scholarly journals Identification of second malignancies on effusions and fine-needle aspirates using a panel of monoclonal antibodies

1997 ◽  
Vol 75 (4) ◽  
pp. 572-578
Author(s):  
M Mottolese ◽  
I Venturo ◽  
M Rinaldi ◽  
M Lopez ◽  
G Bigotti ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Second Malignancies ◽  
Fine Needle ◽  
Fine Needle Aspirates

scholarly journals Canine Lymphoma: Immunocytochemical Analysis of Fine-needle Aspiration Biopsy

1996 ◽  
Vol 33 (2) ◽  
pp. 204-212 ◽  
Author(s):  
M. Caniatti ◽  
P. Roccabianca ◽  
E. Scanziani ◽  
S. Paltrinieri ◽  
P. F. Moore
Keyword(s):  
Monoclonal Antibodies ◽  
Polyclonal Antibody ◽  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Surface Antigens ◽  
Needle Aspiration ◽  
Canine Lymphoma ◽  
Fine Needle ◽  
Immunocytochemical Analysis ◽  
Fine Needle Aspirates

Cytospin preparations of fine-needle aspirates from 21 dogs with peripheral lymphadenopathy (18 with lymphoma and three with lymph node hyperplasia) were studied by combining morphologic and immunocytochemical analysis. Fine-needle aspirates were taken from at least two enlarged lymph nodes, and the diagnosis was based on air-dried smears stained with May-Grünwald Giemsa. Fine-needle aspiration biopsy always provided an adequate quality and quantity of cells to perform morphologic and immunologic studies. Immunophenotyping was performed on cytospin preparations with a panel of eight monoclonal antibodies specific for canine cell surface antigens and one rabbit polyclonal antibody (A452) against human CD3, which cross-reacts with dog antigen. The immunocytochemical study resulted in the diagnosis of 14 B-cell lymphomas (CD21 +, CD3-) and three T-cell lymphomas (all CD3 +, two CD8+). One lymphoma lacked surface antigens specific for the B- or T-cell lineage and was classified as non-B-non-T lymphoma (CD21-, CD3-, CD4-, CD8-). The monoclonal antibodies CA12.10C12, CA4.1D3, and CA1D6 and the polyclonal antibody A452, used as a group, appeared to be the most useful reagents to suggest lymphoid origin and to discriminate between T- and B-cell phenotype. Cytospin preparations in combination with immunocytochemistry provided a practical, economical, and accurate method for the diagnosis and phenotyping of canine lymphoma.

LYMPHOID INFILTRATION IN TOXIC GOITRES STUDIED WITH FINE NEEDLE ASPIRATION BIOPSY

1972 ◽  
Vol 71 (3) ◽  
pp. 480-490 ◽  
Author(s):  
Göran Nilsson
Keyword(s):  
Fine Needle Aspiration ◽  
Fine Needle Aspiration Biopsy ◽  
Needle Aspiration ◽  
Lymphoid Cells ◽  
Aspiration Biopsy ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Needle Aspiration Biopsy ◽  
Lymphoid Infiltration ◽  
Long Acting

ABSTRACT Cytodiagnostic fine needle aspiration biopsy specimens from toxic goitres were studied for signs of lymphoid infiltration. Comparison with histological sections of specimens obtained by surgery showed that an excess of lymphoid cells in the aspirate smears corresponded to a large number of lymphoid foci in these sections. Excess of lymphoid cells in the fine needle aspirates was also positively correlated with the occurrence of circulating thyroid antibodies against thyroglobulin and/or cytoplasmic antigen, but not with the presence of the long-acting thyroid stimulating factor, LATS. It also varied with age in that it was most common in the youngest patients and in patients between 40–55 years, while lymphoid infiltration was seldom seen in patients over 55 years. A finding of practical clinical interest was that in toxic goitres with cytological signs of lymphoid infiltration hyperthyroidism had less tendency to recur after treatment with thiocarbamide drugs than in those without such signs.

The value of parathyroid hormone determination in ultrasound-guided fine-needle aspirates (FNA-PTH) for preoperative localization of parathyroid lesions.

2014 ◽  
Author(s):  
Magdalena Kochman ◽  
Waldemar Misiorowski ◽  
Lucyna Papierska ◽  
Elzbieta Stachlewska-Nasfeter ◽  
Witold Chudzinski ◽  
...  
Keyword(s):  
Parathyroid Hormone ◽  
Preoperative Localization ◽  
Ultrasound Guided ◽  
Fine Needle ◽  
Fine Needle Aspirates ◽  
Parathyroid Lesions
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