-ankle vascular index (CAVI)

2012 ◽  
Vol 35 (7) ◽  
pp. 756-760 ◽  
Author(s):  
Naoki Saji ◽  
Kazumi Kimura ◽  
Hirotaka Shimizu ◽  
Yasushi Kita
Keyword(s):  
Arterial Stiffness ◽  
Brain Infarct ◽  
Silent Brain Infarct

Silent Brain Infarct After Carotid Artery Surgery: Incidence and Prevention

1995 ◽  
Vol 9 ◽  
pp. S76-S80 ◽  
Author(s):  
Yves Alimi ◽  
Koobhiraj Kallee ◽  
Martine Poncet ◽  
Didier Fabre ◽  
Christophe Doddoli ◽  
...  
Keyword(s):  
Carotid Artery ◽  
Brain Infarct ◽  
Carotid Artery Surgery ◽  
Silent Brain Infarct ◽  
Surgery Incidence

The silent brain infarct in carotid surgery

1986 ◽  
Vol 3 (3) ◽  
pp. 442-447 ◽  
Author(s):  
Ramon Berguer ◽  
Mary Y. Sieggreen ◽  
Alfredo Lazo ◽  
George T. Hodakowski
Keyword(s):  
Carotid Surgery ◽  
Brain Infarct ◽  
Silent Brain Infarct

Asymptomatic carotid stenosis and concomitant silent brain infarctions

Vascular ◽  
2019 ◽  
Vol 28 (1) ◽  
pp. 7-15 ◽  
Author(s):  
Claudina Rudolph ◽  
Nikolaj Eldrup
Keyword(s):  
Carotid Stenosis ◽  
Diagnostic Criteria ◽  
Significant Risk ◽  
Significant Risk Factor ◽  
Current Evidence ◽  
Asymptomatic Carotid Stenosis ◽  
Brain Infarct ◽  
Asymptomatic Carotid ◽  
Silent Brain Infarct ◽  
Increased Risk

Objectives This review aims to clarify (1) the definition of silent brain infarct (SBI), (2) the diagnostic criteria of SBI using magnetic resonance imaging (MRI), (3) the prevalence of patients with asymptomatic carotid stenosis and SBI based on MRI assessment, (4) the association of SBI and asymptomatic carotid stenosis and the risk of stroke compared to patients without SBI, (5) the association between development of dementia/cognitive impairment in people with asymptomatic carotid stenosis and SBI, and (6) the evidence for treating patients with carotid stenosis and SBI. Methods A systematic search of PubMed and Scopus including all studies published from 2000 to 2018 and written in English. Results No consensus of the definition and diagnostic criteria for SBI was found. The prevalence of SBI in asymptomatic carotid patients is 17–33.3%. SBI is a significant risk factor for future stroke, OR 4.6 (95% CI: 3.0–7.2; p < 0.0001). One substudy showed that immediate CEA is beneficial compared to delayed CEA in these patients, showing a 45% reduction in annual stroke rate from 1.5%/year to 0.7%/year. Conclusion This review emphasizes the need to standardize the definition and diagnostic criteria of SBI on MRI. Current evidence suggests an increased risk and a small potential benefit of offering carotid endarterectomy to patient with silent brain infarct. Prospective studies are warranted to elucidate these issues further.

scholarly journals Visceral adiposity index is associated with silent brain infarct in a healthy population

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Ki-Woong Nam ◽  
Hyung-Min Kwon ◽  
Han-Yeong Jeong ◽  
Jin-Ho Park ◽  
Hyuktae Kwon ◽  
...  
Keyword(s):  
Metabolic Diseases ◽  
Multivariable Analysis ◽  
Visceral Adiposity ◽  
Visceral Adiposity Index ◽  
Healthy Population ◽  
Consecutive Series ◽  
Limited Information ◽  
Brain Infarct ◽  
Adiposity Index ◽  
Silent Brain Infarct

