scholarly journals No association between LRP5 gene polymorphisms and bone and obesity phenotypes in Chinese male-offspring nuclear families

2010 ◽  
Vol 31 (11) ◽  
pp. 1464-1469 ◽  
Author(s):  
Jin-bo Yu ◽  
Yao-hua Ke ◽  
Jin-wei He ◽  
Hao Zhang ◽  
Wei-wei Hu ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Male Offspring ◽  
Nuclear Families ◽  
Chinese Male

Contribution of the Myostatin gene polymorphisms to normal variation in lean mass and fat mass in Chinese male offspring nuclear families

Bone ◽  
2010 ◽  
Vol 47 ◽  
pp. S364
Author(s):  
Hua Yue ◽  
Jin-Wei He ◽  
Zhen-Lin Zhang ◽  
Hao Zhang ◽  
Chun Wang ◽  
...  
Keyword(s):  
Fat Mass ◽  
Lean Mass ◽  
Gene Polymorphisms ◽  
Male Offspring ◽  
Normal Variation ◽  
Myostatin Gene ◽  
Nuclear Families ◽  
Chinese Male

scholarly journals The rs1634330 Polymorphisms in the SOST Gene Are Associated with Body Composition in Chinese Nuclear Families with Male Offspring

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Luyue Qi ◽  
Lianyong Liu ◽  
Li Li ◽  
Weiwei Hu ◽  
Wenzhen Fu ◽  
...  
Keyword(s):  
Body Composition ◽  
The Body ◽  
Male Offspring ◽  
Nucleotide Polymorphisms ◽  
Quantitative Transmission Disequilibrium Test ◽  
Single Nucleotide ◽  
Nuclear Families ◽  
X Ray ◽  
Sost Gene ◽  
Chinese Male

Objective. The purpose of this study was to explore the effect of the SOST gene polymorphisms on body composition in Chinese nuclear families with male offspring. Methods. 1,016 individuals were recruited from 335 Chinese nuclear families with male offspring. The nuclear families consist of at least one male offspring aged 18 to 44. We genotyped the 10 tagged single-nucleotide polymorphisms (SNPs) in SOST gene (rs7220711, rs865429, rs851057, rs1708635, rs2023794, rs1234612, rs74252774, rs1634330, rs851058, and rs1513670) in all the above people. We used dual-energy X-ray absorptiometry to measure the composition of the human body. The quantitative transmission disequilibrium test (QTDT) was used to analyze the associations of the SNPs with the body composition. Results. QTDT analysis showed that rs1634330 was significantly associated with trunk LM P < 0.05 . However, haplotypes were not found to be significantly associated with the body composition in the within-family association. The 1000 permutations were consistent with these within-family association results. Conclusions. Our results showed that the genetic variation in the SOST gene may contribute to variations in the body composition of Chinese male offspring.

scholarly journals Contribution of Myostatin gene polymorphisms to normal variation in lean mass, fat mass and peak BMD in Chinese male offspring

2012 ◽  
Vol 33 (5) ◽  
pp. 660-667 ◽  
Author(s):  
Hua Yue ◽  
Jin-wei He ◽  
Hao Zhang ◽  
Chun Wang ◽  
Wei-wei Hu ◽  
...  
Keyword(s):  
Fat Mass ◽  
Lean Mass ◽  
Gene Polymorphisms ◽  
Male Offspring ◽  
Normal Variation ◽  
Myostatin Gene ◽  
Chinese Male ◽  
Peak Bmd

scholarly journals Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring

2012 ◽  
Vol 33 (2) ◽  
pp. 201-207 ◽  
Author(s):  
Yao-hua Ke ◽  
Wen-jin Xiao ◽  
Jin-wei He ◽  
Hao Zhang ◽  
Jin-bo Yu ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Male Offspring ◽  
Nuclear Families

scholarly journals Association between VDR and ESR1 gene polymorphisms with bone and obesity phenotypes in Chinese male nuclear families

2009 ◽  
Vol 30 (12) ◽  
pp. 1634-1642 ◽  
Author(s):  
Jie-mei Gu ◽  
Wen-jin Xiao ◽  
Jin-wei He ◽  
Hao Zhang ◽  
Wei-wei Hu ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Nuclear Families ◽  
Esr1 Gene ◽  
Chinese Male

scholarly journals Association analyses of CYP19 gene polymorphisms with height variation in a large sample of Caucasian nuclear families

2006 ◽  
Vol 120 (1) ◽  
pp. 119-125 ◽  
Author(s):  
Tie-Lin Yang ◽  
Dong-Hai Xiong ◽  
Yan Guo ◽  
Robert R. Recker ◽  
Hong-Wen Deng
Keyword(s):  
Gene Polymorphisms ◽  
Height Variation ◽  
Association Analyses ◽  
Nuclear Families ◽  
Large Sample ◽  
Cyp19 Gene
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