scholarly journals Intramembranous bone regeneration and implant placement using mechanical femoral marrow ablation: rodent models

2016 ◽  
Vol 5 ◽  
Author(s):  
Meghan M Moran ◽  
Kotaro Sena ◽  
Margaret A McNulty ◽  
D R Sumner ◽  
Amarjit S Virdi
Keyword(s):  
Bone Regeneration ◽  
Rodent Models ◽  
Implant Placement ◽  
Intramembranous Bone ◽  
Marrow Ablation

Intramembranous bone regeneration differs among common inbred mouse strains following marrow ablation

2015 ◽  
Vol 33 (9) ◽  
pp. 1374-1381 ◽  
Author(s):  
Meghan M. Moran ◽  
Amarjit S. Virdi ◽  
Kotaro Sena ◽  
Steven R. Mazzone ◽  
Margaret A. McNulty ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Inbred Mouse ◽  
Mouse Strains ◽  
Inbred Mouse Strains ◽  
Intramembranous Bone ◽  
Marrow Ablation

Patterns and Localization of Gene Expression During Intramembranous Bone Regeneration in the Rat Femoral Marrow Ablation Model

2005 ◽  
Vol 77 (4) ◽  
pp. 212-225 ◽  
Author(s):  
Shinji Kuroda ◽  
Amarjit S. Virdi ◽  
Yang Dai ◽  
Susan Shott ◽  
Dale R. Sumner
Keyword(s):  
Gene Expression ◽  
Bone Regeneration ◽  
Intramembranous Bone ◽  
Marrow Ablation ◽  
Ablation Model

scholarly journals Temporal Gene Expression Profiling during Rat Femoral Marrow Ablation-Induced Intramembranous Bone Regeneration

PLoS ONE ◽  
2010 ◽  
Vol 5 (10) ◽  
pp. e12987 ◽  
Author(s):  
Joel K. Wise ◽  
Kotaro Sena ◽  
Karen Vranizan ◽  
Jacob F. Pollock ◽  
Kevin E. Healy ◽  
...  
Keyword(s):  
Gene Expression ◽  
Bone Regeneration ◽  
Gene Expression Profiling ◽  
Expression Profiling ◽  
Temporal Gene Expression ◽  
Intramembranous Bone ◽  
Marrow Ablation

scholarly journals Notch-Wnt signal crosstalk regulates proliferation and differentiation of osteoprogenitor cells during intramembranous bone healing

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
S. Lee ◽  
L. H. Remark ◽  
A. M. Josephson ◽  
K. Leclerc ◽  
E. Muiños Lopez ◽  
...  
Keyword(s):  
Wnt Signaling ◽  
Notch Signaling ◽  
Bone Regeneration ◽  
Bone Healing ◽  
Canonical Wnt Signaling ◽  
Osteoprogenitor Cells ◽  
Intramembranous Bone ◽  
Proliferation And Differentiation ◽  
Canonical Wnt ◽  
Wnt Signal

AbstractAdult bone regeneration is orchestrated by the precise actions of osteoprogenitor cells (OPCs). However, the mechanisms by which OPC proliferation and differentiation are linked and thereby regulated are yet to be defined. Here, we present evidence that during intramembranous bone formation OPC proliferation is controlled by Notch signaling, while differentiation is initiated by activation of canonical Wnt signaling. The temporospatial separation of Notch and Wnt signal activation during the early stages of bone regeneration suggests crosstalk between the two pathways. In vitro and in vivo manipulation of the two essential pathways demonstrate that Wnt activation leads to initiation of osteogenic differentiation and at the same time inhibits Notch signaling, which results in termination of the proliferative phase. Here, we establish canonical Wnt signaling as a key regulator that facilitates the crosstalk between OPC proliferation and differentiation during intramembranous, primary bone healing.

Guided bone regeneration for immediate non-submerged implant placement using bioabsorbable materials in Beagle dogs

1998 ◽  
Vol 9 (5) ◽  
pp. 303-312 ◽  
Author(s):  
Gérard Brunel ◽  
Edmond Benqué ◽  
Frédéric Elharar ◽  
Catherine Sansac ◽  
Jean François Duffort ◽  
...  
Keyword(s):  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Beagle Dogs ◽  
Implant Placement

scholarly journals Management of Retrograde Peri-Implantitis Using an Air-Abrasive Device, Er,Cr:YSGG Laser, and Guided Bone Regeneration

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
Nikolaos Soldatos ◽  
Georgios E. Romanos ◽  
Michelle Michaiel ◽  
Ali Sajadi ◽  
Nikola Angelov ◽  
...  
Keyword(s):  
Case Report ◽  
Bone Density ◽  
Bone Regeneration ◽  
Guided Bone Regeneration ◽  
Etiologic Factor ◽  
Ridge Preservation ◽  
X Rays ◽  
Case Description ◽  
Implant Placement ◽  
Maxillary Molar

Background. The placement of an implant in a previously infected site is an important etiologic factor contributing to implant failure. The aim of this case report is to present the management of retrograde peri-implantitis (RPI) in a first maxillary molar site, 2 years after the implant placement. The RPI was treated using an air-abrasive device, Er,Cr:YSGG laser, and guided bone regeneration (GBR). Case Description. A 65-year-old Caucasian male presented with a draining fistula associated with an implant at tooth #3. Tooth #3 revealed periapical radiolucency two years before the implant placement. Tooth #3 was extracted, and a ridge preservation procedure was performed followed by implant rehabilitation. A periapical radiograph (PA) showed lack of bone density around the implant apex. The site was decontaminated with an air-abrasive device and Er,Cr:YSGG laser, and GBR was performed. The patient was seen every two weeks until suture removal, followed by monthly visits for 12 months. The periapical X-rays, from 6 to 13 months postoperatively, showed increased bone density around the implant apex, with no signs of residual clinical or radiographic pathology and probing depths ≤4 mm. Conclusions. The etiology of RPI in this case was the placement of an implant in a previously infected site. The use of an air-abrasive device, Er,Cr:YSGG, and GBR was utilized to treat this case of RPI. The site was monitored for 13 months, and increased radiographic bone density was noted.

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