scholarly journals Successful treatment of colon cancer in rats with recombinant interferon-gamma

1987 ◽  
Vol 56 (6) ◽  
pp. 795-796 ◽  
Author(s):  
JNM Ijzermans ◽  
RL Marquet ◽  
E Bouwman ◽  
RWF de Bruin ◽  
PH van der Meide ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Interferon Gamma ◽  
Successful Treatment ◽  
Recombinant Interferon

Successful treatment of plaque stage mycosis fungoides with recombinant interferon-.GAMMA. (SUN 4800) alone.

1989 ◽  
Vol 51 (4) ◽  
pp. 784-788 ◽  
Author(s):  
Hideo ONODERA ◽  
Takashi HORIKOSHI ◽  
Shunsuke MIURA ◽  
Hiroaki EGUCHI ◽  
Kuniko KAWAMURA ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Interferon Gamma ◽  
Successful Treatment ◽  
Recombinant Interferon

Recognition of recombinant interferon-gamma from Felidae species by anti-cat antibodies

2021 ◽  
pp. 110327
Author(s):  
Jordan L. Mitchell ◽  
Anna Raper ◽  
Danièlle A. Gunn-Moore ◽  
Jayne C. Hope
Keyword(s):  
Interferon Gamma ◽  
Recombinant Interferon

scholarly journals Human recombinant interferon gamma enhances neonatal polymorphonuclear leukocyte activation and movement, and increases free intracellular calcium.

1991 ◽  
Vol 173 (3) ◽  
pp. 767-770 ◽  
Author(s):  
H R Hill ◽  
N H Augustine ◽  
H S Jaffe
Keyword(s):  
Intracellular Calcium ◽  
Interferon Gamma ◽  
Messenger Rna ◽  
Intrinsic Defect ◽  
Mononuclear Leukocytes ◽  
Developmental Defect ◽  
Phagocytic Cells ◽  
Ifn Gamma ◽  
Recombinant Interferon ◽  
Free Intracellular Calcium

In previous studies, we have reported that after chemotactic factor stimulation, PMNs from neonates fail to undergo certain critical activation steps. Furthermore, the concentration of free intracellular calcium reached is significantly below that of PMNs from adults. Interferon-gamma (IFN-gamma) is a lymphokine that has been shown to activate phagocytic cells, and IFN-gamma messenger RNA production by neonatal mononuclear leukocytes has been reported to be depressed. In the present studies, we found that recombinant human IFN-gamma markedly enhanced the chemotactic responses of PMNs from neonates to levels that were not different from that of PMNs from adults. Furthermore, preincubation of the neonatal cells with this recombinant human lymphokine also corrected the abnormality in intracellular calcium metabolism. These results suggest that this developmental defect in phagocytic cell movement may be the result of an intrinsic defect in IFN-gamma production resulting in deficiency of this critical phagocyte-activating lymphokine.

Histiocytosis X: Successful Treatment with Recombinant Interferon-αA

1990 ◽  
Vol 32 (2) ◽  
pp. 151-154 ◽  
Author(s):  
Yuichi Sato ◽  
Yasuhiko Ikeda ◽  
Etsuro Ito ◽  
Takakazu Miyano ◽  
Kyoichi Kawauchi ◽  
...  
Keyword(s):  
Successful Treatment ◽  
Histiocytosis X ◽  
Recombinant Interferon
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