scholarly journals IL12B polymorphisms are linked but not associated with Plasmodium falciparum parasitemia: a familial study in Burkina Faso

2008 ◽  
Vol 9 (5) ◽  
pp. 405-411 ◽  
Author(s):  
M Barbier ◽  
A Atkinson ◽  
F Fumoux ◽  
P Rihet
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Familial Study

scholarly journals Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso

2012 ◽  
Vol 11 (1) ◽  
pp. 108 ◽  
Author(s):  
Alexandre Atkinson ◽  
Severine Garnier ◽  
Sarwat Afridi ◽  
Francis Fumoux ◽  
Pascal Rihet
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Heparan Sulphate ◽  
Genetic Variations ◽  
Familial Study

scholarly journals Risk of Plasmodium falciparum infection in south-west Burkina Faso - potential impact of expanding eligibility for seasonal malaria chemoprevention

2021 ◽  
Author(s):  
Anne L Wilson ◽  
Steve W Lindsay ◽  
Alfred Tiono ◽  
Jean Baptiste Yaro ◽  
Hilary Ranson ◽  
...  
Keyword(s):  
Risk Factors ◽  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Malaria Transmission ◽  
Malaria Control ◽  
Control Measures ◽  
Sub Saharan Africa ◽  
South West ◽  
Seasonal Malaria Chemoprevention ◽  
The Impact

Abstract Background Burkina Faso has one of the highest malaria burdens in sub-Saharan Africa despite the mass deployment of insecticide-treated nets (ITNs) and use of seasonal malaria chemoprevention (SMC) in children aged up to 5 years. Identification of risk factors for Plasmodium falciparum infection in rural Burkina Faso could help to identify and target malaria control measures. Methods A cross-sectional survey of 1,199 children and adults was conducted during the peak malaria transmission season in south-west Burkina Faso in 2017. Logistic regression was used to identify risk factors for microscopically confirmed P. falciparum infection. A malaria transmission dynamic model was used to determine the impact on malaria cases averted of administering SMC to children aged 5–15 year old. Results P. falciparum prevalence was 32.8% in the study population. Children aged 5 to < 10 years old were at 3.74 times the odds (95% CI = 2.68–5.22, p < 0.001) and children aged 10 to 15 years old at 3.14 times the odds (95% CI = 1.20–8.21, p = 0.02) of P. falciparum infection compared to children aged less than 5 years old. Administration of SMC to children aged up to 10 years is predicted to avert an additional 57 malaria cases per 1000 population per year (9.4% reduction) and administration to children aged up to 15 years would avert an additional 89 malaria cases per 1000 population per year (14.6% reduction) in the Cascades Region, assuming coverage of pyrethroid-piperonyl butoxide ITNs. Conclusion Malaria infections were high in all age strata, although highest in children aged 5 to 15 years, despite roll out of core malaria control interventions. Given the burden of infection in school-age children, extension of the eligibility criteria for SMC could help reduce the burden of malaria in Burkina Faso and other countries in the region.

In vivo sensitivity of Plasmodium falciparum to chloroquine in Burkina Faso

1990 ◽  
Vol 84 (5) ◽  
pp. 670-671
Author(s):  
G. Rotigliano ◽  
L. Lamizana ◽  
P.G. Procacci ◽  
S. Kumlien
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso

Is Fc gamma receptor IIA (FcγRIIA) polymorphism associated with clinical malaria and Plasmodium falciparum specific antibody levels in children from Burkina Faso?

Acta Tropica ◽  
2015 ◽  
Vol 142 ◽  
pp. 41-46 ◽  
Author(s):  
Mariama K. Cherif ◽  
Guillaume S. Sanou ◽  
Edith C. Bougouma ◽  
Amidou Diarra ◽  
Alphonse Ouédraogo ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Specific Antibody ◽  
Clinical Malaria ◽  
Fc Gamma Receptor ◽  
Gamma Receptor ◽  
Antibody Levels

scholarly journals Plasmodium falciparum genotypes diversity in symptomatic malaria of children living in an urban and a rural setting in Burkina Faso

2009 ◽  
Vol 8 (1) ◽  
pp. 135 ◽  
Author(s):  
Issiaka Soulama ◽  
Issa Nébié ◽  
Alphonse Ouédraogo ◽  
Adama Gansane ◽  
Amidou Diarra ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Rural Setting ◽  
Symptomatic Malaria

scholarly journals Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso

2012 ◽  
Vol 11 (1) ◽  
pp. 308 ◽  
Author(s):  
Sarwat Afridi ◽  
Alexandre Atkinson ◽  
Séverine Garnier ◽  
Francis Fumoux ◽  
Pascal Rihet
Keyword(s):  
Plasmodium Falciparum ◽  
Burkina Faso ◽  
Resistance Genes ◽  
Igg Subclasses ◽  
Blood Stage

scholarly journals Persistent sub-microscopic Plasmodium falciparum parasitaemia 72 hours after treatment with artemether-lumefantrine predicts 42-day treatment failure in Mali and Burkina Faso

2021 ◽  
Author(s):  
Khalid B Beshir ◽  
Nouhoum Diallo ◽  
Fabrice A Somé ◽  
Salif Sombie ◽  
Issaka Zongo ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
West Africa ◽  
Burkina Faso ◽  
Large Scale ◽  
Day Treatment ◽  
Controlled Trial ◽  
Parasite Clearance ◽  
Time Interval ◽  
Clinical Episode ◽  
Randomised Controlled

A recent randomised controlled trial, WANECAM, conducted at seven centres in West Africa, found that artemether-lumefantrine, artesunate-amodiaquine, pyronaridine-artesunate and dihydroartemisinin-piperaquine all displayed good efficacy. However, artemether-lumefantrine was associated with a shorter interval between clinical episodes than the other regimens. In a further comparison of these therapies, we identified cases of persisting sub-microscopic parasitaemia by qPCR at 72h post-treatment among WANECAM participants from 5 sites in Mali and Burkina Faso, and compared treatment outcomes for this group to those with complete parasite clearance by 72h. Among 547 evaluable patients, 17.7% had qPCR-detectable parasitaemia at 72h during their first treatment episode. This proportion varied among sites, reflecting differences in malaria transmission intensity, but did not differ among pooled drug treatment groups. However, patients who received artemether-lumefantrine and were qPCR positive at 72h were significantly more likely to have microscopically-detectable recurrent Plasmodium falciparum parasitaemia by day 42 than those receiving other regimens, and experienced on average a shorter time-interval before the next clinical episode. Haplotypes of pfcrt and pfmdr1 were also evaluated in persisting parasites. These data identify a possible threat to the parasitological efficacy of artemether-lumefantrine in West Africa, over a decade since it was first introduced on a large scale.

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