scholarly journals Reliability and validity of Cirrus and Spectralis optical coherence tomography for detecting retinal atrophy in Alzheimer’s disease

Eye ◽  
2014 ◽  
Vol 28 (6) ◽  
pp. 680-690 ◽  
Author(s):  
V Polo ◽  
E Garcia-Martin ◽  
M P Bambo ◽  
J Pinilla ◽  
J M Larrosa ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optical Coherence Tomography ◽  
Reliability And Validity ◽  
Optical Coherence ◽  
Retinal Atrophy

Retinal alterations in mild cognitive impairment and Alzheimer’s disease: an optical coherence tomography study

2014 ◽  
Vol 261 (8) ◽  
pp. 1522-1530 ◽  
Author(s):  
Francisco J. Ascaso ◽  
Nancy Cruz ◽  
Pedro J. Modrego ◽  
Raul Lopez-Anton ◽  
Javier Santabárbara ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optical Coherence Tomography ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Optical Coherence

scholarly journals Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

2019 ◽  
Vol 8 (7) ◽  
pp. 996 ◽  
Author(s):  
Delia Cabrera DeBuc ◽  
Magdalena Gaca-Wysocka ◽  
Andrzej Grzybowski ◽  
Piotr Kanclerz
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Optical Coherence Tomography ◽  
Retinal Blood Flow ◽  
Optical Coherence ◽  
Ocular Diseases ◽  
Challenges And Opportunities ◽  
Retinal Structure ◽  
And Function ◽  
The Impact

This review will highlight recent insights into measuring retinal structure in Alzheimer’s disease (AD). A growing body of evidence indicates that disturbances in retinal blood flow and structure are related to cognitive function, which can severely impair vision. Optical coherence tomography (OCT) is an optical imaging technology that may allow researchers and physicians to gain deeper insights into retinal morphology and clarify the impact of AD on retinal health and function. Direct and noninvasive measurement of retinal morphology using OCT has provided useful diagnostic and therapeutic indications in several central nervous system (CNS) diseases, including AD, multiple sclerosis, and Parkinson disease. Despite several limitations, morphology assessment in the retinal layers is a significant advancement in the understanding of ocular diseases. Nevertheless, additional studies are required to validate the use of OCT in AD and its complications in the eye.

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