scholarly journals Relatively high mortality risk in elderly Swedish subjects with low selenium status

2015 ◽  
Vol 70 (1) ◽  
pp. 91-96 ◽  
Author(s):  
U Alehagen ◽  
P Johansson ◽  
M Björnstedt ◽  
A Rosén ◽  
C Post ◽  
...  
Keyword(s):  
High Mortality ◽  
Mortality Risk ◽  
Selenium Status ◽  
High Mortality Risk ◽  
Low Selenium

scholarly journals POS0141 ACTIVE SCREENING FOR GOUT IDENTIFIES A LARGER CARDIOVASCULAR POPULATION AT HIGH MORTALITY RISK

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 282.2-282
Author(s):  
S. Ruiz-Simón ◽  
I. Calabuig ◽  
M. Gomez-Garberi ◽  
M. Andrés
Keyword(s):  
High Mortality ◽  
Mortality Risk ◽  
Cardiovascular Events ◽  
Cox Regression ◽  
Field Studies ◽  
High Mortality Risk ◽  
Active Screening ◽  
Tertiary Centre ◽  
All Cause Mortality

Background:We have recently revealed by active screening that about a third of gout cases in the cardiovascular population is not registered in records [1], highlighting the value of field studies.Objectives:To assess whether gout screening in patients hospitalized for cardiovascular events may also help identify patients at higher risk of mortality after discharge.Methods:A retrospective cohort field study, carried out in 266 patients admitted for cardiovascular events in the Cardiology, Neurology and Vascular Surgery units of a tertiary centre in Spain. The presence of gout was established by records review and face-to-face interview, according to the 2015 ACR/EULAR criteria. The occurrence of mortality during follow-up and its causes were obtained from electronic medical records. The association between gout and subsequent mortality was tested using Cox regression models. Whether covariates affect the gout-associated mortality was also studied.Results:Of 266 patients recruited at baseline, 17 were excluded due to loss to follow-up (>6mo), leaving a final sample of 249 patients (93.6%). Thirty-six cases (14.5% of the sample) were classified as having gout: twenty-three (63.9%) had a previously registered diagnosis, while 13 (36.1%) had not and was established by the interview.After discharge, the mean follow-up was 19.9 months (SD ±8.6), with a mortality incidence of 21.6 deaths per 100 patient-years, 34.2% by cardiovascular causes.Gout significantly increased the risk of subsequent all-cause mortality, with a hazard ratio (HR) of 2.01 (95%CI 1.13 to 3.58). When the analysis was restricted to gout patients with registered diagnosis, the association remained significant (HR 2.89; 95%CI 1.54 to 5.41).The adjusted HR for all-cause mortality associated with gout was 1.86 (95% CI 1.01-3.40). Regarding the causes of death, both cardiovascular and non-cardiovascular were numerically increased.Secondary variables rising the mortality risk in those with gout were age (HR 1.07; 1.01 to 1.13) and coexistent renal disease (HR 4.70; 1.31 to 16.84), while gender, gout characteristics and traditional risk factors showed no impact.Conclusion:Gout was confirmed an independent predictor of subsequent all-cause mortality in patients admitted for cardiovascular events. Active screening for gout allowed identifying a larger population at high mortality risk, which may help tailor optimal management to minimize the cardiovascular impact.References:[1]Calabuig I, et al. Front Med (Lausanne). 2020 Sep 29;7:560.Disclosure of Interests:Silvia Ruiz-Simón: None declared, Irene Calabuig: None declared, Miguel Gomez-Garberi: None declared, Mariano Andrés Speakers bureau: Grunenthal, Menarini, Consultant of: Grunenthal, Grant/research support from: Grunenthal

scholarly journals Treatment experience of a patient with duodenal trauma

2020 ◽  
pp. 95-96
Author(s):  
A. K. Krekoten ◽  
A. A. Krekoten ◽  
V. N. Mutyl
Keyword(s):  
Small Intestine ◽  
High Mortality ◽  
Mortality Risk ◽  
Postoperative Period ◽  
Pancreatic Ducts ◽  
High Mortality Risk ◽  
Intraoperative Diagnosis ◽  
Short Loop ◽  
The Common

A case of combined duodenal trauma in the 11-year-old patient is described. Complications of pre-operative and intraoperative diagnosis as well as complicated postoperative period are emphasized to be a cause of high mortality risk in this pathology. The disconnection of proximal and distal parts of duodenum was performed; anastomoses were placed between the common bile and pancreatic ducts and small intestine, and gastroenteroanastomosis was performed on a short loop. Follow-up traced for 10 months: recovery.

scholarly journals Wilson disease: more than meets the eye

2018 ◽  
Vol 94 (1112) ◽  
pp. 335.2-347 ◽  
Author(s):  
Claire Kelly ◽  
Marinos Pericleous
Keyword(s):  
Liver Transplantation ◽  
Liver Disease ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
High Mortality ◽  
Mortality Risk ◽  
Wilson Disease ◽  
Copper Metabolism ◽  
High Mortality Risk ◽  
High Index Of Suspicion

Wilson disease is a rare but important disorder of copper metabolism, with a failure to excrete copper appropriately into bile. It is a multisystem condition with presentations across all branches of medicine. Diagnosis can be difficult and requires a high index of suspicion. It should be considered in unexplained liver disease particularly where neuropsychiatric features are also present. Treatments are available for all stages of disease. A particularly important presentation not to overlook is acute liver failure which carries a high mortality risk and may require urgent liver transplantation. Here, we provide an overview of this complex condition.

scholarly journals Positive follow-up blood cultures identify high mortality risk among patients with Gram-negative bacteraemia

2020 ◽  
Vol 26 (7) ◽  
pp. 904-910 ◽  
Author(s):  
S.A. Maskarinec ◽  
L.P. Park ◽  
F. Ruffin ◽  
N.A. Turner ◽  
N. Patel ◽  
...  
Keyword(s):  
High Mortality ◽  
Mortality Risk ◽  
Blood Cultures ◽  
High Mortality Risk ◽  
Gram Negative

scholarly journals Identification of Patients With High Mortality Risk and Prediction of Outcomes in Delirium by Bispectral EEG

2019 ◽  
Vol 80 (5) ◽  
Author(s):  
Gen Shinozaki ◽  
Nicholas L. Bormann ◽  
Aubrey C. Chan ◽  
Kasra Zarei ◽  
Nicholas A. Sparr ◽  
...  
Keyword(s):  
High Mortality ◽  
Mortality Risk ◽  
High Mortality Risk
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