scholarly journals Parathyroid hormone reflects adiposity and cardiometabolic indices but not bone density in normal men

2016 ◽  
Vol 5 ◽  
Author(s):  
Emma O Billington ◽  
Greg D Gamble ◽  
Ian R Reid
1990 ◽  
Vol 71 (6) ◽  
pp. 1556-1560 ◽  
Author(s):  
F. C. LOGUE ◽  
W. D. FRASER ◽  
D. ST. J. O'REILLY ◽  
D. A. CAMERON ◽  
A. J. KELLY ◽  
...  

2014 ◽  
Vol 17 ◽  
pp. 19568 ◽  
Author(s):  
Amanda Samarawickrama ◽  
Sophie Jose ◽  
Caroline Sabin ◽  
Karen Walker-Bone ◽  
Martin Fisher ◽  
...  

2010 ◽  
Vol 54 (2) ◽  
pp. 213-219 ◽  
Author(s):  
Victória Z. Cochenski Borba ◽  
Nádila Cecyn Pietszkowski Mañas

Anabolic drugs have recently widened therapeutic options in osteoporosis treatment, as they influence processes associated with bone formation to a greater extent and earlier than bone reabsortion. They positively affect a number of skeletal properties besides bone density, as intermittent administration of parathyroid hormone (PTH) results in an increase in the number and activity of osteoblasts leading to an increase in bone mass and improvement in skeletal architecture at both the trabecular and cortical bone. Human recombinant parathyroid hormone (hrPTH 1-84) and human recombinant PTH peptide 1-34 (teriparatide) belong to this group. The objective of this paper is to review PTH actions, benefits and adverse effects, action on biochemical markers, combination therapy with antiresorptive agents, impact of antiresorptive therapy prior to anabolic treatment, sequential treatment, and effect on glucocorticoid-induced osteoporosis.


1989 ◽  
Vol 121 (1) ◽  
pp. R1-R3 ◽  
Author(s):  
F.C. Logue ◽  
W.D. Fraser ◽  
D.St.J. O'Reilly ◽  
G.H. Beastall

ABSTRACT A pronounced circadian rhythm has been demonstrated for intact parathyroid hormone (1-84) in the serum of normal male adults. The broad nocturnal rise of parathyroid hormone (1-84) secretion appears to be of physiological significance, for it is accompanied by a significant rise in nephrogenous cyclic adenosine monophosphate. The rate of return of parathyroid hormone (1-84) to baseline concentrations varies between individuals, an observation which has implications for the optimal time of sampling for the investigation of possible mild hyperparathyroidism.


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