Abstract Visceral adiposity index (VAI) has been associated with various cardio-metabolic diseases; however, there is limited information about its association with cerebrovascular diseases. In this study, we evaluated the relationship between VAI and silent brain infarct (SBI). We evaluated a consecutive series of healthy volunteers over the age of 40 between January 2006 and December 2013. SBI was defined as an asymptomatic, well-defined lesion with a diameter ≥ 3 mm with the same signal characteristics as the cerebrospinal fluid. VAI was calculated using sex-specific equations as described in previous studies. A total of 2596 subjects were evaluated, and SBI was found in 218 (8%) participants. In multivariable analysis, VAI (adjusted odds ratio [aOR] = 1.30; 95% confidence interval [CI] 1.03–1.66; P = 0.030) remained a significant predictor of SBI after adjustment for confounders. The close relationship between VAI and SBI was prominent only in females (aOR = 1.44; 95% CI 1.00–2.07; P = 0.048). In the evaluation between VAI and the burden of SBI, VAI showed a positive dose–response relationship with the number of SBI lesions (P for trend = 0.037). High VAI was associated with a higher prevalence and burden of SBI in a neurologically healthy population.

Abstract TP204: Intima-Media Thickness in the Carotid Bifurcation, But Not Cardio-Ankle Vascular Index or Ankle-Brachial Index, is Related to Silent Brain Infarct on Magnetic Resonance Imaging in Healthy, Middle-Aged Japanese Individuals

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Yasuhiro Nishiyama ◽  
Toshiaki Otsuka ◽  
Kanako Muraga ◽  
Kazumi Kimura
Keyword(s):  
Carotid Artery ◽  
Ankle Brachial Index ◽  
Intima Media Thickness ◽  
Carotid Bifurcation ◽  
Resonance Imaging ◽  
Middle Aged ◽  
Brain Infarct ◽  
Carotid Ultrasonography ◽  
Media Thickness ◽  
Silent Brain Infarct

Background: Carotid ultrasonography is currently the principal noninvasive tool for evaluating subclinical atherosclerosis and carotid artery disease. Increased carotid intima-media thickness (IMT) may precede the development of atherosclerotic plaques. Several studies have shown that increased IMT is associated with increased incidence of stroke. Silent brain infarct (SBI) has been proposed as a strong subclinical risk marker for future symptomatic stroke onset. However, the relationship between SBI and elevated IMT in healthy, middle-aged Japanese individuals has not been adequately examined. Methods: We examined 280 Japanese adults (92 women; mean age, 52.9 ± 5 years) with no history of cardiocerebrovascular disease. We assessed all participants’ periventricular hyperintensities, deep subcortical white matter hyperintensities, SBI on magnetic resonance imaging, cardio-ankle vascular index (CAVI)/ankle-brachial index (ABI), and various vascular risk factors. In addition, we measured intima-media thickness at the common carotid artery (CCA), carotid bifurcation (CB), and internal carotid artery (ICA). Results: Participants were categorized into two groups according to the presence or absence of SBIs, and we then compared the clinical characteristics of the two groups. Age, hypertension, increased HbA1c level, and decreased estimated glomerular filtration rate were found to be significantly associated with the SBI group. The odds ratio (OR) of the maximum IMT at the CB for the presence of SBI was 4.016 (95% confidence interval [CI], 1.565-10.304), even after adjusting for potential confounding factors. In contrast, the ORs of maximum IMT at the ICA and CCA as well as CAVI and ABI were not significant. Participants with IMTs ≥2 mm at the CB had a higher probability of the presence of SBI (OR, 26.451; 95% CI, 2.404-291.00). Conclusion: The maximum IMT at the CB was significantly correlated with the presence of SBI on MRI, but ABI or CAVI did not show significant correlation. Thus, compared to CAVI or ABI, carotid ultrasonography appears to be a very useful tool for noninvasively detecting SBI. In particular, IMTs ≥2 mm at the CB on carotid ultrasonography may be practical for identifying SBIs among middle-aged Japanese individuals.

scholarly journals The silent brain infarct in carotid surgery

1986 ◽  
Vol 3 (3) ◽  
pp. 442-447 ◽  
Author(s):  
Ramon Berguer ◽  
Mary Y. Sieggreen ◽  
Alfredo Lazo ◽  
George T. Hodakowski
Keyword(s):  
Carotid Surgery ◽  
Brain Infarct ◽  
Silent Brain Infarct
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