scholarly journals Surgical Rates for Crohn’s Disease are Decreasing: A Population-Based Time Trend Analysis and Validation Study

2017 ◽  
Vol 112 (12) ◽  
pp. 1840-1848 ◽  
Author(s):  
Christopher Ma ◽  
Gordon W Moran ◽  
Eric I Benchimol ◽  
Laura E Targownik ◽  
Steven J Heitman ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Validation Study ◽  
Time Trend ◽  
Population Based

Incidence Rates for Surgery in Crohn’s Disease Have Decreased: A Population-based Time-trend Analysis

2020 ◽  
Vol 26 (12) ◽  
pp. 1909-1916 ◽  
Author(s):  
Alexandra E Dittrich ◽  
Reed Taylor Sutton ◽  
Kate Haynes ◽  
Haili Wang ◽  
Richard N Fedorak ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Time Trend ◽  
Population Level ◽  
Population Based ◽  
Incidence Rates ◽  
Annual Percent Change ◽  
Related Data ◽  
Smoking Trends

Abstract Background Many Crohn’s disease (CD) patients will undergo surgery over the course of their life. It is thought that with the introduction of disease-modifying agents like anti-TNF therapy, there would be a population-level decrease in the need for surgery. This time-trend study aimed to assess the changes in surgical rates following the induction of anti-TNF therapy. Methods Adult CD patients who underwent abdominal surgery (identified by administrative coding) between January of 1996 and December of 2013 at 1 of the 4 Edmonton-area hospitals were included. Patient charts were manually reviewed to confirm diagnosis and gather demographic and disease-related data. Population-adjusted annual incidence rates for IBD surgery were calculated by dividing the number of surgeries by estimates for total population of CD patients in Edmonton. Time-trend analysis was conducted to identify change points, calculate annual percent change (APC), and associated 95% confidence intervals (CIs). Results A total of 1410 patients with Crohn’s disease underwent surgery for their disease. The surgical rate decreased by 8.4% each year (95% CI, −9.6% to −7.3%). There was a 36.2% increase in the use of anti-TNF therapy per year (95% CI, 31.3% to 41.5%). Changes in modifiable risk factors for surgery were also seen, including the proportion of active smokers decreasing by 2.2% per year (95% CI, −3.7% to −0.6%). Conclusions Although anti-TNF therapy seems to play a role, the decrease in surgical trends is likely multifactorial, owing to a decline in smoking trends, earlier diagnosis, earlier treatment, improved patient education, and changes in clinical practice.

76 Surgical Resection Rates for Crohn's Disease Are Decreasing: A Population-Based Time Trend Analysis

2016 ◽  
Vol 150 (4) ◽  
pp. S20
Author(s):  
Christopher Ma ◽  
Remo Panaccione ◽  
Gordon W. Moran ◽  
Eric Benchimol ◽  
Steven Heitman ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Surgical Resection ◽  
Time Trend ◽  
Population Based

scholarly journals Reduction in surgical stoma rates in Crohn's disease: a population‐based time trend analysis

2019 ◽  
Vol 21 (11) ◽  
pp. 1279-1287 ◽  
Author(s):  
C. Ma ◽  
A. Almutairdi ◽  
D. Tanyingoh ◽  
C. H. Seow ◽  
K. L. Novak ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Time Trend ◽  
Population Based

scholarly journals DOP039 Exploring stoma rates in Crohn’s disease in the biologic era: a population-based time trend analysis

2018 ◽  
Vol 12 (supplement_1) ◽  
pp. S057-S058
Author(s):  
C Ma ◽  
P G Kotze ◽  
A Almutairdi ◽  
D Tanyngoh ◽  
C Seow ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Time Trend ◽  
Population Based

474 - Exploring Stoma Rates in Crohn's Disease in the Biologic Era: A Population-Based Time Trend Analysis

2018 ◽  
Vol 154 (6) ◽  
pp. S-111-S-112
Author(s):  
Abdulelah A. Almutairdi ◽  
Christopher Ma ◽  
Paulo G. Kotze ◽  
Divine Tanyingoh ◽  
Cynthia H. Seow ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Trend Analysis ◽  
Time Trend ◽  
Population Based

Corrigendum: Surgical Rates for Crohnʼs Disease Are Decreasing: A Population-Based Time Trend Analysis and Validation Study

2018 ◽  
Vol 113 (2) ◽  
pp. 310 ◽  
Author(s):  
Christopher Ma ◽  
Gordon W Moran ◽  
Eric I Benchimol ◽  
Laura E Targownik ◽  
Steven J Heitman ◽  
...  
Keyword(s):  
Trend Analysis ◽  
Validation Study ◽  
Time Trend ◽  
Population Based

Tu1306 Surgical Rates Have Decreased for Emergent Crohn's Disease Resections While Increasing for Elective Resections: A Population-Based Time Trend Study

2012 ◽  
Vol 142 (5) ◽  
pp. S-798 ◽  
Author(s):  
Gilaad G. Kaplan ◽  
Gordon W. Moran ◽  
Alexandra Frolkis ◽  
Kevin P. Rioux ◽  
Subrata Ghosh ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Time Trend ◽  
Population Based ◽  
Trend Study

Risk of fracture in Crohn's disease: A population-based study

2001 ◽  
Vol 120 (5) ◽  
pp. A628-A628
Author(s):  
E LOFTUSJR ◽  
C CROWSON ◽  
W SANDBORN ◽  
W TREAMINE ◽  
W OFALLON ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Population Based ◽  
Population Based Study ◽  
Risk Of Fracture
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