scholarly journals Mutation of a Nopp140 gene dao-5 alters rDNA transcription and increases germ cell apoptosis in C. elegans

2014 ◽  
Vol 5 (4) ◽  
pp. e1158-e1158 ◽  
Author(s):  
C-C Lee ◽  
Y-T Tsai ◽  
C-W Kao ◽  
L-W Lee ◽  
H-J Lai ◽  
...  
Keyword(s):  
Germ Cell ◽  
Cell Apoptosis ◽  
Rdna Transcription ◽  
Germ Cell Apoptosis ◽  
C Elegans

scholarly journals The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegans

2011 ◽  
Vol 18 (7) ◽  
pp. 1140-1149 ◽  
Author(s):  
A J Ross ◽  
M Li ◽  
B Yu ◽  
M X Gao ◽  
W B Derry
Keyword(s):  
Dna Damage ◽  
Germ Cell ◽  
Ubiquitin Ligase ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans

scholarly journals Isoflurane impairs oogenesis through germ cell apoptosis in C. elegans

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tao Zhang ◽  
Cheng Ni ◽  
Cheng Li ◽  
Pan Lu ◽  
Dan Chen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Germ Cell ◽  
Fluorescence Imaging ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans ◽  
Interaction Studies ◽  
Acetyl Cysteine ◽  
Induced Changes ◽  
And Oxidative Stress

AbstractAnesthetic isoflurane has been reported to induce toxicity. However, the effects of isoflurane on fecundity remain largely unknown. We established a system in C. elegans to investigate the effects of isoflurane on oogenesis. Synchronized L4 stage C. elegans were treated with 7% isoflurane for 4 h. Dead cells, ROS, embryos, and unfertilized eggs laid by hermaphrodites were measured by fluorescence imaging and counting. The C. elegans with losses of ced-3, cep-1, abl-1, male C. elegans, and oxidative stress inhibitor N-acetyl-cysteine were used in the interaction studies. We found that isoflurane decreased the numbers of embryos and unfertilized eggs and increased the levels of dead cells and ROS in C. elegans. The isoflurane-induced impairment of oogenesis was associated with abl-1, ced-3, but not cep-1. N-acetyl-cysteine attenuated the isoflurane-induced impairment of oogenesis in C. elegans. Mating with male C. elegans did not attenuate the isoflurane-induced changes in oogenesis. These findings suggest that isoflurane may impair oogenesis through abl-1- and ced-3-associated, but not cep-1-associated, germ cell apoptosis and oxidative stress, pending further investigation. These studies will promote more research to determine the potential effects of anesthesia on fecundity.

scholarly journals Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

2004 ◽  
Vol 11 (11) ◽  
pp. 1198-1203 ◽  
Author(s):  
G Lettre ◽  
E A Kritikou ◽  
M Jaeggi ◽  
A Calixto ◽  
A G Fraser ◽  
...  
Keyword(s):  
Germ Cell ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans ◽  
Genome Wide

scholarly journals In search of proteins that regulated starvation-induced germ cell apoptosis in C. elegans

2007 ◽  
Vol 306 (1) ◽  
pp. 383
Author(s):  
Carlos G. Silva ◽  
Jorge Ramirez ◽  
Rosa E. Navarro
Keyword(s):  
Germ Cell ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans

scholarly journals Cap-Independent Translation Promotes C. elegans Germ Cell Apoptosis through Apaf-1/CED-4 in a Caspase-Dependent Mechanism

PLoS ONE ◽  
2011 ◽  
Vol 6 (9) ◽  
pp. e24444 ◽  
Author(s):  
Vince Contreras ◽  
Andrew J. Friday ◽  
J. Kaitlin Morrison ◽  
Enhui Hao ◽  
Brett D. Keiper
Keyword(s):  
Germ Cell ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans ◽  
Independent Translation ◽  
Dependent Mechanism

scholarly journals Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans

PLoS Genetics ◽  
2019 ◽  
Vol 15 (5) ◽  
pp. e1008150 ◽  
Author(s):  
Hyemin Min ◽  
Yong-Uk Lee ◽  
Yhong-Hee Shim ◽  
Ichiro Kawasaki
Keyword(s):  
Dna Damage ◽  
Germ Cell ◽  
Cell Apoptosis ◽  
Germ Cell Apoptosis ◽  
C Elegans

Bcl-2 and Bax are involved in experimental cryptorchidism-induced testicular germ cell apoptosis in rhesus monkey

Contraception ◽  
2003 ◽  
Vol 68 (4) ◽  
pp. 297-301 ◽  
Author(s):  
Zhi-Hong Zhang ◽  
Xuan Jin ◽  
Xue-Sen Zhang ◽  
Zhao-Yuan Hu ◽  
Ru-Jin Zou ◽  
...  
Keyword(s):  
Rhesus Monkey ◽  
Germ Cell ◽  
Cell Apoptosis ◽  
Testicular Germ Cell ◽  
Germ Cell Apoptosis
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