scholarly journals Uptake of resveratrol and role of resveratrol-targeting protein, quinone reductase 2, in normally cultured human prostate cells

2009 ◽  
Vol 11 (6) ◽  
pp. 653-661 ◽  
Author(s):  
Tze-Chen Hsieh
Keyword(s):  
Quinone Reductase ◽  
Human Prostate ◽  
Quinone Reductase 2 ◽  
Prostate Cells

scholarly journals Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives

Molecules ◽  
2017 ◽  
Vol 22 (2) ◽  
pp. 210 ◽  
Author(s):  
Laure-Estelle Cassagnes ◽  
Nambinina Rakotoarivelo ◽  
Serena Sirigu ◽  
Pierre Pério ◽  
Ennaji Najahi ◽  
...  
Keyword(s):  
Quinone Reductase ◽  
Quinone Reductase 2

scholarly journals Role of Hormonal and Other Factors in Human Prostate Cancer

2008 ◽  
Vol 11 (3-4) ◽  
pp. 242-259 ◽  
Author(s):  
Donald T. Wigle ◽  
Michelle C. Turner ◽  
James Gomes ◽  
Marie-Élise Parent
Keyword(s):  
Prostate Cancer ◽  
Human Prostate ◽  
Human Prostate Cancer

scholarly journals Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells

2014 ◽  
Vol 1843 (9) ◽  
pp. 1839-1850 ◽  
Author(s):  
Yuyang Sun ◽  
Pramod Sukumaran ◽  
Archana Varma ◽  
Susan Derry ◽  
Abe E. Sahmoun ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Human Prostate ◽  
Prostate Cells

Metal-Containing Proteins in the Apoptosis and Redox Processes in the Rat Prostate and Human Prostate Cells

2006 ◽  
Vol 1090 (1) ◽  
pp. 113-119
Author(s):  
I GRBAVAC ◽  
C WOLF ◽  
N WENDA ◽  
D ALBER ◽  
M KUHBACHER ◽  
...  
Keyword(s):  
Human Prostate ◽  
Redox Processes ◽  
Prostate Cells ◽  
Rat Prostate

MP-03.01 Functional Role of PGP 9.5 as Tumor Suppressor is Inactivated by Promoter CpG Methylation in Human Prostate Cancer

Urology ◽  
2011 ◽  
Vol 78 (3) ◽  
pp. S41
Author(s):  
Y. Mitsui ◽  
M. Hiraki ◽  
N. Arichi ◽  
T. Hiraoka ◽  
M. Sumura ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Tumor Suppressor ◽  
Functional Role ◽  
Cpg Methylation ◽  
Human Prostate ◽  
Human Prostate Cancer ◽  
Pgp 9.5

scholarly journals A Novel Role of Myosin VI in Human Prostate Cancer

2006 ◽  
Vol 169 (5) ◽  
pp. 1843-1854 ◽  
Author(s):  
Thomas A. Dunn ◽  
Shenglin Chen ◽  
Dennis A. Faith ◽  
Jessica L. Hicks ◽  
Elizabeth A. Platz ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Human Prostate ◽  
Myosin Vi ◽  
Human Prostate Cancer

scholarly journals Androgen receptor localisation and turnover in human prostate epithelium treated with the antiandrogen, casodex

2000 ◽  
Vol 24 (3) ◽  
pp. 339-351 ◽  
Author(s):  
AS Waller ◽  
RM Sharrard ◽  
P Berthon ◽  
NJ Maitland
Keyword(s):  
Androgen Receptor ◽  
In Vitro Models ◽  
Human Prostate ◽  
Intracellular Targeting ◽  
Natural Ligand ◽  
Prostate Cells ◽  
Established Cell ◽  
Prostatic Epithelium ◽  
Prostate Epithelium

In vitro models of normal and malignant human prostate are currently limited to a few well established cell lines that, with a single exception (LNCaP), fail to express the androgen receptor (AR) - a common characteristic of prostatic epithelium grown in culture. To investigate the molecular mechanism of action of the non-steroidal antiandrogen Casodex (bicalutamide) against wild-type AR, we have established a transient AR expression model in non-tumorigenic prostate cells of both epithelial and mesenchymal origin. In this model, both dihydrotestosterone and Casodex can effectively transport the AR protein into the nucleus of prostate cells. Whereas the natural ligand, dihydrotestosterone, stabilises the receptor, the AR is rapidly degraded at a nuclear location when the transfected cells are treated with Casodex. In contrast, whereas the mutant AR in the LNCaP line is also degraded on Casodex treatment over the same time period, its intracellular targeting is defective.

Sign in / Sign up

Export Citation Format

Share Document