scholarly journals Inhibitory effects of epigallocatechin gallate on compound 48/80-inducedmast cell activation and passive cutaneous anaphylaxis

2005 ◽  
Vol 37 (4) ◽  
pp. 290-296 ◽  
Author(s):  
Guang Zhao Li ◽  
Ok Hee Chai ◽  
Chang Ho Song
Keyword(s):  
Cell Activation ◽  
Epigallocatechin Gallate ◽  
Passive Cutaneous Anaphylaxis ◽  
Inhibitory Effects

scholarly journals Inhibitory Effects of Ecklonia cava Extract on High Glucose-Induced Hepatic Stellate Cell Activation

Marine Drugs ◽  
2011 ◽  
Vol 9 (12) ◽  
pp. 2793-2808 ◽  
Author(s):  
Kumiko Yokogawa ◽  
Isao Matsui-Yuasa ◽  
Akiko Tamura ◽  
Masaki Terada ◽  
Akiko Kojima-Yuasa
Keyword(s):  
Hepatic Stellate Cell ◽  
High Glucose ◽  
Cell Activation ◽  
Stellate Cell ◽  
Ecklonia Cava ◽  
Inhibitory Effects ◽  
Hepatic Stellate Cell Activation

Fatty acid metabolism in breast cancer cells: differential inhibitory effects of epigallocatechin gallate (EGCG) and C75

2007 ◽  
Vol 109 (3) ◽  
pp. 471-479 ◽  
Author(s):  
Teresa Puig ◽  
Alejandro Vázquez-Martín ◽  
Joana Relat ◽  
Jordi Pétriz ◽  
Javier A. Menéndez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Fatty Acid ◽  
Cancer Cells ◽  
Fatty Acid Metabolism ◽  
Breast Cancer Cells ◽  
Acid Metabolism ◽  
Epigallocatechin Gallate ◽  
Inhibitory Effects

scholarly journals Inhibitory Effects of Daiokanzoto (Da-Huang-Gan-Cao-Tang) on P-Glycoprotein

2012 ◽  
Vol 2012 ◽  
pp. 1-7
Author(s):  
Yuka Watanabe ◽  
Nobutomo Ikarashi ◽  
Toshiyuki Satoh ◽  
Kiyomi Ito ◽  
Wataru Ochiai ◽  
...  
Keyword(s):  
Epigallocatechin Gallate ◽  
Licorice Root ◽  
Drug Transporter ◽  
Inhibitory Effects ◽  
Epicatechin Gallate ◽  
Glycoprotein P ◽  
Atpase Assay ◽  
P Glycoprotein ◽  
Herbal Ingredient

We have studied the effects of various Kampo medicines on P-glycoprotein (P-gp), a drug transporter,in vitro. The present study focused on Daiokanzoto (Da-Huang-Gan-Cao-Tang), which shows the most potent inhibitory effects on P-gp among the 50 Kampo medicines studied, and investigated the P-gp inhibitory effects of Daiokanzoto herbal ingredients (rhubarb and licorice root) and their components by an ATPase assay using human P-gp membrane. Both rhubarb and licorice root significantly inhibited ATPase activity, and the effects of rhubarb were more potent than those of licorice root. The content of rhubarb in Daiokanzoto is double that in licorice root, and the inhibition patterns of Daiokanzoto and rhubarb involve both competitive and noncompetitive inhibition, suggesting that the inhibitory effects of Daiokanzoto are mainly due to rhubarb. Concerning the components of rhubarb, concentration-dependent inhibitory effects were observed for (−)-catechin gallate, (−)-epicatechin gallate, and (−)-epigallocatechin gallate. In conclusion, rhubarb may cause changes in the drug dispositions of P-gp substrates through the inhibition of P-gp. It appears that attention should be given to the interactions between these drugs and Kampo medicines containing rhubarb as an herbal ingredient.

scholarly journals Inhibitory Effects of (-)-Epigallocatechin Gallate on Spontaneous Hepatoma in C3H/HeNCrj Mice and Human Hepatoma-derived PLC/PRF/5 Cells

1994 ◽  
Vol 85 (3) ◽  
pp. 221-225 ◽  
Author(s):  
Hiroshi Nishida ◽  
Masahide Omori ◽  
Yasushi Fukutomi ◽  
Mitsuo Ninomiya ◽  
Shinji Nishiwaki ◽  
...  
Keyword(s):  
Epigallocatechin Gallate ◽  
Human Hepatoma ◽  
Inhibitory Effects
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