New drug development during and after a period of regulatory change: Clinical research activity of major united states pharmacxeutical firms, 1958 to 1979

1983 ◽  
Vol 33 (6) ◽  
pp. 691-700 ◽  
Author(s):  
Maureen S May ◽  
William M Wardell ◽  
Louis Lasagna
Keyword(s):  
United States ◽  
Drug Development ◽  
Clinical Research ◽  
Regulatory Change ◽  
Research Activity ◽  
New Drug ◽  
Clinical Research Activity ◽  
New Drug Development

The Effect of Price on Pharmaceutical R&D

2009 ◽  
Vol 9 (1) ◽  
Author(s):  
Abdulkadir Civan ◽  
Michael T. Maloney
Keyword(s):  
United States ◽  
Drug Development ◽  
Price Elasticity ◽  
The United States ◽  
Mortality Rates ◽  
New Drugs ◽  
New Drug ◽  
Development Pipeline ◽  
New Drug Development

Abstract This work extends prior research that finds drug development is driven by demand factors such as mortality rates of the diseases new drugs are aimed at. Here we find that the number of drugs in the development pipeline is strongly positively related to the price of existing drugs treating those diseases. This gives us a direct price elasticity measure from which we can draw some inference about the effect on new drug development that might occur if the pricing regime in the United States were to change.

New drug development in the United States, 1963 through 1984

1988 ◽  
Vol 43 (3) ◽  
pp. 290-301 ◽  
Author(s):  
Nancy Mattison ◽  
A Gene Trimble ◽  
Louis Lasagna
Keyword(s):  
United States ◽  
Drug Development ◽  
The United States ◽  
New Drug ◽  
New Drug Development

New drug development in the United States from 1963 to 1992

1994 ◽  
Vol 55 (6) ◽  
pp. 609-622 ◽  
Author(s):  
Joseph A DiMasi ◽  
Mark A Seibring ◽  
Louis Lasagna
Keyword(s):  
United States ◽  
Drug Development ◽  
The United States ◽  
New Drug ◽  
New Drug Development

New drug development in the United States from 1963 to 1990

1991 ◽  
Vol 50 (5/1) ◽  
pp. 471-486 ◽  
Author(s):  
Joseph A DiMasi ◽  
Natalie R Bryant ◽  
Louis Lasagna
Keyword(s):  
United States ◽  
Drug Development ◽  
The United States ◽  
New Drug ◽  
New Drug Development
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