scholarly journals Prevalence and risk factors for renal artery stenosis and chronic kidney disease in Japanese patients with peripheral arterial disease

2010 ◽  
Vol 33 (9) ◽  
pp. 911-915 ◽  
Author(s):  
Michiko Endo ◽  
Hisao Kumakura ◽  
Hiroyoshi Kanai ◽  
Yoshihiro Araki ◽  
Shu Kasama ◽  
...  
2005 ◽  
Vol 67 ◽  
pp. S44-S47 ◽  
Author(s):  
Soledad Garcia de Vinuesa ◽  
Mayra Ortega ◽  
Patricia Martinez ◽  
Marian Goicoechea ◽  
Francisco Gomez Campdera ◽  
...  

2012 ◽  
Vol 110 (1) ◽  
pp. 136-141 ◽  
Author(s):  
Jing Chen ◽  
Emile R. Mohler ◽  
Dawei Xie ◽  
Michael G. Shlipak ◽  
Raymond R. Townsend ◽  
...  

2015 ◽  
Vol 4 (6) ◽  
pp. 205846011558303 ◽  
Author(s):  
Christian Kroneberger ◽  
Christian N Enzweiler ◽  
Andre Schmidt-Lucke ◽  
Ralph-Ingo Rückert ◽  
Ulf Teichgräber ◽  
...  

Background The risk for contrast-induced nephropathy (CIN) after intra-arterial application of an iodine-based contrast material is unknown for patients with chronic kidney disease (CKD) and peripheral arterial disease (PAD). Purpose To investigate the incidence of CIN in patients with CKD and PAD. Material and Methods This retrospective study was approved by the local ethics committee. One hundred and twenty patients with 128 procedures (73 with baseline eGFR in the range of 45–60 mL/min/1.73m2, 55 with eGFR < 45 mL/min/1.73m2) were evaluated. All patients received intra-arterially an iodine-based low-osmolar contrast material (CM) after adequate intravenous hydration with isotonic NaCl 0.9% solution. CIN was defined as an increase in serum creatinine of more than 44 μmol/L within 4 days. The influence of patient-related risk factors (age, weight, body mass index, eGFR, serum creatinine, hypertension, diabetes mellitus, coronary heart disease, heart failure) and therapy-related risk factors (amount of CM, nephrotoxic drugs, number of CM applications) on CIN were examined. Results CIN developed in 0% (0/73) of procedures in patients with PAD and an eGFR in the range of 45–60 mL/min/1.73m2 and in 10.9% (6/55) of procedures in patients with an eGFR <45 mL/min/1.73m2. No risk factor significantly influenced the development of CIN, although baseline serum creatinine ( P = 0.06) and baseline eGFR ( P = 0.10) showed a considerable dependency. Conclusion Patients with an eGFR in the range of 45–60 mL/min/1.73m2 and PAD seem not at risk for CIN after intra-arterial CM application and adequate hydration. Whereas, an eGFR < 45 mL/min/1.73m2 correlated with a risk of 10.9% for a CIN.


Angiology ◽  
2017 ◽  
Vol 68 (9) ◽  
pp. 776-781 ◽  
Author(s):  
Xi-Bei Jia ◽  
Xi-Hua Hou ◽  
Qiu-Bo Ma ◽  
Xiao-Wen Cai ◽  
Yi-Ran Li ◽  
...  

Chronic kidney disease (CKD) and peripheral arterial disease (PAD) share common risk factors. We assessed renal function and the prevalence of CKD in patients with PAD and investigated the characteristics of the risk factors for CKD in this population. Renal function of 421 patients with PAD was evaluated. Among the participants, 194 (46.1%) patients had decreased estimated glomerular filtration rate (eGFR). The prevalence of CKD was much higher among patients with PAD. Hypertension (odds ratios [ORs] 2.156, 95% confidence interval [CI] 1.413-3.289, P < .001), serum uric acid (OR 3.794, 95% CI 2.220-6.450, P < .001), and dyslipidemia (OR 1.755, 95% CI 1.123-2.745, P = .014) were significantly associated with CKD and the independent risk factors for CKD in patients with PAD. CKD is common and has a high prevalence in a population with PAD. Patients with PAD may be considered as a high-risk population for CKD. Recognition and modification of risk factors for CKD might beneficially decrease CKD incidence and improve prognosis in patients with PAD.


Author(s):  
Alexander Jayadi Utama ◽  
Hippocrates Kam ◽  
Aria Kekalih

Introduction: The most common cause of the peripheral arterial disease (PAD) is atherosclerosis. PAD is associated with other atherosclerotic diseases such as renal artery stenosis (RAS). Life expectancy decreases in patients with RAS, especially those whose stenosis is above 60% but has not reached the stage of chronic kidney failure. This study aims to determine the prevalence of RAS in PAD patients, the relationship between angiographic scoring system (ANGIO Score), history of hypertension, and diabetes mellitus with the degree of RAS. Method: This research was a cross-sectional study conducted at Cipto Mangunkusumo Hospital from February to May 2019. Patients with a diagnosis of lower extremity PAD and had been assessed with CT angiography examination, were included in this study. The degree of RAS and ANGIO Score were calculated. Sampling was done by the total sampling method. Results Most patients were women 33 (50.8%), while men were 32 (49.2%). 90.8% of the patients had diabetes, while 61.5% of the sample had hypertension. Grade 1 RAS was the most found. There was no correlation between ANGIO Score on age, sex, and diabetes mellitus, but there was a significant relationship with hypertension. There was a relationship between RAS with age and hypertension, but there was no relationship with diabetes mellitus and gender. ANGIO Score and RAS had a significant relationship (p <0.001). Conclusion: There was a relationship between the ANGIO Score and the severity of RAS. The cut-off score of 9 for the ANGIO Score had a sensitivity of 85.7% and a specificity of 61.4% for predicting RAS. Keywords: peripheral arterial disease, angiographic scoring system, renal artery stenosis, CT angiography


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