scholarly journals Silencing FLI or targeting CD13/ANPEP lead to dephosphorylation of EPHA2, a mediator of BRAF inhibitor resistance, and induce growth arrest or apoptosis in melanoma cells

2017 ◽  
Vol 8 (8) ◽  
pp. e3029-e3029 ◽  
Author(s):  
Alireza Azimi ◽  
Rainer Tuominen ◽  
Fernanda Costa Svedman ◽  
Stefano Caramuta ◽  
Maria Pernemalm ◽  
...  
Keyword(s):  
Growth Arrest ◽  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Inhibitor Resistance ◽  
Induce Growth Arrest

scholarly journals Rho-mediated signaling promotes BRAF inhibitor resistance in de-differentiated melanoma cells

Oncogene ◽  
2019 ◽  
Vol 39 (7) ◽  
pp. 1466-1483 ◽  
Author(s):  
S. A. Misek ◽  
K. M. Appleton ◽  
T. S. Dexheimer ◽  
E. M. Lisabeth ◽  
R. S. Lo ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Inhibitor Resistance

scholarly journals Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP / TAZ activation

2015 ◽  
Vol 35 (5) ◽  
pp. 462-478 ◽  
Author(s):  
Min Hwan Kim ◽  
Jongshin Kim ◽  
Hyowon Hong ◽  
Si‐Hyung Lee ◽  
June‐Koo Lee ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Actin Remodeling ◽  
Inhibitor Resistance

scholarly journals PDGFRα up-regulation mediated by sonic hedgehog pathway activation leads to BRAF inhibitor resistance in melanoma cells with BRAF mutation

Oncotarget ◽  
2014 ◽  
Vol 5 (7) ◽  
pp. 1926-1941 ◽  
Author(s):  
Francesco Sabbatino ◽  
Yangyang Wang ◽  
Xinhui Wang ◽  
Keith T. Flaherty ◽  
Ling Yu ◽  
...  
Keyword(s):  
Sonic Hedgehog ◽  
Braf Mutation ◽  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Hedgehog Pathway ◽  
Sonic Hedgehog Pathway ◽  
Pathway Activation ◽  
Inhibitor Resistance

scholarly journals PTEN Loss Confers BRAF Inhibitor Resistance to Melanoma Cells through the Suppression of BIM Expression

2011 ◽  
Vol 71 (7) ◽  
pp. 2750-2760 ◽  
Author(s):  
Kim H.T. Paraiso ◽  
Yun Xiang ◽  
Vito W. Rebecca ◽  
Ethan V. Abel ◽  
Y. Ann Chen ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Pten Loss ◽  
Inhibitor Resistance

Abstract 5370: PTEN loss confers BRAF inhibitor resistance to melanoma cells through the suppression of BIM expression

2011 ◽  
Author(s):  
Kim H. Paraiso ◽  
Vito Rebecca ◽  
Inna V. Fedorenko ◽  
Yun Xiang ◽  
Elizabeth Wood ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Pten Loss ◽  
Inhibitor Resistance

scholarly journals The anti-apoptotic BAG3 protein is involved in BRAF inhibitor resistance in melanoma cells

Oncotarget ◽  
2017 ◽  
Vol 8 (46) ◽  
pp. 80393-80404 ◽  
Author(s):  
Luana Guerriero ◽  
Giuseppe Palmieri ◽  
Margot De Marco ◽  
Antonio Cossu ◽  
Paolo Remondelli ◽  
...  
Keyword(s):  
Braf Inhibitor ◽  
Melanoma Cells ◽  
Inhibitor Resistance
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