scholarly journals The diagnostic accuracy of spectral-domain optical coherence tomography for neovascular age-related macular degeneration: a comparison with fundus fluorescein angiography

Eye ◽  
2015 ◽  
Vol 29 (5) ◽  
pp. 602-610 ◽  
Author(s):  
C Wilde ◽  
M Patel ◽  
A Lakshmanan ◽  
R Amankwah ◽  
S Dhar-Munshi ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Diagnostic Accuracy ◽  
Macular Degeneration ◽  
Fluorescein Angiography ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Fundus Fluorescein Angiography ◽  
Age Related

scholarly journals Grading of Age-Related Macular Degeneration: Comparison between Color Fundus Photography, Fluorescein Angiography, and Spectral Domain Optical Coherence Tomography

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Nils F. Mokwa ◽  
Tina Ristau ◽  
Pearse A. Keane ◽  
Bernd Kirchhof ◽  
Srinivas R. Sadda ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Fluorescein Angiography ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Fundus Photography ◽  
Optical Coherence ◽  
Age Related ◽  
Sensitivity Specificity ◽  
And Control

Purpose. To compare color fundus photography (FP), fluorescein angiography (FA), and spectral domain optical coherence tomography (SDOCT) for the detection of age-related macular degeneration (AMD), choroidal neovascularisation (CNV), and CNV activity.Methods. FPs, FAs, and SDOCT volume scans from 120 eyes of 66 AMD and control patients were randomly collected. Control eyes were required to show no AMD, but other retinal pathology was allowed. The presence of drusen, pigmentary changes, CNV, and signs for CNV activity was independently analyzed for all imaging modalities.Results. AMD was diagnosed based on FP in 75 eyes. SDOCT and FA showed sensitivity (specificity) of 89% (76%) and 92% (82%), respectively. CNV was present on FA in 68 eyes. Sensitivity (specificity) was 78% (100%) for FP and 94% (98%) for SDOCT. CNV activity was detected by SDOCT or FA in 60 eyes with an agreement in 46 eyes. Sensitivity was 88% for SDOCT and 88% for FA. FP showed sensitivity of 38% and specificity of 98%.Conclusions. CNV lesions and activity may be missed by FP alone, but FP may help identifying drusen and pigmentary changes. SDOCT is highly sensitive for the detection of AMD, CNV, and CNV activity; however, it cannot fully replace FA.

scholarly journals Assessing Dry Age-Related Macular Degeneration in a Mexican Population with Fundus Autofluorescence and Spectral Domain Optical Coherence Tomography

2018 ◽  
Vol 09 (05) ◽  
Author(s):  
Renata del Carmen Garcia Franco ◽  
Marlon Rafael Garcia Roa ◽  
Veronica Romero Morales ◽  
Miguel Angel Vazquez Membrillo ◽  
Ximena Mira Lorenzo ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Mexican Population ◽  
Age Related Macular Degeneration ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Age Related
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