scholarly journals Biological effect of human serum collected before and after oral intake of Pygeum africanum on various benign prostate cell cultures

2011 ◽  
Vol 14 (3) ◽  
pp. 499-504 ◽  
Author(s):  
Stéphane Larré ◽  
Philippe Camparo ◽  
Eva Comperat ◽  
Delphine Boulbés ◽  
Mohammed Haddoum ◽  
...  
Keyword(s):  
Human Serum ◽  
Cell Cultures ◽  
Biological Effect ◽  
Oral Intake ◽  
Prostate Cell ◽  
Before And After ◽  
Benign Prostate ◽  
Pygeum Africanum

Detection of dengue virus from mosquito cell cultures inoculated with human serum in the presence of actinomycin D

1995 ◽  
Vol 89 (2) ◽  
pp. 189-190
Author(s):  
Celso Ramos ◽  
Jorge M. Villaseca ◽  
Herlinda García ◽  
Dalia G. Hernández ◽  
José Ramos-Castañeda ◽  
...  
Keyword(s):  
Dengue Virus ◽  
Human Serum ◽  
Cell Cultures ◽  
Actinomycin D ◽  
Mosquito Cell

EP.TU.571Is the pen mightier than the scalpel? Improving the quality and efficiency of Major Trauma ward rounds

2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Ethlinn Patton ◽  
Dapo Olaleye ◽  
Stella Smith
Keyword(s):  
Adverse Events ◽  
Major Trauma ◽  
Current Practice ◽  
Oral Intake ◽  
Cost Effective ◽  
Poor Quality ◽  
Ward Round ◽  
Before And After ◽  
Ward Rounds ◽  
Gathering Data

Abstract Aims Methods Data was collected retrospectively between October to December 2020. Patient paper notes were reviewed on three dates before and after implementation of the ward round sticker, gathering data from 26 and 27 patients respectively. Data was collected across a series of weeks to ensure a variety of clinicians present on ward round, in order to accurately reflect current practice. Results An improvement in rate of documentation was seen in 10 out of 12 key clinical variables. Some of the largest increases were seen in consideration of VTE status; 96.3% (n = 26) from 7.69% (n = 2), and recording oral intake; 85.2% (n = 23) from 23.1% (n = 6.) Conclusions We know that poor quality documentation is associated with increased rates of adverse events for patients,[1] so it is imperative to address both what is being covered, and how it is being recorded. Staff reported that the use of ward round stickers improved legibility of documentation and made it easier to locate important information. This simple, cost effective intervention has improved the consistency of daily reviews, and streamlined communication within the multidisciplinary team.

scholarly journals Role of preoperative cervical alignment on postoperative dysphagia after occipitocervical fusion

2021 ◽  
Vol 12 ◽  
pp. 350
Author(s):  
Midori Miyagi ◽  
Hiroshi Takahashi ◽  
Hideki Sekiya ◽  
Satoru Ebihara
Keyword(s):  
Rank Correlation ◽  
Oral Intake ◽  
Postoperative Dysphagia ◽  
Occipitocervical Fusion ◽  
Cervical Alignment ◽  
Pharyngeal Airway ◽  
Before And After ◽  
Functional Oral Intake Scale ◽  
Relationship Of

Background: Dysphagia is one of the most serious complications of occipitocervical fusion (OCF). The previous studies have shown that postoperative cervical alignment, documented with occipito (O)-C2 angles, C2-C6 angles, and pharyngeal inlet angles (PIA), impacted the incidence of postoperative dysphagia in patients undergoing OCF. Here, we investigated the relationship of preoperative versus postoperative cervical alignment on the incidence of postoperative dysphagia after OCF. Methods: We retrospectively reviewed the clinical data/medical charts for 22 patients following OCF (2006– 2019). The O-C2 angles, C2-C6 angles, PIA, and narrowest pharyngeal airway spaces (nPAS) were assessed using plain lateral radiographs of the cervical spine before and after the surgery. The severity of dysphagia was assessed with the functional oral intake scale (FOIS) levels as documented in medical charts; based on this, patients were classified into the nondysphagia (FOIS: 7) versus dysphagia (FOIS: 1–6) groups. Results: Seven patients (35%) experienced dysphagia after OCF surgery. Preoperative PIA and nPAS were smaller in the dysphagia group. Spearman rank correlation showed a positive correlation between preoperative PIA and FOIS and between preoperative nPAS and FOIS. Conclusion: This study suggests that preoperative cervical alignment may best predict the incidence of postoperative dysphagia after OCF.

scholarly journals CLINICAL EVALUATION OF THE EFFICACY OF LEKHANBASTI AND MEDOHARAVIDANGADILAUHA IN THE MANAGEMENT OF DYSLIPIDEMIA

