scholarly journals Antisense EGFR sequence reverses the growth properties of human liver carcinoma cell line BEL-7404 in vitro

Cell Research ◽  
1993 ◽  
Vol 3 (1) ◽  
pp. 75-83 ◽  
Author(s):  
Yonghua Xu ◽  
Wanli Jiang ◽  
Sufeng Peng ◽  
Yinghua Chen
Keyword(s):  
Cell Line ◽  
Human Liver ◽  
Carcinoma Cell ◽  
Carcinoma Cell Line ◽  
Liver Carcinoma ◽  
Growth Properties

Proteome analysis of a human liver carcinoma cell line stably expressing hepatitis delta virus ribonucleoproteins

2009 ◽  
Vol 72 (4) ◽  
pp. 616-627 ◽  
Author(s):  
Sérgio Mota ◽  
Marta Mendes ◽  
Natália Freitas ◽  
Deborah Penque ◽  
Ana V. Coelho ◽  
...  
Keyword(s):  
Cell Line ◽  
Hepatitis Delta Virus ◽  
Human Liver ◽  
Carcinoma Cell ◽  
Proteome Analysis ◽  
Carcinoma Cell Line ◽  
Liver Carcinoma ◽  
Hepatitis Delta ◽  
Delta Virus

Monofunctional Platinum Complexes Showing Potent Cytotoxicity against Human Liver Carcinoma Cell Line BEL-7402

2003 ◽  
Vol 46 (16) ◽  
pp. 3502-3507 ◽  
Author(s):  
Junyong Zhang ◽  
Xiaoyong Wang ◽  
Chao Tu ◽  
Jun Lin ◽  
Jian Ding ◽  
...  
Keyword(s):  
Cell Line ◽  
Human Liver ◽  
Carcinoma Cell ◽  
Platinum Complexes ◽  
Carcinoma Cell Line ◽  
Liver Carcinoma

Antiplasmodial and cytotoxic activities of two Euphorbiaceae family plants, Euphorbia hirta and Euphorbia thymifolia

2021 ◽  
Vol 17 ◽  
Author(s):  
Jigna Vadalia ◽  
Jalpa Sanandia ◽  
Vaibhav Bhatt ◽  
Navin Sheth
Keyword(s):  
Cell Line ◽  
Mtt Assay ◽  
Methanol Extract ◽  
Carcinoma Cell ◽  
Huh7 Cell ◽  
Carcinoma Cell Line ◽  
Liver Carcinoma ◽  
Cytotoxic Activities ◽  
Euphorbia Hirta

Background: Malaria is a major disease of developing countries and the main issue in its control of resistance against all available antimalarial drugs. Our aim is to find affordable therapy for this worldwide problem. The present study was conducted to evaluate the antiplasmodial and cytotoxic activities of Euphorbia hirta and Euphorbia thymifolia. Methods: The antiplasmodial activity was evaluated against chloroquine-sensitive (MRC-2) and chloroquine-resistant (RKL-9) strain of Plasmodium falciparum by schizont maturation inhibition and Plasmodium lactate dehydrogenase (PfLDH) activity assays. The cytotoxicity was performed by MTT assay on Huh7 liver carcinoma cell line. Results: IC50 for PfLDH activity of E. hirta and E. thymifolia methanol extract against P. faciparum MRC-2 strain was 9.6 and 12.6 µg/mL, respectively and against P. faciparum RKL-9 strain was 10.2 and 11.56 µg/mL, respectively. Methanol extract of E. thymifolia showed lower IC50 (19.3 µg/mL) than methanol extract of E. hirta (24.7 µg/mL) in MTT assay against Huh7 cell line. Conclusion: Both the plant methanol extracts showed a two-fold lower cytotoxic activity against hepatocyte derived carcinoma cell line (Huh7) compared to in vitro inhibitory activity against P. falciparum strains (MRC-2 and RKL-9).

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