scholarly journals The Inter-Regional Epidemiological Study of Childhood Cancer (IRESCC): case control study of children with bone and soft tissue sarcomas

1988 ◽  
Vol 58 (6) ◽  
pp. 838-842 ◽  
Author(s):  
AL Hartley ◽  
JM Birch ◽  
PA McKinney ◽  
MD Teare ◽  
V Blair ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Childhood Cancer ◽  
Epidemiological Study ◽  
Case Control Study ◽  
Soft Tissue Sarcomas ◽  
Case Control ◽  
Control Study

scholarly journals The inter-regional epidemiological study of childhood cancer (IRESCC): a case control study of aetiological factors in leukaemia and lymphoma.

1987 ◽  
Vol 62 (3) ◽  
pp. 279-287 ◽  
Author(s):  
P A McKinney ◽  
R A Cartwright ◽  
J M Saiu ◽  
J R Mann ◽  
C A Stiller ◽  
...  
Keyword(s):  
Childhood Cancer ◽  
Epidemiological Study ◽  
Case Control Study ◽  
Case Control ◽  
Control Study

scholarly journals Case–control study of paternal occupational exposures and childhood bone tumours and soft-tissue sarcomas in Great Britain, 1962–2010

2020 ◽  
Vol 122 (8) ◽  
pp. 1250-1259
Author(s):  
Gerald M. Kendall ◽  
Kathryn J. Bunch ◽  
Charles A. Stiller ◽  
Timothy J. Vincent ◽  
Michael F. G. Murphy
Keyword(s):  
Great Britain ◽  
Soft Tissue ◽  
Case Control Study ◽  
Soft Tissue Sarcomas ◽  
Occupational Exposures ◽  
Case Control ◽  
Bone Tumours ◽  
Control Study

The Inter-Regional, Epidemiological Study of Childhood Cancer (IRESCC): case-control study in children with germ cell tumours

1986 ◽  
Vol 7 (5) ◽  
pp. 717-722 ◽  
Author(s):  
H.E. Johnston ◽  
J.R. Mann ◽  
J. Williams ◽  
J.A.H. Waterhouse ◽  
J.M. Birch ◽  
...  
Keyword(s):  
Germ Cell ◽  
Childhood Cancer ◽  
Epidemiological Study ◽  
Case Control Study ◽  
Case Control ◽  
Germ Cell Tumours ◽  
Control Study

Tissue trauma and the subsequent risk of soft tissue sarcoma of the extremity: A population based case-control study in Sweden.

2017 ◽  
Vol 35 (15_suppl) ◽  
pp. e13088-e13088
Author(s):  
Hakan Lars Olsson ◽  
Philippe Wagner
Keyword(s):  
Soft Tissue ◽  
Case Control Study ◽  
Population Attributable Risk ◽  
Soft Tissue Sarcomas ◽  
Case Control ◽  
The Body ◽  
Accidental Injury ◽  
Physical Trauma ◽  
Tissue Trauma ◽  
Control Study

e13088 Background: Soft tissue sarcomas (STS) are a rare group of heterogeneous tumors that may occur in the extremities. Little is known of their etiologies and only a handful putative risk factors have been identified. Studies as well as case reports have connected soft tissue tumors to events of physical trauma. There is mounting evidence of inflammation as both an initiator and promotor of tumorigenesis, as well progression. Moreover, as the physiological response of tissue repair and regeneration is mediated through inflammation, it is not unlikely that physical injury may cause and/or contribute to tumor initiation, promotion and/or progression, not least when the subsequent inflammation becomes chronic. Methods: We conducted a matched case control study in a total population in the South of Sweden 1988-2009, collecting 249 cases to examine the risk of STS of the extremities (STSE) following exposure to physical trauma such as accidental injury and/or surgery. Results: Having been exposed to surgery or injury from accidents to any part of the body both increased the risk of STSE, OR 2.1 (1.5 – 3) and 1.5 (1.1 – 2.1), respectively. Adjusting for potential confounders yielded ORs of 2.4 (1.6 – 3.6) and 1.4 (1.00 – 2.00). Surgery related odds ratios (SOR) varied with STSE histological subtype, from 1.2 to 4.2. UPS/MFH, Leiomyosarcoma and Liposarcoma showed significantly elevated SORs that were significantly greater than for remaining subtypes (P = 0.029). The accident related odds ratio (AOR) varied from 0.8 to 3.5, being significantly elevated for Leiomyo- and Liposarcoma, and the AOR of the two combined was significantly greater than remaining subtypes (P = 0.045). Analyzing surgery or accidental injury to a given part of the body and the subsequent STSE risk in the same location showed the SOR to be 4.13 (1.87 – 9.15) and the AOR was 2.29 (1.21 – 4.32). Conclusions: The population attributable risk of having had surgery was 37% (20 – 53%) and accidental injury was 13% (2 – 24%). Combined, the PAR was 43% (25 – 57%), indicating that tissue trauma may be an important contributing factor in sarcomagenesis of the extremities.

Case Control Study of Soft Tissue Sarcomas in Relation to Dioxin Exposure in the Venice Province

Epidemiology ◽  
2006 ◽  
Vol 17 (Suppl) ◽  
pp. S486
Author(s):  
P Zambon ◽  
E Bovo ◽  
A Casula ◽  
M Gattolin ◽  
P Ricci ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Case Control Study ◽  
Soft Tissue Sarcomas ◽  
Case Control ◽  
Dioxin Exposure ◽  
Control Study

Risk Factors for Soft Tissue Sarcomas in Childhood: A Case-Control Study

1989 ◽  
Vol 75 (4) ◽  
pp. 396-400 ◽  
Author(s):  
Corrado Magnani ◽  
Guido Pastore ◽  
Lia Luzzatto ◽  
Modesto Carli ◽  
Paolo Lubrano ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Maternal Employment ◽  
Case Control Study ◽  
Soft Tissue Sarcomas ◽  
Case Control ◽  
Medical Doctor ◽  
Smoking Habits ◽  
Children's Diseases ◽  
Children’S Exposure ◽  
Control Study

A hospital-based case-control study on soft tissue sarcomas (STS) was conducted in 1983-84 in Torino and in Padova (Italy). Cases (36 children with rhabdomyosarcoma (RMS) and 16 non RMS-STS) were compared to 326 controls. Histories of parental smoking habits and occupations, parental and children's exposure to ionizing radiation, children's diseases and some other variables were collected through interviews to the relatives attending the child in the hospital. A non statistically significant association was observed with both maternal age above 30 at child's birth (STS: OR = 1.5, C.I. = 0.8-2.9; RMS: OR = 1.9, C.I. = 0.9-4.0) and « in utero » exposure to diagnostic radiation (STS: OR = 1.9, C.I. = 0.5-6.5, based on 4 cases). No association was found with children's previous diseases. Paternal and maternal smoking habits were similar for RMS and STS cases and controls. Some positive associations with either maternal or paternal occupational histories were identified. They are difficult to interpret in view of the large number of comparisons and small absolute figures. They included maternal employment as medical doctor and nurse, farmer, textile worker and machine tool operator. An association was also observed with paternal occupation as butcher, building worker or employment in the production of domestic appliances. One case and no controls reported a maternal aunt affected by breast cancer.

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