scholarly journals Prognostic value of preoperative serum CEA level compared to clinical staging. I. Colorectal carcinoma

1981 ◽  
Vol 44 (5) ◽  
pp. 652-662 ◽  
Author(s):  
H J Staab ◽  
F A Anderer ◽  
T Brümmendorf ◽  
E Stumpf ◽  
R Fischer
1982 ◽  
Vol 45 (5) ◽  
pp. 718-727 ◽  
Author(s):  
H J Staab ◽  
F A Anderer ◽  
T Brümmendorf ◽  
A Hornung ◽  
R Fischer

1996 ◽  
Vol 11 (1) ◽  
pp. 6-11 ◽  
Author(s):  
N. Pavlidis ◽  
C. Nicolaides ◽  
E. Bairaktari ◽  
J. Kalef-Ezra ◽  
A. Athanassiadis ◽  
...  

The levels of soluble interleukin-2 receptors (sIL-2R) were measured in the serum of 52 patients with advanced colorectal carcinoma and compared to CEA and CA 19-9 levels. Twenty-five normal, age and sex-matched individuals served as controls. Seventy-five per cent of the patients had increased mean serum levels of sIL-2R (1539 ± 155 U/ml), while normal controls had mean levels of 555 ± 31 U/ml (p < 0.001). The relationship with hepatic or lymph nodal metastases showed no statistically significant difference (p=0.34 and p=0.47, respectively). Serum sIL-2R levels showed a linear correlation with CEA (p < 0.05). Patients with lower pretreatment sIL-2R levels (less than 1.200 U/ml) had a longer survival than patients with higher initial levels (more than 1.200 U/ml) (p=0.0049). In conclusion, the present work shows that the serum levels of sIL-2R: a) are elevated in patients with advanced colorectal cancer, b) have no relationship with the type of metastases, c) correlate with serum CEA and d) have a prognostic value for survival.


1983 ◽  
Vol 69 (1) ◽  
pp. 23-30 ◽  
Author(s):  
Józef Kula ◽  
Antonina Harlozinska ◽  
Roman Richter ◽  
Zygmunt Albert ◽  
Józef Sward ◽  
...  

The presence of carcinoembryonic antigen (CEA)-dependent fluorescence was observed in almost 89% of female genital tract cancers irrespective of their histologic type. Anti-CEA serum was free of antibody to normal cross-reacting antigen. The high percentage of positive fluorescence tests did not correlate with the preoperative serum CEA levels. Double immunodiffusion tests showed different content of CEA and normal cross-reacting antigen in individual specimens of genital tract cancers.


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