scholarly journals Second eye involvement in age-related macular degeneration: A four-year prospective study

Eye ◽  
1990 ◽  
Vol 4 (6) ◽  
pp. 813-818 ◽  
Author(s):  
Monique Roy ◽  
Muriel Kaiser-Kupfer
Keyword(s):  
Prospective Study ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Eye Involvement

A Comparison of Radial and Horizontal Macular Optical Coherence Tomography on Detection of Macular Pathology: A Prospective Study at an Academic Institution

2021 ◽  
pp. 247412642199705
Author(s):  
Halward M.J. Blegen ◽  
Samuel D. Hobbs ◽  
Reggie Taylor ◽  
Andrew L. Plaster ◽  
Paul M. Drayna
Keyword(s):  
Optical Coherence Tomography ◽  
Prospective Study ◽  
Macular Degeneration ◽  
Epiretinal Membrane ◽  
Central Serous Chorioretinopathy ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related ◽  
Macular Diseases ◽  
A Prospective Study

Purpose: Optical coherence tomography (OCT) is useful in diagnosing and monitoring retinal pathology such as age-related macular degeneration, diabetic macular edema (DME), central serous chorioretinopathy, and epiretinal membrane, among others. This study compared the ability of horizontal (H) 25-, 13-, and 7-cut macular OCT vs 24-, 12-, and 6-cut radial (R) macular OCT in identifying various macular pathology. Methods: This was a prospective study of 161 established patients evaluated at Wilford Hall Eye Center Retina Clinic between September and October of 2019. Pathology included age-related macular degeneration, central serous chorioretinopathy, DME, and epiretinal membrane, among others. Patients obtained 25-, 13-, and 7-cut H raster OCT as well as 24-, 12-, and 6-cut R OCT. Primary outcomes were sensitivity in detecting macular fluid and each macular abnormality. Results: The 24-cut radial (R24) OCT equally or out-performed the H25 (horizontal 25-cut OCT) in detecting macular fluid across all pathological groups. Generally, a higher number of cuts correlated with better detection of fluid. In detecting any macular abnormalities, H25, R24, and R12 had 100% sensitivity. R6 OCT had near 100% sensitivity across all groups, except for DME (95%). Overall, R OCT had better sensitivity (0.960) than H OCT (0.907) in detecting macular pathology. Conclusions: R outperformed H macular OCT in detecting fluid and other abnormalities. Clinically, both scanning patterns can be used by ophthalmologists in diagnosis and management of commonly encountered macular diseases. Technicians may be able to use a variety of these scans to screen for pathology prior to physician evaluation.

A Prospective Study of Alcohol Consumption and the Risk of Age-Related Macular Degeneration

1999 ◽  
Vol 9 (3) ◽  
pp. 172-177 ◽  
Author(s):  
Umed A Ajani ◽  
William G Christen ◽  
Joann E Manson ◽  
Robert J Glynn ◽  
Debra Schaumberg ◽  
...  
Keyword(s):  
Alcohol Consumption ◽  
Prospective Study ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
A Prospective Study

Intravitreal Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration: A One-year Prospective Study

2008 ◽  
Vol 145 (2) ◽  
pp. 249-256.e2 ◽  
Author(s):  
Ziad F. Bashshur ◽  
Zeina A. Haddad ◽  
Alexandre Schakal ◽  
Rola F. Jaafar ◽  
Marc Saab ◽  
...  
Keyword(s):  
Prospective Study ◽  
Macular Degeneration ◽  
Intravitreal Bevacizumab ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
One Year

scholarly journals Incidence of Fellow Eye Involvement in Patients With Unilateral Exudative Age-Related Macular Degeneration

2018 ◽  
Vol 136 (8) ◽  
pp. 905 ◽  
Author(s):  
Yasuo Yanagi ◽  
Aditi Mohla ◽  
Shu Yen Lee ◽  
Ranjana Mathur ◽  
Choi Mun Chan ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Fellow Eye ◽  
Age Related ◽  
Eye Involvement

scholarly journals Moorfields AMD database report 2: fellow eye involvement with neovascular age-related macular degeneration

2019 ◽  
Vol 104 (5) ◽  
pp. 684-690 ◽  
Author(s):  
Katrin Fasler ◽  
Dun Jack Fu ◽  
Gabriella Moraes ◽  
Siegfried Wagner ◽  
Eesha Gokhale ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Time Interval ◽  
Data Set ◽  
Fellow Eye ◽  
Age Related ◽  
Eye Involvement ◽  
Baseline Characteristics ◽  
Involvement Rate ◽  
Fellow Eyes

