scholarly journals Cost-effectiveness of population-based screening for colorectal cancer: a comparison of guaiac-based faecal occult blood testing, faecal immunochemical testing and flexible sigmoidoscopy

2012 ◽  
Vol 106 (5) ◽  
pp. 805-816 ◽  
Author(s):  
L Sharp ◽  
L Tilson ◽  
S Whyte ◽  
A O'Ceilleachair ◽  
C Walsh ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cost Effectiveness ◽  
Flexible Sigmoidoscopy ◽  
Occult Blood ◽  
Population Based ◽  
Faecal Occult Blood Testing ◽  
Blood Testing ◽  
Faecal Occult Blood ◽  
Faecal Occult

Adherence to and predictors of participation in colorectal cancer screening with faecal occult blood testing in Spain, 2009–2011

2015 ◽  
Vol 24 (4) ◽  
pp. 305-312 ◽  
Author(s):  
Isa Ricardo-Rodrigues ◽  
Rodrigo Jiménez-García ◽  
Valentín Hernández-Barrera ◽  
Pilar Carrasco-Garrido ◽  
Isabel Jiménez-Trujillo ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Screening ◽  
Colorectal Cancer Screening ◽  
Occult Blood ◽  
Faecal Occult Blood Testing ◽  
Blood Testing ◽  
Faecal Occult Blood ◽  
Faecal Occult

scholarly journals Cost Analysis in a Population Based Screening Programme for Colorectal Cancer: Comparison of Immunochemical and Guaiac Faecal Occult Blood Testing

1997 ◽  
Vol 4 (3) ◽  
pp. 142-146 ◽  
Author(s):  
G Castiglione ◽  
M Zappa ◽  
G Grazzini ◽  
C Sani ◽  
A Mazzotta ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Screening Programme ◽  
Cost Effective ◽  
Occult Blood ◽  
Recall Rate ◽  
Population Based ◽  
Faecal Occult Blood Testing ◽  
Faecal Occult Blood ◽  
Blood Tests ◽  
Faecal Occult

Objective— To compare the costs of colorectal cancer (CRC) screening by two faecal occult blood tests (FOBT)—namely, Hemoccult (guaiac based) and reversed passive haemagglutination (RPHA) tests. RPHA was interpreted according to two positivity thresholds (+ or +/-). Methods— Attenders performed both tests. Subjects with a positive FOBT test were invited to have a complete exploration of the colon. The total costs for every 10 000 screened subjects and costs for each unit of result (screened subject, or patient with adenoma/s or cancer detected) were calculated for both tests. Results— 8353 subjects were enrolled. A total of 2109 repeated screening after two years. RPHA(+ and +/-) showed the highest and RPHA(+) the lowest positivity rate at first screening. The Hemoccult positivity rate was highest at repeat screening. Total costs of screening by RPHA(+ and +/-) were highest as this method had the highest recall rate. Screening by RPHA(+) was the least costly. Costs for each screened subject were highest for RPHA(+ and +/-) and lowest for RPHA(+). Costs for each cancer detected were lowest for RPHA(+) and highest for Hemoccult or RPHA(+ and +/-) in subjects aged > 49 or < 50, respectively. Costs for subjects with detected adenoma/s of > 9 mm were lowest for RPHA(+ and +/-) and highest for Hemoccult. At repeat screening total costs of RPHA(+ and +/-) were lower than at first screening, whereas for each subject with cancer or adenoma/s costs were increased. Conclusions— Our data confirm that screening by RPHA is more cost effective than by Hemoccult.

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