scholarly journals Vitamin D deficiency in Spain: a population-based cohort study

2010 ◽  
Vol 65 (3) ◽  
pp. 321-328 ◽  
Author(s):  
I González-Molero ◽  
S Morcillo ◽  
S Valdés ◽  
V Pérez-Valero ◽  
P Botas ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Deficiency ◽  
Population Based

scholarly journals Late Pregnancy Vitamin D Deficiency is Associated with Doubled Odds of Birth Asphyxia and Emergency Caesarean Section: A Prospective Cohort Study

2020 ◽  
Vol 24 (11) ◽  
pp. 1412-1418
Author(s):  
Hanna Augustin ◽  
Sinead Mulcahy ◽  
Inez Schoenmakers ◽  
Maria Bullarbo ◽  
Anna Glantz ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Caesarean Section ◽  
Vitamin D Deficiency ◽  
Epidural Anaesthesia ◽  
Birth Asphyxia ◽  
Late Pregnancy ◽  
Population Based ◽  
Emergency Caesarean Section ◽  
Vitamin D Status

Abstract Objectives The aim of this prospective cohort study was to investigate the associations between maternal vitamin D status in late pregnancy and emergency caesarean section (EMCS) and birth asphyxia, in a population based sample of women in Sweden. Methods Pregnant women were recruited at the antenatal care in Sweden and 1832 women were included after exclusion of miscarriages, terminated pregnancies and missing data on vitamin D status. Mode of delivery was retrieved from medical records. EMCS was defined as caesarean section after onset of labour. Birth asphyxia was defined as either 5 min Apgar score < 7 or arterial umbilical cord pH < 7.1. Serum was sampled in the third trimester of pregnancy (T3) and 25-hydroxyvitamin D (25OHD) was analysed by liquid chromatography tandem mass spectrometry. Vitamin D deficiency was defined as 25OHD < 30 nmol/L, and associations were studied using logistic regression analysis and expressed as adjusted odds ratios (AOR). Results In total, 141 (7.7%) women had an EMCS and 58 (3.2%) children were born with birth asphyxia. Vitamin D deficiency was only associated with higher odds of EMCS in women without epidural anaesthesia (AOR = 2.01, p = 0.044). Vitamin D deficiency was also associated with higher odds of birth asphyxia (AOR = 2.22, p = 0.044). Conclusions for Practice In this Swedish prospective population-based cohort study, vitamin D deficiency in late pregnancy was associated with doubled odds of birth asphyxia and with EMCS in deliveries not aided by epidural anaesthesia. Prevention of vitamin D deficiency among pregnant women may reduce the incidence of EMCS and birth asphyxia. The mechanism behind the findings require further investigation.

scholarly journals Vitamin D deficiency is associated with hepatic decompensation and inflammation in patients with liver cirrhosis: A prospective cohort study

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0207162 ◽  
Author(s):  
Alica Kubesch ◽  
Leonie Quenstedt ◽  
Maged Saleh ◽  
Sabrina Rüschenbaum ◽  
Katharina Schwarzkopf ◽  
...  
Keyword(s):  
Vitamin D ◽  
Liver Cirrhosis ◽  
Cohort Study ◽  
Vitamin D Deficiency ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Hepatic Decompensation

Association of maternal vitamin D deficiency and infants' neurodevelopmental status: A cohort study on vitamin D and its impact during pregnancy and childhood in Indonesia

2019 ◽  
Vol 56 (1) ◽  
pp. 16-21 ◽  
Author(s):  
Meita Dhamayanti ◽  
Anindita Noviandhari ◽  
Stephani Supriadi ◽  
Raden TD Judistiani ◽  
Budi Setiabudiawan
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Deficiency ◽  
Maternal Vitamin

Vitamin D deficiency and infection risk in kidney transplant recipients: A single-center cohort study

2018 ◽  
Vol 20 (6) ◽  
pp. e12988 ◽  
Author(s):  
Mario Fernández-Ruiz ◽  
Laura Corbella ◽  
Alejandra Morales-Cartagena ◽  
Esther González ◽  
Natalia Polanco ◽  
...  
Keyword(s):  
Vitamin D ◽  
Cohort Study ◽  
Vitamin D Deficiency ◽  
Kidney Transplant ◽  
Infection Risk ◽  
Transplant Recipients ◽  
Single Center ◽  
Kidney Transplant Recipients

scholarly journals Vitamin D prescribing in children in UK primary care practices: a population-based cohort study

BMJ Open ◽  
2019 ◽  
Vol 9 (12) ◽  
pp. e031870 ◽  
Author(s):  
Mandy Wan ◽  
Laura J Horsfall ◽  
Emre Basatemur ◽  
Jignesh Prakash Patel ◽  
Rukshana Shroff ◽  
...  
Keyword(s):  
Primary Care ◽  
Vitamin D ◽  
Cohort Study ◽  
Clinical Symptoms ◽  
Population Based ◽  
Vitamin D Supplementation ◽  
Annual Incidence ◽  
Health Improvement ◽  
Laboratory Test Results ◽  
General Practices

ObjectiveTo examine temporal changes in the incidence and patterns of vitamin D supplementation prescribing by general practitioners (GPs) between 2008 and 2016.DesignPopulation-based cohort study.SettingUK general practice health records from The Health Improvement Network.ParticipantsChildren aged 0 to 17 years who were registered with their general practices for at least 3 months.Outcome measuresAnnual incidence rates of vitamin D prescriptions were calculated, and rate ratios were estimated using multivariable Poisson regression to explore differences by sociodemographic factors. Data on the type of supplementation, dose, dosing schedule, linked 25-hydroxyvitamin D (25(OH)D) laboratory test results and clinical symptoms suggestive of vitamin D deficiency were analysed.ResultsAmong 2 million children, the crude annual incidence of vitamin D prescribing increased by 26-fold between 2008 and 2016 rising from 10.8 (95% CI: 8.9 to 13.1) to 276.8 (95% CI: 264.3 to 289.9) per 100 000 person-years. Older children, non-white ethnicity and general practices in England (compared with Wales/Scotland/Northern Ireland) were independently associated with higher rates of prescribing. Analyses of incident prescriptions showed inconsistent supplementation regimens with an absence of pre-supplementation 25(OH)D concentrations in 28.7% to 56.4% of prescriptions annually. There was an increasing trend in prescribing at pharmacological doses irrespective of 25(OH)D concentrations, deviating in part from UK recommendations. Prescribing at pharmacological doses for children with deficient status increased from 3.8% to 79.4%, but the rise was also observed in children for whom guidelines recommended prevention doses (0% to 53%). Vitamin D supplementation at pharmacological doses was also prescribed in at least 40% of children with no pre-supplementation 25(OH)D concentrations annually.ConclusionsThere has been a marked and sustained increase in vitamin D supplementation prescribing in children in UK primary care. Our data suggests that national guidelines on vitamin D supplementation for children are not consistently followed by GPs.

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