scholarly journals Effectiveness and safety of nutritional supplements in the treatment of hereditary retinal dystrophies: a systematic review

Eye ◽  
2016 ◽  
Vol 31 (2) ◽  
pp. 273-285 ◽  
Author(s):  
N Brito-García ◽  
T del Pino-Sedeño ◽  
M M Trujillo-Martín ◽  
R M Coco ◽  
E Rodríguez de la Rúa ◽  
...  
Keyword(s):  
Systematic Review ◽  
Nutritional Supplements ◽  
Retinal Dystrophies ◽  
Hereditary Retinal Dystrophies

scholarly journals Effectiveness of Oral Nutritional Supplements on Older People with Anorexia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Nutrients ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 835
Author(s):  
Mengqi Li ◽  
Si Zhao ◽  
Shuang Wu ◽  
Xiufen Yang ◽  
Hui Feng
Keyword(s):  
Systematic Review ◽  
Body Weight ◽  
Older People ◽  
Energy Intake ◽  
Meta Analysis ◽  
Nutritional Supplements ◽  
The Elderly ◽  
Randomized Controlled ◽  
Oral Nutritional Supplements ◽  
Positive Effect

Background: Nutrition plays an important role in maintaining the overall health of older people. Inadequate intake may lead to impaired body function, higher morbidity, and mortality. Oral nutritional supplements (ONS) showed positive effect on the nutritional status of the elderly; however, systematic evidence is currently lacking on the effect of ONS on the elderly with anorexia. Aims: The current systematic review and meta-analysis included randomized controlled trial (RCT) articles to investigate the effectiveness of ONS on the main aspects of anorexia of aging (AA). Methods: By using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method, researchers independently searched PubMed/MEDLINE, EMBASE, CINAHL, PsycINFO, the Cochrane Library, China National Knowledge Infrastructure (CNKI) and other gray literature resources for publications that met the inclusion criteria by October 2020. The Cochrane Risk of Bias Tools were used for quality assessment. The inverse-variance method was used for the fixed model (FM) while the DerSimonian–Laird method was used for the random model (RM). Respective 95% confidence intervals (95% CIs), mean difference (MD) or standardized mean difference (SMD) was used for indices in terms of effect size (ES). Results: 2497 records were found through the systematic search, while 17 RCTs (n = 1204) were included, with a mean age of 81.9 years (range: 74–87 years). Supplementation occurred in the morning, mid-day, and evening, while the times varied from one to three times a day. The results of meta-analysis showed that, generally, ONS had a positive effect on the overall appetite, MD = 0.18, 95% CI (0.03, 0.33), p = 0.02, and consumption, MD = 1.43, 95% CI (0.01, 2.86), p = 0.05; but not significant in terms of other aspects of appetite: hunger, p = 0.73; fullness, p = 0.60; desire to eat, p = 0.80; preoccupation, p = 0.15. Additionally, it showed an increase in the overall energy intake, SMD = 0.46, 95% CI (0.29, 0.63), p < 0.001, in protein intake, SMD = 0.59, 95% CI (0.16, 1.02), p = 0.007, and in fat intake, MD = 3.47, 95% CI (1.98, 4.97), p < 0.001, while no positive effect was found on carbohydrates intake, p = 0.06. Significance differences were also found in the body weight, SMD = 0.53, 95% CI (0.41, 0.65), p < 0.001, and body mass index (BMI), MD = 0.53, 95% CI (0.12, 0.95), p = 0.01. Moreover, subgroup analyses were conducted according to the nutrient density with no positive results showed except for the low-density ONS on overall energy intake. Conclusions: The results of the present study indicated that ONS had beneficial effects on overall appetite, energy intake, body weight and BMI.

scholarly journals Nutritional supplements for neuropsychiatric symptoms in people with dementia: A systematic review and meta‐analysis

2020 ◽  
Vol 35 (11) ◽  
pp. 1285-1291 ◽  
Author(s):  
Sandra Haider ◽  
Angela Schwarzinger ◽  
Sinisa Stefanac ◽  
Pinar Soysal ◽  
Lee Smith ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Neuropsychiatric Symptoms ◽  
Nutritional Supplements ◽  
People With Dementia

A systematic review of compliance to oral nutritional supplements

2012 ◽  
Vol 31 (3) ◽  
pp. 293-312 ◽  
Author(s):  
Gary P. Hubbard ◽  
Marinos Elia ◽  
Anne Holdoway ◽  
Rebecca J. Stratton
Keyword(s):  
Systematic Review ◽  
Nutritional Supplements ◽  
Oral Nutritional Supplements

Weight Loss and Dietary Interventions for Hidradenitis Suppurativa: A Systematic Review

2019 ◽  
Vol 24 (1) ◽  
pp. 64-72 ◽  
Author(s):  
Arunima Sivanand ◽  
Wayne P. Gulliver ◽  
Chitmandeep K. Josan ◽  
Raed Alhusayen ◽  
Patrick J. Fleming
Keyword(s):  
Systematic Review ◽  
Weight Loss ◽  
Hidradenitis Suppurativa ◽  
Nutritional Supplements ◽  
Management Plan ◽  
Primary Objective ◽  
Inflammatory Disorder ◽  
Dietary Interventions ◽  
Zinc Gluconate ◽  
Excess Skin

Hidradenitis suppurativa (HS) is a common inflammatory disorder characterized by recurrent, painful, and malodorous abscesses and nodules predominantly in skin folds. HS is associated with substantial morbidity and poor quality of life. There are no curative therapies, and the only approved biologic drug has variable efficacy and requires high doses, making adjunct treatments crucial. An important risk factor for disease severity is obesity. Our primary objective was to conduct a systematic review examining weight loss and dietary interventions, in HS. Our secondary objective was to examine nutritional supplements in HS.A systematic literature search was conducted using Medline, EMBASE, and the Cochrane Database. We included all study types in adults (>18 years), with a minimum sample size of 5, examining the effects of any dietary or weight loss intervention on HS severity. Two authors screened n = 1279 articles of which 9 met inclusion criteria. All included studies were observational and all interventions were associated with various measures of decreased HS severity. Patient-controlled weight loss and bariatric surgery were associated with HS regression, though a subset of patients with significant increase in panniculi experienced exacerbations and required excision of excess skin. Diets demonstrating benefit eliminated dairy and brewer’s yeast. Nutritional supplements including zinc gluconate, vitamin D, and riboflavin had a suppressive, rather than curative, effect on HS lesions in single studies. Overall, the reviewed interventions show promise as potential adjunct treatments in a HS management plan. Prospective randomized controlled trials should validate these findings.

scholarly journals Oral nutritional supplements for preventing surgical site infections: protocol for a systematic review and meta-analysis

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Nicholas Ralph ◽  
Lindsay Brown ◽  
Kristy L. McKillop ◽  
Jed Duff ◽  
Sonya Osborne ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Surgical Site Infections ◽  
Nutritional Supplements ◽  
Oral Nutritional Supplements
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