scholarly journals Association of ACE2 Genetic Variants With Blood Pressure, Left Ventricular Mass, and Cardiac Function in Caucasians With Type 2 Diabetes

2012 ◽  
Vol 25 (2) ◽  
pp. 216-222 ◽  
Author(s):  
S. K. Patel ◽  
B. Wai ◽  
M. Ord ◽  
R. J. MacIsaac ◽  
S. Grant ◽  
...  
2010 ◽  
Vol 37 (10) ◽  
pp. 875-880 ◽  
Author(s):  
Edward Franek ◽  
Magdalena Napora ◽  
Anna Blach ◽  
Tadeusz Budlewski ◽  
Dariusz Gozdowski ◽  
...  

2011 ◽  
Vol 29 (10) ◽  
pp. 1994-2003 ◽  
Author(s):  
Giovanni Cioffi ◽  
Pompilio Faggiano ◽  
Donata Lucci ◽  
Andrea Di Lenarda ◽  
Gian Francesco Mureddu ◽  
...  

Diabetes Care ◽  
2005 ◽  
Vol 28 (4) ◽  
pp. 937-939 ◽  
Author(s):  
J. E. Sharman ◽  
Z. Y. Fang ◽  
B. Haluska ◽  
M. Stowasser ◽  
J. B. Prins ◽  
...  

2006 ◽  
Vol 1 (6) ◽  
pp. 1187-1190 ◽  
Author(s):  
Niloofar Nobakhthaghighi ◽  
Mohammed Kamgar ◽  
Mir R. Bekheirnia ◽  
Kim McFann ◽  
Raymond Estacio ◽  
...  

2009 ◽  
Vol 116 (7) ◽  
pp. 599-606 ◽  
Author(s):  
Dominica Zentner ◽  
Moira du Plessis ◽  
Shaun Brennecke ◽  
James Wong ◽  
Leeanne Grigg ◽  
...  

The aim of the present study was to undertake a longitudinal study of systolic and diastolic cardiac function during normal pregnancy. At a median of 16 weeks of gestation, 100 primiparous women underwent echocardiography, including tissue Doppler imaging, determining left ventricular mass, cardiac output, systolic and diastolic velocities, and wall stress. A total of 32 were assessed again at a median of 37 weeks of gestation. Non-pregnant control estimates (n=9) were obtained by averaging four separate measures over two menstrual cycles. Initially, the pregnant women had significantly higher pulse rates than controls, associated with greater ventricular wall stress (two-tailed P value=0.015), and systolic (two-tailed P value=0.005) and diastolic (two-tailed P value=0.018) lateral wall myocardial velocities, but no differences in systolic blood pressure, left ventricular mass or cardiac output. By 37 weeks of gestation, increased blood pressure (two-tailed P value <0.001) and left ventricular mass (two-tailed P value=0.002) were associated with a significant increase in ventricular wall stress (two-tailed P value <0.001), and reductions in septal systolic (two-tailed P value=0.004) and septal and lateral early diastolic (two-tailed P value <0.001) myocardial velocities. The diastolic velocities at 37 weeks correlated inversely with maternal weight and age. In conclusion, by term pregnancy, an increase in ventricular wall stress is accompanied by a deterioration in cardiac function.


Heart ◽  
2013 ◽  
Vol 99 (suppl 2) ◽  
pp. A93.1-A93
Author(s):  
B R S Szwejkowski ◽  
S G Gandy ◽  
S R Rekhraj ◽  
G H Houston ◽  
C C L Lang ◽  
...  

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