scholarly journals Tenascin C in colorectal cancer stroma is a predictive marker for liver metastasis and is a potent target of miR-198 as identified by microRNA analysis

2017 ◽  
Vol 117 (9) ◽  
pp. 1360-1370 ◽  
Author(s):  
Tomohiro Murakami ◽  
Hirotoshi Kikuchi ◽  
Hisato Ishimatsu ◽  
Ichirota Iino ◽  
Amane Hirotsu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Predictive Marker ◽  
Tenascin C ◽  
Cancer Stroma

Abstract 4028: Tenascin C in gastric cancer stroma is a predictive marker for postoperative prognosis

2019 ◽  
Author(s):  
Hirotoshi Kikuchi ◽  
Tomohiro Murakami ◽  
Sanshiro Kawata ◽  
Amane Hirotsu ◽  
Tomohiro Matsumoto ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Predictive Marker ◽  
Postoperative Prognosis ◽  
Tenascin C ◽  
Cancer Stroma

scholarly journals Diabetes mellitus is associated with liver metastasis of colorectal cancer through production of biglycan-rich cancer stroma

Oncotarget ◽  
2020 ◽  
Vol 11 (31) ◽  
pp. 2982-2994 ◽  
Author(s):  
Rina Fujiwara-Tani ◽  
Takamitsu Sasaki ◽  
Kiyomu Fujii ◽  
Yi Luo ◽  
Takuya Mori ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Cancer Stroma

Abstract 4028: Tenascin C in gastric cancer stroma is a predictive marker for postoperative prognosis

2019 ◽  
Author(s):  
Hirotoshi Kikuchi ◽  
Tomohiro Murakami ◽  
Sanshiro Kawata ◽  
Amane Hirotsu ◽  
Tomohiro Matsumoto ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Predictive Marker ◽  
Postoperative Prognosis ◽  
Tenascin C ◽  
Cancer Stroma

Increased Osteopontin-Positive Macrophage Expression in Colorectal Cancer Stroma with Synchronous Liver Metastasis

2010 ◽  
Vol 34 (8) ◽  
pp. 1930-1936 ◽  
Author(s):  
Motohiro Imano ◽  
Kiyokata Okuno ◽  
Tatsuki Itoh ◽  
Eizaburo Ishimaru ◽  
Takao Satou ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Synchronous Liver Metastasis ◽  
Cancer Stroma

Progastrin: a potential predictive marker of liver metastasis in colorectal cancer

2017 ◽  
Vol 32 (7) ◽  
pp. 1061-1064 ◽  
Author(s):  
David A Westwood ◽  
Oneel Patel ◽  
Christopher Christophi ◽  
Arthur Shulkes ◽  
Graham S Baldwin
Keyword(s):  
Colorectal Cancer ◽  
Liver Metastasis ◽  
Predictive Marker

Neutrophil/lymphocyte Ratio after Flow Citometry Periferic Blood Cell Detection - Predictive Marker of Anastomotic Fistula in Colorectal Cancer Surgery

2020 ◽  
Vol 71 (6) ◽  
pp. 295-306
Author(s):  
Dumitru Radulescu ◽  
Vlad Dumitru Baleanu ◽  
Andrei Nicolaescu ◽  
Marius Lazar ◽  
Marius Bica ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Rectal Surgery ◽  
Predictive Marker ◽  
Fistula Formation ◽  
Cell Detection ◽  
Colon And Rectal Surgery ◽  
Optimal Value ◽  
Anastomotic Fistula ◽  
Colorectal Cancer Patients

Anastomotic fistula is a dreadful complication of colon and rectal surgery that can put life into danger, being common after colorectal surgery. The preoperative lymphocyte neutrophil ratio (NLR) is known as a prognostic marker for colorectal cancer patients. The existence of a predictive marker of anastomotic fistula in colorectal cancer patients is not fully undestood, so we proposed to investigate the utility of preoperative NLR as a predictor of anastomotic fistula formation. This study the Neutrophils and lymphocytes were detected from periferic blood using flow citometry. We retrospectively evaluated 161 patients with colorectal cancer, who were treated curatively, in which at least one anastomosis was performed, comparing NLR values between patients who had fistula and those with normal healing, then comparing the group with low NLR, with the group with increased NLR, after finding the optimal value of NLR using the ROC curve.The optimal value of the NLR after establishing the cutoff value was 3.07. Between the low NLR group (n=134) and the high NLR group (n=27), were observed statistically significant differences in fistula (p [0.001) and death (p=0.001). The odds ratio for failure in the group with increased NLR was 10.37, which means that patients with NLR]3.54 have a chance of developing anastomotic fistula greater than 10.37 comparable to patients with lower NLR. We suggest the preoperative use of NLR can be used as a predictive marker of anastomotic fistula than can increase the quality of preoperative preparation and therefore the establishment of the optimal surgical technique that can lead to anastomotic fistula risk decrease.

Sign in / Sign up

Export Citation Format

Share Document