scholarly journals Induction of DT-diaphorase by 1,2-dithiole-3-thiones in human tumour and normal cells and effect on anti-tumour activity of bioreductive agents

1998 ◽  
Vol 77 (8) ◽  
pp. 1241-1252 ◽  
Author(s):  
GP Doherty ◽  
MK Leith ◽  
X Wang ◽  
TJ Curphey ◽  
A Begleiter
Keyword(s):  
Human Tumour ◽  
Normal Cells ◽  
Anti Tumour Activity ◽  
Bioreductive Agents ◽  
Dt Diaphorase ◽  
Tumour Activity

Anti-tumour chemotherapy

1975 ◽  
Vol 13 (5) ◽  
pp. 17-19
Keyword(s):  
Acute Lymphoblastic Leukaemia ◽  
Lymphoblastic Leukaemia ◽  
Cytotoxic Drugs ◽  
Malignant Cells ◽  
Malignant Tumours ◽  
Normal Cells ◽  
Optimum Treatment ◽  
Anti Tumour Activity ◽  
Low Toxicity ◽  
Tumour Activity

Cytotoxic drugs administered in high dosage have a much greater effect on tumour cells than on normal cells.1 In recent years great advances have been made using combinations of cytotoxic drugs: combinations in high dosage given intermittently can often produce high anti-tumour activity with low toxicity and, during periods between treatment, the normal cells recover more rapidly than the malignant cells. Major successes have been achieved in acute lymphoblastic leukaemia in children2 and in lymphomas, particularly in Hodgkin’s disease3 and in Burkitt’s tumour. This article reviews chemotherapy in other malignant tumours. As optimum treatment schedules have not yet been developed in most of these diseases, dosages are not quoted, but references are given.

scholarly journals Human Tumour Immune Evasion via TGF-β Blocks NK Cell Activation but Not Survival Allowing Therapeutic Restoration of Anti-Tumour Activity

PLoS ONE ◽  
2011 ◽  
Vol 6 (9) ◽  
pp. e22842 ◽  
Author(s):  
Erica B. Wilson ◽  
Jehan J. El-Jawhari ◽  
Abbie L. Neilson ◽  
Geoffrey D. Hall ◽  
Alan A. Melcher ◽  
...  
Keyword(s):  
Immune Evasion ◽  
Cell Activation ◽  
Nk Cell ◽  
Human Tumour ◽  
Anti Tumour Activity ◽  
Tumour Activity

Synthesis and Anti – Tumour Activity of Novel Camptothecin – Bile Acid Analogues

2011 ◽  
Vol 8 (8) ◽  
pp. 698-703 ◽  
Author(s):  
Q.-Y. Li ◽  
Y. Gao ◽  
W. Qiu ◽  
Y.-G. Zu ◽  
L. Su ◽  
...  
Keyword(s):  
Bile Acid ◽  
Anti Tumour Activity ◽  
Tumour Activity

scholarly journals Potent anti‐angiogenesis and anti‐tumour activity of pegaptanib‐loaded tetrahedral DNA nanostructure

2019 ◽  
Vol 52 (5) ◽  
Author(s):  
Xueping Xie ◽  
Yuxin Zhang ◽  
Wenjuan Ma ◽  
Xiaoru Shao ◽  
Yuxi Zhan ◽  
...  
Keyword(s):  
Dna Nanostructure ◽  
Anti Tumour Activity ◽  
Tumour Activity

Anti-insulin-like growth factor 1 receptor antibody EM164 (murine AVE1642) exhibits anti-tumour activity alone and in combination with temozolomide against neuroblastoma

2010 ◽  
Vol 46 (18) ◽  
pp. 3251-3262 ◽  
Author(s):  
Birgit Geoerger ◽  
Jean-François Brasme ◽  
Estelle Daudigeos-Dubus ◽  
Paule Opolon ◽  
Corinne Venot ◽  
...  
Keyword(s):  
Growth Factor ◽  
Insulin Like Growth Factor ◽  
Receptor Antibody ◽  
Anti Tumour Activity ◽  
Tumour Activity

New polydentate Ru(III)-Salan complexes: Synthesis, characterization, anti-tumour activity and interaction with human serum proteins

2013 ◽  
Vol 394 ◽  
pp. 616-626 ◽  
Author(s):  
Cristina P. Matos ◽  
Andreia Valente ◽  
Fernanda Marques ◽  
Pedro Adão ◽  
M. Paula Robalo ◽  
...  
Keyword(s):  
Human Serum ◽  
Serum Proteins ◽  
Anti Tumour Activity ◽  
Tumour Activity ◽  
Human Serum Proteins
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