Background/AimsNeovascular age-related macular degeneration (nAMD) is frequently bilateral, and previous reports on ‘fellow eyes’ have assumed sequential treatment after a period of treatment of the first eye only. The aim of our study was to analyse baseline characteristics and visual acuity (VA) outcomes of fellow eye involvement with nAMD, specifically differentiating between sequential and non-sequential (due to macular scarring in the first eye) antivascular endothelial growth factor treatment and timelines for fellow eye involvement.MethodsRetrospective, electronic medical record database study of the Moorfields AMD database of 6265 patients/120 286 single entries with data extracted between 21 October 2008 and 9 August 2018. The data set for analysis consisted of 1180 sequential, 807 non-sequential and 3410 unilateral eyes.ResultsMean VA (ETDRS letters±SD) of sequentially treated fellow eyes at baseline was significantly higher (63±13), VA gain over 2 years lower (0.37±14) and proportion of eyes with good VA (≥70 letters) higher (46%) than the respective first eyes (baseline VA 54±16, VA gain at 2 years 5.6±15, percentage of eyes with good VA 39%). Non-sequential fellow eyes showed baseline characteristics and VA outcomes similar to first eyes. Fellow eye involvement rate was 32% at 2 years, and median time interval to fellow eye involvement was 71 (IQR: 27–147) weeks.ConclusionThis report shows that sequentially treated nAMD fellow eyes have better baseline and final VA than non-sequentially treated eyes after 2 years of treatment. Sequentially treated eyes also had a greater proportion with good VA after 2 years.

Epilutein for Early-Stage Age-Related Macular Degeneration: A Randomized and Prospective Study

2017 ◽  
Vol 58 (4) ◽  
pp. 231-241 ◽  
Author(s):  
Raimondo Forte ◽  
Lucia Panzella ◽  
Ida Cesarano ◽  
Gilda Cennamo ◽  
Thomas Eidenberger ◽  
...  
Keyword(s):  
Prospective Study ◽  
Macular Degeneration ◽  
Early Stage ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals The Moorfields AMD Database Report 2 - Fellow Eye Involvement with Neovascular Age-related Macular Degeneration

2019 ◽  
Author(s):  
Katrin Fasler ◽  
Gabriella Moraes ◽  
Dun Jack Fu ◽  
Siegfried K. Wagner ◽  
Eesha Gokhale ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Time Interval ◽  
Fellow Eye ◽  
Age Related ◽  
Stage Disease ◽  
Eye Involvement ◽  
Baseline Characteristics ◽  
Involvement Rate ◽  
Fellow Eyes

ABSTRACTBackground/AimsNeovascular age-related macular degeneration (nAMD) is frequently bilateral, and previous reports on ‘fellow eyes’’ have assumed sequential treatment after a period of treatment of the first eye only. The aim of our study was to analyse baseline characteristics and visual acuity (VA) outcomes of fellow eye involvement with nAMD, specifically differentiating between sequential and non-sequential (due to macular scarring in the first eye) anti-vascular endothelial growth factor treatment and timelines for fellow eye involvement.MethodsRetrospective, electronic medical record database study of the Moorfields AMD database of 8174 eyes/120,756 single entries with data extracted between October 21, 2008 and August 9, 2018. The dataset for analysis consisted of 1180 sequential, 413 nonsequential, and 1110 unilateral eyes.ResultsMean VA of sequentially treated fellow eyes at baseline was significantly higher (62±13), VA gain over two years lower (0.65±14), and proportion of eyes with good VA (≥20/40 or 70 letters) higher (46%) than the respective first eyes (baseline VA 54±16, VA gain at two years 5.6±15, percentage of eyes with good VA 38%). Non-sequential fellow eyes showed baseline characteristics and VA outcomes similar to first eyes. Fellow eye involvement rate was 32% at two years, and median time interval to fellow eye involvement was 71 (IQR 27-147) weeks.ConclusionThis reports shows sequentially treated nAMD fellow eyes have better baseline and final VA than non-sequentially treated eyes after 2 years of treatment. Sequentially treated eyes also had a greater proportion with good VA after 2 years of treatment.PRECISDepending on age, fellow eye involvement occurs in 32% of patients with neovascular AMD by two years. Fellow eyes generally maintain better vision, except in cases where late-stage disease in the first eye was untreated.

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