scholarly journals Benzbromarone, an old uricosuric drug, inhibits human fatty acid binding protein 4 in vitro and lowers the blood glucose level in db/db mice

2013 ◽  
Vol 34 (11) ◽  
pp. 1397-1402 ◽  
Author(s):  
Hai-yan Cai ◽  
Ting Wang ◽  
Jian-chun Zhao ◽  
Peng Sun ◽  
Gui-rui Yan ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Glucose Level ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Giardiasis Alters Intestinal Fatty Acid Binding Protein (I-FABP) and Plasma Cytokines Levels in Children in Brazil

Pathogens ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 7
Author(s):  
Tiara Cascais-Figueiredo ◽  
Phelipe Austriaco-Teixeira ◽  
Maria Fantinatti ◽  
Maria Luciana Silva-Freitas ◽  
Joanna Reis Santos-Oliveira ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Low Income ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Developed Countries ◽  
Mucosal Barrier ◽  
Fatty Acid Binding ◽  
Epithelial Damage ◽  
Acid Binding Protein

Giardiasis is an intestinal infection caused by ingestion of water or food contaminated with cysts of Giardia lamblia. Susceptibility is higher in children and overall prevalence can reach up to 90% in low-income areas, although outbreaks are also reported in developed countries. Both parasite and immune-mediated epithelial damage has been observed in vitro and in animal models. However, whether enterocytes are directly damaged during infection is not entirely known. Our goal was to identify whether plasma levels of intestinal fatty acid binding protein (I-FABP), a marker of enterocyte damage, are related to the immune response in giardiasis. Blood plasma was collected from 31 children (19 Giardia-positive) from a public day care in Rio de Janeiro, Brazil. The levels of I-FABP were increased in Giardia-infected children compared to children without detectable infection. There was no difference in I-FABP levels in giardiasis caused by different genetic assemblages of Giardia. Levels of IL-8 were decreased, while there was a trend to elevated IL-17 in the Giardia-positive children. A positive correlation was observed between I-FABP and IL-17 levels as well as TNF, suggesting that epithelial damage can be related to cytokine production during giardiasis. These results help elucidate the relationship between the disruption of the intestinal mucosal barrier and immune responses to G. lamblia in children.

804 FATTY ACID BINDING PROTEIN 4 INHIBITOR INHIBITS PANCREATIC CANCER GROWTH IN VITRO AND IN VIVO.

2021 ◽  
Vol 160 (6) ◽  
pp. S-166
Author(s):  
Shuhei Shinoda ◽  
Keith Wirth ◽  
Sayeed Ikramuddin ◽  
David A. Bernlohr ◽  
Masato Yamamoto
Keyword(s):  
Pancreatic Cancer ◽  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Cancer Growth ◽  
Fatty Acid Binding ◽  
Acid Binding Protein

scholarly journals Fatty Acid Binding Protein 3 And Transzonal Projections Are Involved In Lipid Accumulation During In Vitro Maturation Of Bovine Oocytes

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Maite del Collado ◽  
Juliano Coelho da Silveira ◽  
Juliano Rodrigues Sangalli ◽  
Gabriella Mamede Andrade ◽  
Letícia Rabello da Silva Sousa ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Lipid Accumulation ◽  
In Vitro Maturation ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Fatty Acid Binding ◽  
Acid Binding Protein ◽  
Bovine Oocytes

Calcium-dependent release of adipocyte fatty acid binding protein from human adipocytes

2014 ◽  
Vol 122 (03) ◽  
Author(s):  
I Schlottmann ◽  
M Ehrhart-Bornstein ◽  
M Wabitsch ◽  
SR Bornstein ◽  
V Lamounier-Zepter
Keyword(s):  
Fatty Acid ◽  
Fatty Acid Binding Protein ◽  
Binding Protein ◽  
Human Adipocytes ◽  
Fatty Acid Binding ◽  
Calcium Dependent ◽  
Acid Binding Protein
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