scholarly journals Validation of the prognostic relevance of plasma C-reactive protein levels in soft-tissue sarcoma patients

2013 ◽  
Vol 109 (9) ◽  
pp. 2316-2322 ◽  
Author(s):  
J Szkandera ◽  
A Gerger ◽  
B Liegl-Atzwanger ◽  
G Absenger ◽  
M Stotz ◽  
...  
2013 ◽  
Vol 49 (2) ◽  
pp. 377-385 ◽  
Author(s):  
Tomoki Nakamura ◽  
Robert Grimer ◽  
Czar Gaston ◽  
Matthew Francis ◽  
Jackie Charman ◽  
...  

Cancer ◽  
2011 ◽  
Vol 118 (4) ◽  
pp. 1055-1061 ◽  
Author(s):  
Tomoki Nakamura ◽  
Akihiko Matsumine ◽  
Takao Matsubara ◽  
Kunihiro Asanuma ◽  
Astumasa Uchida ◽  
...  

Oncotarget ◽  
2017 ◽  
Vol 8 (58) ◽  
pp. 98135-98147 ◽  
Author(s):  
Yao Liang ◽  
Wei Xiao ◽  
Yuan-Xiang Guan ◽  
Wei Wang ◽  
Huo Ying Chen ◽  
...  

Tumor Biology ◽  
2015 ◽  
Vol 36 (10) ◽  
pp. 7515-7520 ◽  
Author(s):  
Tomoki Nakamura ◽  
Akihiko Matsumine ◽  
Kunihiro Asanuma ◽  
Takao Matsubara ◽  
Akihiro Sudo

VASA ◽  
2015 ◽  
Vol 44 (3) ◽  
pp. 0187-0194 ◽  
Author(s):  
Xiaoni Chang ◽  
Jun Feng ◽  
Litao Ruan ◽  
Jing Shang ◽  
Yanqiu Yang ◽  
...  

Background: Neovascularization is one of the most important risk factors for unstable plaque. This study was designed to correlate plaque thickness, artery stenosis and levels of serum C-reactive protein with the degree of intraplaque enhancement determined by contrast-enhanced ultrasound. Patients and methods: Contrast-enhanced ultrasound was performed on 72 carotid atherosclerotic plaques in 48 patients. Contrast enhancement within the plaque was categorized as grade 1, 2 or 3. Maximum plaque thickness was measured in short-axis view. Carotid artery stenosis was categorized as mild, moderate or severe. Results: Plaque contrast enhancement was not associated with the degree of artery stenosis or with plaque thickness. Serum C-reactive protein levels were positively correlated with the number of new vessels in the plaque. C-reactive protein levels increased in the three groups(Grade 1: 3.72±1.79mg/L; Grade 2: 7.88±4.24 mg/L; Grade 3: 11.02±3.52 mg/L), with significant differences among them (F=10.14, P<0.01), and significant differences between each two groups (P<0.05). Spearman’s rank correlation analysis showed that serum C-reactive protein levels were positively correlated with the degree of carotid plaque enhancement (Rs =0.69, P<0.01). Conclusions: The combination of C-reactive protein levels and intraplaque neovascularization detected by contrast-enhanced ultrasound may allow more accurate evaluation of plaque stability.


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