scholarly journals The relationship between tumour oxygenation determined by oxygen electrode measurements and magnetic resonance spectroscopy of the fluorinated 2-nitroimidazole SR-4554

1998 ◽  
Vol 77 (1) ◽  
pp. 65-70 ◽  
Author(s):  
EO Aboagye ◽  
RJ Maxwell ◽  
MR Horsman ◽  
AD Lewis ◽  
P Workman ◽  
...  
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Oxygen Electrode ◽  
Resonance Spectroscopy ◽  
Tumour Oxygenation ◽  
The Relationship

Thyroid Hormone Concentrations and Muscle Metabolism in Amenorrheic and Eumenorrheic Athletes

1998 ◽  
Vol 23 (3) ◽  
pp. 293-306 ◽  
Author(s):  
Vicki J. Harber ◽  
Stewart R. Petersen ◽  
Philip D. Chilibeck
Keyword(s):  
Thyroid Hormone ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Inorganic Phosphate ◽  
Plantar Flexion ◽  
Muscle Metabolism ◽  
Resonance Spectroscopy ◽  
Recovery Rates ◽  
Exercise Muscle ◽  
The Relationship

The relationship between resting thyroid hormone concentrations and exercise muscle metabolism was examined among eumenorrheic endurance-trained (n = 11), amenorrheic endurance-trained (n = 8), and eumenorrheic nonathletic (n = 13) subjects. Muscle metabolism was assessed with 31Phosphorous magnetic resonance spectroscopy by measuring changes in phosphocreatine (PCr), inorganic phosphate (Pi), and pH during plantar flexion exercise and recovery. All groups had similar Pi/PCr ratios and pH changes during exercise. Eumenorrheic endurance-trained subjects had faster recovery rates for PCr and Pi/PCr following exercise compared to the nonathletes (p < .05) and faster recovery rates for PCr compared to amenorrheic subjects (p < .05). Thyroxine (T4) and triiodothyronine (T3) levels were significantly lower in amenorrheic subjects compared to both eumenorrheic groups (p < .05). It was concluded that routine training enhances muscle metabolism, as measured by phosphate recovery kinetics. This enhancement was not evident in amenorrheic athletes with reduced T3 and T4 concentrations. Key words:31Phosphorous magnetic resonance spectroscopy, phosphocreatine, inorganic phosphate, T3, T4, females

scholarly journals Macromolecule suppressed GABA levels show no relationship with age in a pediatric sample

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Tiffany Bell ◽  
Mehak Stokoe ◽  
Ashley D. Harris
Keyword(s):  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Developmental Disorders ◽  
Aminobutyric Acid ◽  
Resonance Spectroscopy ◽  
Healthy Children ◽  
Inhibitory Neurotransmitter ◽  
Healthy Development ◽  
The Relationship ◽  
Brain Gaba

AbstractThe inhibitory neurotransmitter γ-Aminobutyric acid (GABA) plays a crucial role in cortical development. Therefore, characterizing changes in GABA levels during development has important implications for the study of healthy development and developmental disorders. Brain GABA levels can be measured non-invasively using GABA-edited magnetic resonance spectroscopy (MRS). However, the most commonly used editing technique to measure GABA results in contamination of the GABA signal with macromolecules (MM). Therefore, GABA measured using this technique is often referred to as GABA+ . While few in number, previous studies have shown GABA+ levels increase with age during development. However, these studies are unable to specify whether it is specifically GABA that is increasing or, instead, if levels of MM increase. In this study, we use a GABA-editing technique specifically designed to suppress the MM signal (MM-supp GABA). We find no relationship between MM-supp GABA and age in healthy children aged 7–14 years. These findings suggest that the relationship between GABA+ and age is driven by changes in MM levels, not by changes in GABA levels. Moreover, these findings highlight the importance of accounting for MM levels in MRS quantification.

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