scholarly journals A comparison of the endocrine effects of low dose aminoglutethimide with and without hydrocortisone in postmenopausal breast cancer patients

1985 ◽  
Vol 52 (4) ◽  
pp. 525-529 ◽  
Author(s):  
M Dowsett ◽  
A L Harris ◽  
R Stuart-Harris ◽  
M Hill ◽  
B M Cantwell ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Low Dose ◽  
Postmenopausal Breast Cancer ◽  
Breast Cancer Patients ◽  
Endocrine Effects

265 Endocrine effects of low dose aminoglutethimide without hydrocortisone in breast cancer patients

1983 ◽  
Vol 19 ◽  
pp. 88
Author(s):  
R. Stuart-Harris ◽  
M. Dowsett ◽  
A. D'Souza ◽  
S.L. Jeffcoate ◽  
I.E. Smith
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Low Dose ◽  
Breast Cancer Patients ◽  
Endocrine Effects

Endocrine Effects of Tamoxifen in Postmenopausal Breast Cancer Patients

1984 ◽  
Vol 70 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Francesco Boccardo ◽  
Domenico Guarneri ◽  
Alessandra Rubagotti ◽  
Gian Luigi Casertelli ◽  
Giorgio Bentivoglio ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Postmenopausal Breast Cancer ◽  
Sex Hormone Binding Globulin ◽  
Tamoxifen Treatment ◽  
Prolonged Treatment ◽  
Breast Cancer Patients ◽  
Vaginal Smears ◽  
Endocrine Effects ◽  
Estradiol 17Β

The effects of tamoxifen on plasma concentration of gonadotropins, prolactin (PRL), estrone (E1), estradiol-17β (E2), and sex hormone-binding globulin (SHBG) were studied in 40 postmenopausal breast cancer patients. In addition, the changes induced by the drug on endometrium and vaginal epithelium were investigated. After 6–8 weeks of tamoxifen treatment, a significant decrease in FSH, LH and PRL basal levels was observed, whereas the concentrations of E1 and E2 were not significantly affected. A significant increase in SHBG levels was induced by prolonged treatment with the drug. In addition, tamoxifen caused a partial estrogenization of vaginal smears, and a weak stimulatory effect on endometrium was also apparent. These findings indicate that tamoxifen produced agonistic effects on some targets and antagonistic effects on the others.

Different Coexisting Gynecological and Endometrial Pathologies in Postmenopausal Breast Cancer Patients Treated with Tamoxifen

1998 ◽  
Vol 46 (2) ◽  
pp. 123-129 ◽  
Author(s):  
Ilan Cohen ◽  
Yoram Beyth ◽  
Joelle Bernheim ◽  
Jeremiah Shapira ◽  
Mario Cordoba ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Postmenopausal Breast Cancer ◽  
Breast Cancer Patients
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