2021 ◽  
Vol 9 (7) ◽  
pp. 1362-1365
Author(s):  
Noor Sayeda Shabnam Ahmed ◽  
Om Prakash Gupta ◽  
Bishnu Prasad Sarma
Keyword(s):  
Lipid Profile ◽  
Clinical Evaluation ◽  
Oral Intake ◽  
Before And After ◽  
Significant Change ◽  
Ethical Clearance

This study was conducted to evaluate the efficacy of lekhanbasti and medoharavidangadilauha in the management of dyslipidemia. Consent from all the selected patients was taken before the study after explaining to them about the disease and the procedure. Ethical clearance was accredited by the ethical committee of Government Ayurvedic College and Hospital Guwahati, Assam. Patients from IPD and OPD of the department of Kayachikitsa of the aforesaid institute were chosen. Lekhanbasti niruha and tiltaila anuvasana on alternate days was administered for 8 days Follow up was done at an interval of 30,60 and 90 days. Oral intake of medoharavidangadilauha was advised during these 90 days. The basti was repeated in the follow-up period. After comparing the fasting lipid profile before and after treatment it was found that there was a significant change in it. Keywords: Dyslipidemia, Lekhanbasti, Medoharavidangadilauha, Medoroga, Fasting lipid profile.

scholarly journals Short-term variability of the human serum metabolome depending on nutritional and metabolic health status

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Inoncent Agueusop ◽  
Petra B. Musholt ◽  
Beate Klaus ◽  
Kendra Hightower ◽  
Aimo Kannt
Keyword(s):  
Human Serum ◽  
Individual Variability ◽  
Metabolic Health ◽  
Serum Samples ◽  
Controlled Conditions ◽  
Single Center Study ◽  
Before And After ◽  
Study Participants ◽  
Intra Class Correlation Coefficient

Abstract The intra-individual variability of the human serum metabolome over a period of 4 weeks and its dependence on metabolic health and nutritional status was investigated in a single-center study under tightly controlled conditions in healthy controls, pre-diabetic individuals and patients with type-2 diabetes mellitus (T2DM, n = 10 each). Untargeted metabolomics in serum samples taken at three different days after overnight fasts and following intake of a standardized mixed meal showed that the human serum metabolome is remarkably stable: The median intra-class correlation coefficient (ICC) across all metabolites and all study participants was determined as 0.65. ICCs were similar for the three different health groups, before and after meal intake, and for different metabolic pathways. Only 147 out of 1438 metabolites (10%) had an ICC below 0.4 indicating poor stability over time. In addition, we confirmed previously identified metabolic signatures differentiating healthy, pre-diabetic and diabetic individuals. To our knowledge, this is the most comprehensive study investigating the temporal variability of the human serum metabolome under such tightly controlled conditions.

Oral D-Aspartate enhances synaptic plasticity reserve in progressive multiple sclerosis

2019 ◽  
Vol 26 (3) ◽  
pp. 304-311 ◽  
Author(s):  
Carolina G Nicoletti ◽  
Fabrizia Monteleone ◽  
Girolama A Marfia ◽  
Alessandro Usiello ◽  
Fabio Buttari ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Synaptic Plasticity ◽  
Cortical Excitability ◽  
Short Interval ◽  
Oral Intake ◽  
Long Term Potentiation ◽  
Progressive Multiple Sclerosis ◽  
Clinical Effects ◽  
Term Potentiation ◽  
Before And After

Background: Synaptic plasticity reserve correlates with clinical recovery after a relapse in relapsing–remitting forms of multiple sclerosis (MS) and is significantly compromised in patients with progressive forms of MS. These findings suggest that progression of disability in MS is linked to reduced synaptic plasticity reserve. D-Aspartate, an endogenous aminoacid approved for the use in humans as a dietary supplement, enhances synaptic plasticity in mice. Objective: To test whether D-Aspartate oral intake increases synaptic plasticity reserve in progressive MS patients. Methods: A total of 31 patients affected by a progressive form of MS received either single oral daily doses of D-Aspartate 2660 mg or placebo for 4 weeks. Synaptic plasticity reserve and trans-synaptic cortical excitability were measured through transcranial magnetic stimulation (TMS) protocols before and after D-Aspartate. Results: Both TMS-induced long-term potentiation (LTP), intracortical facilitation (ICF) and short-interval ICF increased after 2 and 4 weeks of D-Aspartate but not after placebo, suggesting an enhancement of synaptic plasticity reserve and increased trans-synaptic glutamatergic transmission. Conclusion: Daily oral D-Aspartate 2660 mg for 4 weeks enhances synaptic plasticity reserve in patients with progressive MS, opening the path to further studies assessing its clinical effects on disability progression.

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