scholarly journals Depression and anxiety following hematopoietic stem cell transplantation: a prospective population-based study in Germany

2017 ◽  
Vol 52 (12) ◽  
pp. 1651-1657 ◽  
Author(s):  
K Kuba ◽  
P Esser ◽  
A Mehnert ◽  
C Johansen ◽  
A Schwinn ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Population Based ◽  
Depression And Anxiety ◽  
Population Based Study ◽  
Hematopoietic Stem

scholarly journals Mindfulness, Experiential Avoidance, and Recovery From Hematopoietic Stem Cell Transplantation

2019 ◽  
Vol 53 (10) ◽  
pp. 886-895 ◽  
Author(s):  
Anna G Larson ◽  
Keayra J Morris ◽  
Mark B Juckett ◽  
Christopher L Coe ◽  
Aimee T Broman ◽  
...  
Keyword(s):  
Stem Cell ◽  
Hematopoietic Stem Cell Transplantation ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Hematopoietic Stem Cell ◽  
Physical Functioning ◽  
Experiential Avoidance ◽  
Present Moment ◽  
Depression And Anxiety ◽  
Hematopoietic Stem

AbstractBackgroundMood disturbance, pain, and fatigue are prevalent and distressing concerns for patients with hematologic cancer recovering from hematopoietic stem cell transplantation (HSCT). The way in which individuals approach difficult thoughts and emotions may affect symptoms and functioning. Specifically, mindfulness has been associated with more optimal psychological and physical functioning, whereas experiential avoidance has been associated with poorer outcomes.PurposeThe primary objective was to determine whether mindfulness and experiential avoidance measured prior to HSCT were associated with recovery of psychological and physical functioning following HSCT. We also evaluated dimensions of mindfulness to determine which were most robustly associated with outcomes.MethodsParticipants completed measures of mindfulness and experiential avoidance prior to HSCT. Depression and anxiety symptoms and pain and fatigue interference with daily activities were assessed prior to HSCT and 1, 3, and 6 months post-HSCT.ResultsParticipants who reported better ability to describe their internal experiences and who were better able to act with awareness experienced less depression, anxiety, and fatigue interference following HSCT. Participants who were nonjudgmental and nonreactive toward thoughts and emotions experienced less depression and anxiety following HSCT, but these traits were not associated with pain or fatigue interference. Being a good observer of internal experiences was not associated with outcomes, nor was experiential avoidance.ConclusionsResults suggest that most facets of mindfulness may optimize psychological functioning following HSCT, and the ability to describe one’s internal experience and to focus on the present moment may have a beneficial influence on physical functioning.

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