scholarly journals Neovascular age-related macular degeneration: decision making and optimal management

Eye ◽  
2010 ◽  
Vol 24 (3) ◽  
pp. 497-505 ◽  
Author(s):  
S P Harding
Keyword(s):  
Decision Making ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optimal Management ◽  
Age Related

Distinguishing Central Serous Chorioretinopathy From Neovascular Age-Related Macular Degeneration: A Prospective Study

2020 ◽  
Vol 4 (4) ◽  
pp. 293-299
Author(s):  
Parampal S. Grewal ◽  
Steven R.J. Lapere ◽  
Christopher J. Rudnisky ◽  
Rizwan Somani ◽  
Matthew T.S. Tennant
Keyword(s):  
Decision Making ◽  
Macular Degeneration ◽  
Central Serous Chorioretinopathy ◽  
Choroidal Thickness ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Pigment Epithelial ◽  
Age Related

Purpose: This article identifies clinical features that differentiate central serous chorioretinopathy (CSR) from neovascular age-related macular degeneration (nAMD) and uses this information to develop a diagnostic tool. Methods: A prospective observational study was conducted of patients with a new diagnosis of CSR, nAMD, or indeterminate presentation. All patients underwent clinical assessment, axial length measurement, enhanced-depth imaging–optical coherence tomography, and intravenous fluorescein angiography. A final consensus diagnosis was derived following review of these factors. Results: A total of 56 eyes of 56 patients were enrolled (CSR = 34; nAMD = 22). The subfoveal choroidal thickness was greater in the CSR group (421 ± 106 µm) than the nAMD group (219 ± 91 µm, P < .001). The following odds ratio of CSR reached statistical significance: age 70 and younger (72.00, 95% CI: 11.99-432.50), subfoveal choroidal thickness greater than or equal to 300 µm (33.92, 95% CI: 4.06-283.18), dome-shaped neurosensory detachment (13.24, 95% CI: 3.22-54.45), retinal pigment epithelial changes (0.31, 95% CI: 0.10-0.97), subretinal hyperreflective material (0.11, 95% CI: 0.03-0.42), and fibrovascular pigment epithelial detachment (0.05, 95% CI: 0.01-0.47). A stepwise CSR vs nAMD clinical decision-making algorithm is proposed. Conclusions: Choroidal thickness is increased in CSR when compared with nAMD. The presented odds ratios and the CSR vs nAMD clinical decision-making tool can be applied to distinguish CSR from nAMD.

scholarly journals Mixed (combined) phenotype of the late stage of age-related macular degeneration

2021 ◽  
Vol 14 (2) ◽  
pp. 69-75
Author(s):  
N. V. Neroeva ◽  
V. V. Neroev ◽  
M. V. Ryabina ◽  
A. G. Karmokova ◽  
O. A. Losanova
Keyword(s):  
Macular Degeneration ◽  
Late Stage ◽  
Geographic Atrophy ◽  
Accurate Diagnosis ◽  
The Other ◽  
Age Related Macular Degeneration ◽  
Complex Structures ◽  
Optimal Management ◽  
Age Related ◽  
Mixed Phenotype

With multimodal visualization of the chorioretinal complex structures using modern research methods, it was possible to isolatea mixed, or combined, phenotype of the late stage of age-related macular degeneration (AMD). Early detection of this AMD form is of vital importance not only for accurate diagnosis, but for choosing optimal management tactics for patients. The paper presents two clinical cases with different variants of the development of the mixed phenotype of the late AMD stage. In one case, the long-lasting “geographic atrophy” (GA) was complicated by the development of choroidal neovascularization, while in the other case GA appeared during the treatment of wetAMD.

scholarly journals Patient experience of treatment decision making for wet age-related macular degeneration disease: a qualitative study in China

BMJ Open ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. e031020
Author(s):  
Wei Bian ◽  
Junli Wan ◽  
Mingqiong Tan ◽  
Xiaoqing Wu ◽  
Jun Su ◽  
...  
Keyword(s):  
Decision Making ◽  
Data Analysis ◽  
Qualitative Study ◽  
Macular Degeneration ◽  
Patient Experience ◽  
Financial Burden ◽  
Treatment Decision ◽  
Age Related Macular Degeneration ◽  
Treatment Decision Making ◽  
Age Related

ObjectivesThis study aimed to investigate the experience of patients with wet age-related macular degeneration (wAMD) in treatment decision-making process.DesignA descriptive qualitative study was designed by using semistructured interviews, and the data analysis was conducted with the thematic analysis approach.Participants and settingA convenient and purposive sample of 21 participants diagnosed with wAMD was recruited from May 2018 to September 2018. The study was conducted in the Eye Clinic of Southwest Hospital of Army Medical University in Chongqing located in the southwest of China.ResultsThe mean age of the participants was 64.48 years (ranging 50–81 years), and the duration of the disease ranged from 6 months to 48 months. Four major themes were identified from the original data analysis. These themes included facing the darkness (choosing from light and darkness and living in pain), constraints on decision making (doctor-oriented decision making, inadequacy of options and time), weighing alternatives (family influence, financial burden and maintaining social function) and decision-making support (professional decision-making assistance and peer support).ConclusionThis is a qualitative study attempting to explore the patient experience of treatment decision making for wAMD disease in China. Previous literature has focused on treatment effect and symptoms, rather than the individual experience and the wide contexts from a sociocultural perspective. Further studies, such as cross-sectional studies, can be used to describe the status and determine the influencing factors of decision0making process, so as to develop an impact factor model of decision making and to formulate an intervention for patients with wAMD.

scholarly journals Artificial intelligence-based decision-making for age-related macular degeneration

Theranostics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 232-245 ◽  
Author(s):  
De-Kuang Hwang ◽  
Chih-Chien Hsu ◽  
Kao-Jung Chang ◽  
Daniel Chao ◽  
Chuan-Hu Sun ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Decision Making ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals OPTIMAL MANAGEMENT OF PIGMENT EPITHELIAL DETACHMENTS IN EYES WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION

Retina ◽  
2018 ◽  
Vol 38 (11) ◽  
pp. 2103-2117 ◽  
Author(s):  
Arshad M. Khanani ◽  
David Eichenbaum ◽  
Patricio G. Schlottmann ◽  
Lisa Tuomi ◽  
David Sarraf
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Optimal Management ◽  
Pigment Epithelial ◽  
Age Related
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