Erratum: Corrigendum: Cannabinoids and Capsaicin Improve Liver Function Following Thioacetamide-Induced Acute Injury in Mice

2009 ◽  
Vol 104 (3) ◽  
pp. 801-801
Author(s):  
Yosefa Avraham ◽  
Olga Zolotarev ◽  
Nikolaos C Grigoriadis ◽  
Theofilos Pautahidis ◽  
Iddo Magen ◽  
...  
Keyword(s):  
Liver Function ◽  
Acute Injury ◽  
Improve Liver Function

Cannabinoids and Capsaicin Improve Liver Function Following Thioacetamide-Induced Acute Injury in Mice

2008 ◽  
Vol 103 (12) ◽  
pp. 3047-3056 ◽  
Author(s):  
Yosefa Avraham ◽  
Olga Zolotarev ◽  
Nikolaos C. Grigoriadis ◽  
Theofilos Pautahidis ◽  
Iddo Magen ◽  
...  
Keyword(s):  
Liver Function ◽  
Acute Injury ◽  
Improve Liver Function

scholarly journals The Effects of High-Dose Qinggan Huoxue Recipe on Acute Liver Failure Induced by D-Galactosamine in Rats

2013 ◽  
Vol 2013 ◽  
pp. 1-8 ◽  
Author(s):  
Hong Zhu ◽  
Yang Zhang ◽  
Xiaoyu Hu ◽  
Cheng Yi ◽  
Sen Zhong ◽  
...  
Keyword(s):  
Liver Function ◽  
Liver Failure ◽  
Acute Liver Failure ◽  
Survival Curve ◽  
Survival Rates ◽  
High Mobility ◽  
Nuclear Antigen ◽  
High Dose ◽  
Improve Liver Function ◽  
Proliferating Cell

Qinggan Huoxue Recipe is a traditional Chinese medicine, which has been usually used to improve liver function in hepatitis. In order to investigate the effects of high-dose Qinggan Huoxue Recipe on acute liver failure and explore the potential mechanism, we had built acute liver failure models in rats by intraperitoneal injection of D-galactosamine (D-GalN). High-dose Qinggan Huoxue Recipe was delivered by gavage. After treatment, the blood alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL), albumin (ALB), cholinesterase (CHE), and prothrombin time (PT) were determined. The pathological score of liver tissue was recorded. Proliferating cell nuclear antigen (PCNA) immunohistochemistry staining and fluorescence quantitative reverse transcription polymerase chain reaction (qRT-PCR) of high mobility group box 1 (HMGB1), toll-like receptor 4 (TLR4), nuclear factor-kappa B (NF-κB), and Caspase-3 were performed. The survival curve was also depicted. Our results demonstrated that high-dose Qinggan Huoxue Recipe could significantly improve liver function and increase survival rates in rats with acute liver failure. These effects were supposed to be mediated by suppressing inflammatory reaction and apoptosis.

scholarly journals Does a fish-oil-containing lipid emulsion improve liver function in comparison with a soybean oil lipid emulsion?

Critical Care ◽  
2010 ◽  
Vol 14 (Suppl 1) ◽  
pp. P565
Author(s):  
J Linke ◽  
H Topp ◽  
I Mueller ◽  
S Bark ◽  
N Mertes ◽  
...  
Keyword(s):  
Liver Function ◽  
Fish Oil ◽  
Soybean Oil ◽  
Lipid Emulsion ◽  
Improve Liver Function

scholarly journals Outcomes of combination treatment with MARS and TIPS for hepatic veno-occlusive disease: a report of 12 cases

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052098087
Author(s):  
Li Deng ◽  
Xiuli Yin ◽  
Yingying Zhao ◽  
Jing Yang ◽  
Hongli Yang ◽  
...  
Keyword(s):  
Liver Function ◽  
Combination Treatment ◽  
Acute Liver Injury ◽  
Venous Pressure ◽  
Liver Function Tests ◽  
Portosystemic Shunt ◽  
Occlusive Disease ◽  
Full Recovery ◽  
Improve Liver Function ◽  
Intrahepatic Portosystemic Shunt

Background In patients with acute liver injury caused by hepatic veno-occlusive disease (HVOD), molecular adsorbent recirculation system (MARS) may be used to improve liver function in conjunction with transjugular intrahepatic portosystemic shunt (TIPS) to reduce portal hypertension. Methods Twelve patients were admitted to our hospital following treatment for HVOD for 10 to 21 days at other hospitals. All patients were treated with a combination of MARS and TIPS, and they were evaluated clinically including liver function tests. Results After the initial treatment with MARS, liver function improved significantly in all patients. TIPS placement decreased the hepatic venous pressure gradient (HVPG) to 10.17 ± 2.26 mmHg from a pre-TIPS HVPG of 23.58 ± 9.43 mmHg. The outcomes of combination treatment with MARS and TIPS in 12 patients with HVOD were as follows: 1) improvement of various clinical and biological parameters leading to full recovery in 1 year in 6 patients; 2) full recovery following liver transplantation for acute liver failure in three patients; and 3) three patients died due to hepatic failure after TIPS placement. Conclusion The combination of MARS and TIPS creation is promising as a potential treatment for acute HVOD, and it showed an improvement in overall survival.

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