Lumen-Apposing Metal Stents for the Treatment of Refractory Benign Esophageal Strictures

2017 ◽  
Vol 112 (3) ◽  
pp. 516-517 ◽  
Author(s):  
Douglas G Adler
2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Xing Wang ◽  
Haifeng Liu ◽  
Zhihong Hu ◽  
Rufang Zhang ◽  
Zhujun Gu ◽  
...  

AbstractTo share our institutional experience of placing individually designed fully covered self-expandable metal stents (FCSEMSs) for the treatment of refractory benign esophageal strictures (RBESs) in pediatric patients. A 10-year retrospective study between May 2009 and July 2020 that includes 14 children with RBESs who were treated with individually designed FCSEMSs. Patients were followed-up regularly after stent placement to observe the improvement of vomiting and dysphagia, changes in stenosis diameter and complications. A total of 20 stents were successfully placed in 14 patients. During a follow-up period ranging from 5 to 83 months, except for one 4-year-old child who could not endure chest pain, the remaining 13 patients all benefited from stenting. Their Ogilvie & Atkinson scores improved from grade III–IV to grade 0-I, and the diameters of the stenosis’ were enlarged from 2–5 mm to 9–14 mm. Two patients developed restenosis and granulation tissue hyperplasia was found in 2 patients and stent migration and malapposition in 2 patients with esophageal perforations that required further endoscopic intervention. The use of FCSEMS for RBES is safe and effective in selected pediatric patients. Rationally designed stents and timely management of postoperative complications are critical to ensure the success of this new method.


2019 ◽  
Vol 7 (13) ◽  
pp. 1623-1633 ◽  
Author(s):  
Qing Lu ◽  
Tian-Tian Lei ◽  
Yi-Lan Wang ◽  
Hai-Lin Yan ◽  
Bo Lin ◽  
...  

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 14-14
Author(s):  
Qing Lu ◽  
Tiantian Lei ◽  
Hailin Yan ◽  
Jinlin Yang ◽  
Hongsheng Ma

Abstract Background The outcomes of patients with refractory benign esophageal strictures (RBES) was unclear and lacking in relative researches on the clinical efficacy of dilation compared with stent placement. Our objective was to explore the role of endoscopic dilation and stents in the management of RBES. Methods This study including patients with RBES (recurrence of dysphagia despite endoscopic therapy more than 3 sessions) by dilation and stents between January 2009 and December 2017. Endoscopic therapy success was defined as: before the end of the follow-up, no need for endoscopic interventions for at least 6 months. The primary outcome was to assess clinical effectiveness and adverse events. Secondary outcome was to identify factors that predicted the dysphagia-free period (the time interval of two subsequent endoscopic interventions). Multivariate analysis was used to estimate the risk factors influencing the treatment success. To explore the trend of dysphagia-free period along with times used hierarchical linear models. Results 75 patients (54 male; median age, 59 years) with RBES, 39 (52%), 20 (26.7%), 3 (4%), 10(13.3%), and 3(4%) were post-surgical, post-ESD, achalasia of cardia, caustic and mixed etiology, respectively. The median times of endoscopic therapy was 5 times (range 3, 21). Self-expandable metal stents (SEMSs) were placed in 20 patients (26.7%), and the success rate of patients treated with dilation (70.9%, 39/55) was higher than with stents (35%, 7/20). Fifteen patients died during follow-up. Nineteen patients had adverse events after endoscopic therapy. In total, the mean dysphagia-free period was 3.4 months (95% CI, 2.5–4.3). The dysphagia-free period of patients treated with dilation was 3.7months (95% CI, 2.7–5), and with stents was 2.3 months (95% CI, 1.5–3). The dysphagia-free period has linear growth trend with times, increased by 12 days per endoscopic therapy. Conclusion The dysphagia-free period increased by 12 days per endoscopic therapy, so the endoscopic dilation and stents tended to be effective in patients with RBES. Before the end of follow-up, nearly half of patients required continuing endoscopic dilation and stents, therefore, the patients with RBES may have negative long-term results. Stents therapy tended to not reduce the times and frequency of dilation. Disclosure All authors have declared no conflicts of interest.


Author(s):  
Theodore H Stathos ◽  
Steven S Rothenberg ◽  
Aziz J Yazdi ◽  
Jose M Barrios ◽  
Sandra Kay

2003 ◽  
Vol 23 (5) ◽  
pp. 794-798 ◽  
Author(s):  
Alpay Sarper ◽  
Necdet Oz ◽  
Cemalettin Cihangir ◽  
Abid Demircan ◽  
Erol Isin

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