scholarly journals Molecular Trafficking of Angiotensin Receptors

2012 ◽  
Vol 25 (1) ◽  
pp. 23-23
Author(s):  
T. Goodfriend
Keyword(s):  
Angiotensin Receptors ◽  
Molecular Trafficking

The Renin Angiotensin System and Bipolar Disorder: A Systematic Review

2020 ◽  
Vol 27 (6) ◽  
pp. 520-528 ◽  
Author(s):  
Izabela Guimarães Barbosa ◽  
Giulia Campos Ferreira ◽  
Diomildo Ferreira Andrade Júnior ◽  
Cássio Rocha Januário ◽  
André Rolim Belisário ◽  
...  
Keyword(s):  
Systematic Review ◽  
Bipolar Disorder ◽  
Cardiovascular Diseases ◽  
Renin Angiotensin System ◽  
Plasma Renin ◽  
Angiotensin Receptors ◽  
Angiotensin System ◽  
Renin Angiotensin ◽  
Search Terms

Bipolar Disorder (BD) is a chronic a multifactorial psychiatric illness that affects mood, cognition, and functioning. BD is associated with several psychiatric conditions as well clinical comorbidities, particularly cardiovascular diseases. The neurobiology of BD is complex and multifactorial and several systems have been implicated. Considering that the Renin Angiotensin System (RAS) plays an important role in cardiovascular diseases and that recently evidence has suggested its role in psychiatric disorders, the aim of the present study is to summarize and to discuss recent findings related to the modulation of RAS components in BD. A systematic search of the literature using the electronic databases MEDLINE and LILACS was conducted through March 2019. The search terms were: “Bipolar Disorder”; “Renin Angiotensin System”; “Angiotensin 2”; “Angiotensin receptors”; “Angiotensin 1-7”; “ACE”; “ACE2”; “Mas Receptor”. We included original studies assessing RAS in BD patients. Two hundred twenty-two citations were initially retrieved. Eleven studies were included in our systematic review. In the majority of studies (6 of 8), the ACE insertion/deletion (I/D) polymorphism did not differ between BD patients and controls. BD patients presented higher plasma renin activity in comparison with controls. The studies evaluating the RAS molecules in BD are very scarce and heterogeneous. The literature suggests a potential role of RAS in BD. Further studies are necessary to investigate this relationship.

Angiotensin Receptors in Cardiac and Renal Hypertrophy in Rats

1997 ◽  
Vol 29 (11) ◽  
pp. 2925-2929 ◽  
Author(s):  
Lindsay Brown ◽  
Margaret Passmore ◽  
Brett Duce ◽  
Conrad Sernia
Keyword(s):  
Angiotensin Receptors ◽  
Renal Hypertrophy

Angiotensin Receptors and Their Antagonists

1996 ◽  
Vol 334 (25) ◽  
pp. 1649-1655 ◽  
Author(s):  
Theodore L. Goodfriend ◽  
Mary E. Elliott ◽  
Kevin J. Catt
Keyword(s):  
Angiotensin Receptors
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