scholarly journals A case of intermediate uveitis as a precursor to acute disseminated encephalomyelitis (ADEM) in a teenager

Eye ◽  
2014 ◽  
Vol 28 (5) ◽  
pp. 625-627
Author(s):  
P Y Tan ◽  
J Furness ◽  
A S Sohal ◽  
V Ramesh ◽  
S Haider
Keyword(s):  
Acute Disseminated Encephalomyelitis ◽  
Intermediate Uveitis

Clinical long term follow-up of children presenting with a severe acute disseminated encephalomyelitis (ADEM)

2008 ◽  
Vol 39 (05) ◽  
Author(s):  
A Nagl ◽  
S Lütjen ◽  
S Zotter ◽  
A Blaschek ◽  
C Korenke ◽  
...  
Keyword(s):  
Acute Disseminated Encephalomyelitis ◽  
Long Term Follow Up

Anti-Myelin Oligodendrocyte Glycoprotein Encephalomyelitis and Extensive Longitudinal Transverse Myelitis Associated with Compound Heterozygous NLRP3 Missense Mutations in a Young Child

2020 ◽  
Author(s):  
Deirdre O'Sullivan ◽  
Michael Moore ◽  
Susan Byrne ◽  
Andreas O. Reiff ◽  
Susanna Felsenstein
Keyword(s):  
Young Child ◽  
Genetic Basis ◽  
Transverse Myelitis ◽  
Acute Disseminated Encephalomyelitis ◽  
Myelin Oligodendrocyte Glycoprotein ◽  
Compound Heterozygous ◽  
Missense Mutations ◽  
Childhood Onset

AbstractAcute disseminated encephalomyelitis in association with extensive longitudinal transverse myelitis is reported in a young child with positive anti-myelin oligodendrocyte glycoprotein (MOG) antibody with heterozygous NLRP3 missense mutations; p.(Arg488Lys) and p.(Ser159Ile). This case may well present an exceptional coincidence, but may describe a yet unrecognized feature of the spectrum of childhood onset cryopyrinopathies that contribute to the understanding of the genetic basis for anti-MOG antibody positive encephalomyelitis. Based on this observation, a larger scale study investigating the role of NLRP3 and other inflammasomes in this entity would provide important pathophysiological insights and potentially novel avenues for treatment.

ACUTE DISSEMINATED ENCEPHALOMYELITIS (ADEM)

2006 ◽  
Vol 37 (S 1) ◽  
Author(s):  
A Alrumayan ◽  
M Aldubayee
Keyword(s):  
Acute Disseminated Encephalomyelitis
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