scholarly journals Insulin resistance predicts incident hypertension in lean persons and Genetic characteristics modify the blood pressure effect of exercise

2011 ◽  
Vol 24 (9) ◽  
pp. 959-959
Keyword(s):  
Insulin Resistance ◽  
Blood Pressure ◽  
Pressure Effect ◽  
Genetic Characteristics ◽  
Incident Hypertension ◽  
Blood Pressure Effect

Effect of a Competitive Angiotensin Antagonist on the Renal Haemodynamic Changes Induced by Inhibition of Prostaglandin Synthesis in Rats

1974 ◽  
Vol 48 (s2) ◽  
pp. 299s-302s ◽  
Author(s):  
A. Mimran ◽  
D. Casellas ◽  
M. Dupont ◽  
P. Barjon
Keyword(s):  
Blood Pressure ◽  
Pressure Effect ◽  
Renin Angiotensin System ◽  
Prostaglandin Synthesis ◽  
Sodium Balance ◽  
Angiotensin System ◽  
Blood Pressure Effect ◽  
Haemodynamic Changes ◽  
Inhibition Of Prostaglandin Synthesis ◽  
Angiotensin Receptor Blockade

1. Inhibition of prostaglandin synthesis by indomethacin induced an increase in blood pressure which did not occur when rats were bilaterally nephrectomized. 2. The blood pressure effect was related to the state of sodium balance and thus to the activity of the renin-angiotensin system. 3. Indomethacin induced a decrease in renal blood flow. 4. Angiotensin receptor blockade with Sar1-Ala8-angiotensin II blunted the blood pressure effect and prevented the renal haemodynamic changes induced by indomethacin.

Sympathetic and angiotensin-dependent hypertension during cage-switch stress in mice

2004 ◽  
Vol 287 (6) ◽  
pp. R1394-R1398 ◽  
Author(s):  
Dexter L. Lee ◽  
R. Clinton Webb ◽  
Michael W. Brands
Keyword(s):  
Blood Pressure ◽  
Drinking Water ◽  
Psychosocial Stress ◽  
Pressure Effect ◽  
Initial Increase ◽  
Pressure Curve ◽  
Similar Response ◽  
Renin Angiotensin ◽  
Blood Pressure Effect ◽  
Novel Model

The goal of this study was to determine the dependence of the acute hypertensive response to a novel model of acute psychosocial stress on the sympathetic and renin-angiotensin systems. Baseline mean arterial pressure (MAP), heart rate (HR), and locomotor activity were measured with telemetry in mice for a 1-h period and averaged 98 ± 1 mmHg, 505 ± 3 beats/min, and 5 ± 1 counts, respectively. Stress was induced by placing a mouse into a cage previously occupied by a different male mouse, and this increased MAP, HR, and activity in the control group by 40 ± 2 mmHg, 204 ± 25 beats/min, and 68 ± 6 counts, respectively. Each variable gradually returned to baseline levels by 90 min after beginning cage switch. Pretreatment with terazosin (10 mg/kg ip) significantly reduced the initial increase in MAP to 12 ± 6 mmHg, whereas MAP for the last 45 min was superimposable on control values. Atenolol (10 mg/ml drinking water) had no effect to blunt the initial increase in MAP but had a growing effect from 10 min onward, decreasing MAP all the way to baseline by 60 min after starting cage switch. Captopril (2 mg/ml drinking water) treatment caused a very similar response. All three treatments significantly decreased the area under the blood pressure curve, and the blood pressure effect could not be attributed uniformly to effects on HR or activity. These data suggest that our novel model of psychosocial stress causes an initial α1-receptor-dependent increase in MAP. The later phase of the pressor response is blocked similarly by a β1-receptor antagonist and an ACE inhibitor, independent of HR, suggesting that the β1-dependent blood pressure effect is due, in large part, to the renin-angiotensin system.

Placebo-Controlled Biofeedback Blood Pressure Effect in Hypertensive Humans

Hypertension ◽  
1997 ◽  
Vol 29 (6) ◽  
pp. 1225-1231 ◽  
Author(s):  
Stephen N. Hunyor ◽  
Robyn J. Henderson ◽  
Saroj K. L. Lal ◽  
Norman L. Carter ◽  
Henry Kobler ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Pressure Effect ◽  
Blood Pressure Effect

Diastolic blood pressure effect of traffic-related air pollution: a trial of vehicle filtration

2018 ◽  
Author(s):  
Michael Young ◽  
Karen Jansen ◽  
Tim Gould ◽  
Coralynn Sack ◽  
Laura Hooper ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Air Pollution ◽  
Diastolic Blood Pressure ◽  
Pressure Effect ◽  
Blood Pressure Effect
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