scholarly journals Upregulated ankyrin repeat-rich membrane spanning protein contributes to tumour progression in cutaneous melanoma

2011 ◽  
Vol 104 (6) ◽  
pp. 982-988 ◽  
Author(s):  
Y H Liao ◽  
S M Hsu ◽  
H L Yang ◽  
M S Tsai ◽  
P H Huang
Keyword(s):  
Cutaneous Melanoma ◽  
Tumour Progression ◽  
Ankyrin Repeat ◽  
Membrane Spanning

Ankyrin repeat-rich membrane spanning/Kidins220 protein interacts with mammalian Septin 5

2010 ◽  
Vol 30 (2) ◽  
pp. 143-148 ◽  
Author(s):  
Han Jeong Park ◽  
Hwan-Woo Park ◽  
Shin-Jae Lee ◽  
Juan Carlos Arevalo ◽  
Young-Seok Park ◽  
...  
Keyword(s):  
Ankyrin Repeat ◽  
Membrane Spanning

scholarly journals Ankyrin Repeat-Rich Membrane Spanning Protein (Kidins220) Is Required for Neurotrophin and Ephrin Receptor-Dependent Dendrite Development

2012 ◽  
Vol 32 (24) ◽  
pp. 8263-8269 ◽  
Author(s):  
Y. Chen ◽  
W.-Y. Fu ◽  
J. P. K. Ip ◽  
T. Ye ◽  
A. K. Y. Fu ◽  
...  
Keyword(s):  
Ankyrin Repeat ◽  
Dendrite Development ◽  
Ephrin Receptor ◽  
Membrane Spanning

scholarly journals Impact of general anaesthesia in overall and disease-free survival compared to other types of anaesthesia in patients undergoing surgery for cutaneous melanoma: a systematic review and meta-analysis protocol

BMJ Open ◽  
2019 ◽  
Vol 9 (7) ◽  
pp. e027993
Author(s):  
Bruno Luís de Castro Araujo ◽  
Jadivan Leite de Oliveira ◽  
Flavia de Miranda Corrêa ◽  
Luis Eduardo Santos Fontes ◽  
Andreia Cristina de Melo ◽  
...  
Keyword(s):  
General Anaesthesia ◽  
Cutaneous Melanoma ◽  
Tumour Progression ◽  
Meta Analysis ◽  
Disease Free Survival ◽  
Risk Of Bias ◽  
Free Survival ◽  
Analyse Data ◽  
Disease Free

IntroductionCutaneous melanoma is an aggressive type of skin cancer. Anaesthetic agents may have an impact on the immune response, postoperative neurohumoral response and tumour progression. This systematic review aims to evaluate the impact of general anaesthesia on overall and disease-free survival compared with other types anaesthesia in patients undergoing surgery for cutaneous melanoma.Methods and analysisThe review will analyse data from controlled and observational studies of patients undergoing surgery for melanoma under general anaesthesia compared with other types of anaesthesia. The primary outcomes are overall survival and disease-free survival. The secondary outcomes are health-related quality of life, time to tumour progression, distant disease-free survival, time to treatment failure, cancer-specific survival, biochemical recurrence, return of intended oncological therapy, days alive and out of the hospital at 90 days, cost analysis and adverse events. A comprehensive literature search will be performed using the MEDLINE, EMBASE, Cochrane CENTRAL, Web of Science, LILACS and IBECS databases. Grey literature will also be searched. Risk of methodological bias will be assessed using The Cochrane Collaboration’s revised tool for assessing risk of bias in randomised trials (RoB 2.0) and the Newcastle–Ottawa scale. Two reviewers will independently assess the eligibility of studies and risk of bias; a third author will solve discrepancies. One author will perform data extraction and the other will check the process and data. Qualitative analysis will be carried out using all included studies. A meta-analysis using a random-effects model for pooled risk estimates will be carried out for the two main outcomes and for selected secondary outcomes if they conform to previously stated criteria. The GRADE approach will be used to summarise the quality of evidence.Ethics and disseminationEthics approval is not required as we analyse data from previously reported studies.PROSPERO registration numberCRD42018114918.

scholarly journals The Ankyrin Repeat-rich Membrane Spanning (ARMS)/Kidins220 Scaffold Protein Is Regulated by Activity-dependent Calpain Proteolysis and Modulates Synaptic Plasticity

2010 ◽  
Vol 285 (52) ◽  
pp. 40472-40478 ◽  
Author(s):  
Synphen H. Wu ◽  
Juan Carlos Arévalo ◽  
Veronika E. Neubrand ◽  
Hong Zhang ◽  
Ottavio Arancio ◽  
...  
Keyword(s):  
Synaptic Plasticity ◽  
Scaffold Protein ◽  
Ankyrin Repeat ◽  
Membrane Spanning ◽  
Activity Dependent

scholarly journals Ankyrin Repeat-rich Membrane Spanning/Kidins220 protein regulates dendritic branching and spine stabilityin vivo

2009 ◽  
Vol 69 (9) ◽  
pp. 547-557 ◽  
Author(s):  
Synphen H. Wu ◽  
Juan Carlos Arévalo ◽  
Federica Sarti ◽  
Lino Tessarollo ◽  
Wen-Biao Gan ◽  
...  
Keyword(s):  
Ankyrin Repeat ◽  
Dendritic Branching ◽  
Membrane Spanning

Reduced expression of p16 and p27 is correlated with tumour progression in cutaneous melanoma

Pathology ◽  
2007 ◽  
Vol 39 (6) ◽  
pp. 551-557 ◽  
Author(s):  
Amira Sanki ◽  
Wei Li ◽  
Marjorie Colman ◽  
Rooshdiya Z. Karim ◽  
John F. Thompson ◽  
...  
Keyword(s):  
Cutaneous Melanoma ◽  
Tumour Progression
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