scholarly journals Increased expression of EHF via gene amplification contributes to the activation of HER family signaling and associates with poor survival in gastric cancer

2016 ◽  
Vol 7 (10) ◽  
pp. e2442-e2442 ◽  
Author(s):  
Jing Shi ◽  
Yiping Qu ◽  
Xinru Li ◽  
Fang Sui ◽  
Demao Yao ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gene Amplification ◽  
Poor Survival ◽  
Her Family

scholarly journals FGFR2 in gastric cancer: protein overexpression predicts gene amplification and high H-index predicts poor survival

2016 ◽  
Vol 29 (9) ◽  
pp. 1095-1103 ◽  
Author(s):  
Soomin Ahn ◽  
Jeeyun Lee ◽  
Mineui Hong ◽  
Seung Tae Kim ◽  
Se Hoon Park ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Gene Amplification ◽  
Protein Overexpression ◽  
Poor Survival ◽  
H Index

A PILOT STUDY OF HER-2/NEU GENE AMPLIFICATION ASSESSED BY FLUORESCENCE IN SITU HYBRIDIZATION (FISH) IN GASTRIC CANCER

2014 ◽  
pp. 15-20
Author(s):  
Van Huy Tran ◽  
Thi Minh Thi Ha ◽  
Trung Nghia Van ◽  
Viet Nhan Nguyen ◽  
Phan Tuong Quynh Le ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
In Situ Hybridization ◽  
Fluorescence In Situ Hybridization ◽  
Cancer Patients ◽  
Gene Amplification ◽  
Cancer Tissue ◽  
Tissue Samples ◽  
Her 2 ◽  
Gastric Cancer Patients

Background: HER-2/neu is a predictive biomarker for treatment of gastric cancer using trastuzumab in combination with chemotherapy. This study aimed to evaluate the status of HER-2/neu gene amplification using fluorescence in situ hybridization (FISH) in gastric cancer. Patients and methods: thirty six gastric cancer patients were assessed HER-2/neu gene amplification by FISH using PathVysionTM HER-2 DNA Probe kit (including HER-2/neu probe and CEP-17 probe) with biopsy and surgical specimens. Results: The HER-2/neu gene amplification was observed in three cases (8.3%), the HER-2/neu gene amplification rate in Lauren’s intestinal-type and diffuse-type were 11.8% and 5.2%, respectively. Conclusion: We applied successfully FISH technique with gastric cancer tissue samples. This technique could be performed as routine test in gastric cancer in order to select patients that benefit from trastuzumab in combination with chemotherapy.

scholarly journals MET overexpression assessed by new interpretation method predicts gene amplification and poor survival in advanced gastric carcinomas

2013 ◽  
Vol 26 (12) ◽  
pp. 1632-1641 ◽  
Author(s):  
Sang Y Ha ◽  
Jeeyun Lee ◽  
So Y Kang ◽  
In-Gu Do ◽  
Soomin Ahn ◽  
...  
Keyword(s):  
Gene Amplification ◽  
Poor Survival ◽  
Gastric Carcinomas ◽  
New Interpretation ◽  
Interpretation Method

Loss of LINC01939 expression predicts progression and poor survival in gastric cancer

2018 ◽  
Vol 214 (10) ◽  
pp. 1539-1543 ◽  
Author(s):  
Chun-Li Chen ◽  
Qing Ke ◽  
Ming Luo ◽  
Zi-Ye Gao ◽  
Zhi-Jiu Li ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Poor Survival

scholarly journals Allelic Imbalance of 8p Indicates Poor Survival in Gastric Cancer

2004 ◽  
Vol 6 (3) ◽  
pp. 243-252 ◽  
Author(s):  
Amy J. French ◽  
Gina Petroni ◽  
Stephen N. Thibideau ◽  
Mark Smolkin ◽  
Eric Bissonette ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Allelic Imbalance ◽  
Poor Survival

scholarly journals HER-Family Ligands Promote Acquired Resistance to Trastuzumab in Gastric Cancer

2019 ◽  
Vol 18 (11) ◽  
pp. 2135-2145 ◽  
Author(s):  
Aïda Sampera ◽  
Francisco Javier Sánchez-Martín ◽  
Oriol Arpí ◽  
Laura Visa ◽  
Mar Iglesias ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Acquired Resistance ◽  
Her Family
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