scholarly journals Endothelial cell differentiation into capillary-like structures in response to tumour cell conditioned medium: a modified chemotaxis chamber assay

1995 ◽  
Vol 71 (4) ◽  
pp. 770-775 ◽  
Author(s):  
T Garrido ◽  
HH Riese ◽  
M Aracil ◽  
A Pérez-Aranda
Keyword(s):  
Endothelial Cell ◽  
Cell Differentiation ◽  
Conditioned Medium ◽  
Tumour Cell ◽  
Endothelial Cell Differentiation ◽  
Cell Conditioned Medium

An integrated microfluidic culture device to regulate endothelial cell differentiation from embryonic stem cells

2011 ◽  
Vol 32 (22) ◽  
pp. 3133-3137 ◽  
Author(s):  
Jong Min Lee ◽  
Ji-eun Kim ◽  
Edward Kang ◽  
Sang-Hoon Lee ◽  
Bong Geun Chung
Keyword(s):  
Stem Cells ◽  
Endothelial Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Endothelial Cell Differentiation

Endothelial cell-conditioned medium downregulates smooth muscle contractile protein expression

1997 ◽  
Vol 272 (2) ◽  
pp. C582-C591 ◽  
Author(s):  
S. M. Vernon ◽  
M. J. Campos ◽  
T. Haystead ◽  
M. M. Thompson ◽  
P. E. DiCorleto ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Endothelial Cell ◽  
Growth Factor ◽  
Protein Expression ◽  
Conditioned Medium ◽  
Transforming Growth Factor Beta ◽  
Transforming Growth Factor ◽  
Contractile Protein ◽  
Alpha Actin ◽  
Cell Conditioned Medium

Smooth muscle cells (SMC) within atherosclerotic lesions proliferate and exhibit phenotypic modulation, but the contribution of vascular endothelium to this process is poorly understood. Our aim was to examine the effects of endothelial cell-conditioned medium (ECCM) on vascular SMC growth and differentiation. Rat aortic ECCM stimulated a ninefold increase in [3H]thymidine incorporation and downregulated smooth muscle-specific myosin heavy chain and alpha-actin synthesis in rat aortic SMC. These effects were not inhibited by antibodies to platelet-derived growth factor (PDGF)-BB or PDGF-AB or with a PDGF beta-receptor subunit. Treatment with PDGF-BB (at a concentration found in ECCM), PDGF-AA, basic fibroblast growth factor, endothelin-1, or transforming growth factor-beta did not reproduce these effects. The ECCM activities were sensitive to heat and trypsinization, were >30 kDa in molecular mass, and bound weakly to heparin-Sepharose. Our data indicate that cultured endothelial cells produce a factor(s) that downregulates contractile protein expression in SMC, which may contribute to SMC dedifferentiation and proliferation.

TGFβ1 inhibits lymphatic endothelial cell differentiation from mouse embryonic stem cells

2012 ◽  
Vol 227 (11) ◽  
pp. 3593-3602 ◽  
Author(s):  
Daniel Vittet ◽  
Galina Merdzhanova ◽  
Marie-Hélène Prandini ◽  
Jean-Jacques Feige ◽  
Sabine Bailly
Keyword(s):  
Stem Cells ◽  
Endothelial Cell ◽  
Cell Differentiation ◽  
Embryonic Stem Cells ◽  
Embryonic Stem ◽  
Lymphatic Endothelial Cell ◽  
Mouse Embryonic Stem Cells ◽  
Endothelial Cell Differentiation

Ly-6C is a monocyte/macrophage and endothelial cell differentiation antigen regulated by interferon-gamma

1988 ◽  
Vol 18 (11) ◽  
pp. 1819-1826 ◽  
Author(s):  
Mark A. Jutila ◽  
G. M. Kroese ◽  
Kathy L. Jutila ◽  
Alan M. Stall ◽  
Steve Fiering ◽  
...  
Keyword(s):  
Endothelial Cell ◽  
Cell Differentiation ◽  
Interferon Gamma ◽  
Differentiation Antigen ◽  
Endothelial Cell Differentiation

scholarly journals The role of Hath6, a newly identified shear-stress-responsive transcription factor, in endothelial cell differentiation and function

2014 ◽  
Vol 127 (7) ◽  
pp. 1428-1440 ◽  
Author(s):  
F. Fang ◽  
S. M. Wasserman ◽  
J. Torres-Vazquez ◽  
B. Weinstein ◽  
F. Cao ◽  
...  
Keyword(s):  
Shear Stress ◽  
Transcription Factor ◽  
Endothelial Cell ◽  
Cell Differentiation ◽  
Endothelial Cell Differentiation ◽  
And Function
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