Embryonic stem cell lines from human blastocysts: somatic differentiation in vitro

10.1038/74447 ◽  
2000 ◽  
Vol 18 (4) ◽  
pp. 399-404 ◽  
Author(s):  
Benjamin E. Reubinoff ◽  
Martin F. Pera ◽  
Chui-Yee Fong ◽  
Alan Trounson ◽  
Ariff Bongso
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Stem Cell Lines

scholarly journals Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin

2011 ◽  
Vol 21 (4) ◽  
pp. 751-764 ◽  
Author(s):  
Silvia V. Diaz Perez ◽  
Rachel Kim ◽  
Ziwei Li ◽  
Victor E. Marquez ◽  
Sanjeet Patel ◽  
...  
Keyword(s):  
Stem Cell ◽  
Chemical Modification ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Lines

Chromosomal integrity maintained in five human embryonic stem cell lines after prolonged in vitro culture

2006 ◽  
Vol 14 (2) ◽  
pp. 131-137 ◽  
Author(s):  
Gunilla Caisander ◽  
Hannah Park ◽  
Katarina Frej ◽  
Jenny Lindqvist ◽  
Christina Bergh ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
In Vitro Culture ◽  
Cell Lines ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Stem Cell Lines

ESTABLISHMENT OF EMBRYONIC STEM CELL LINES DERIVED FROM IN VITRO-PRODUCED BUFFALO (Bubalus bubalis) EMBRYOS

2007 ◽  
Vol 77 (Suppl_1) ◽  
pp. 186-187
Author(s):  
Vinod Verma ◽  
Sanjeev Gautam ◽  
Manmohansingh Chauhan ◽  
Radheyshyam Manik ◽  
Prabhat Palta ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Bubalus Bubalis ◽  
Stem Cell Lines

scholarly journals Pluripotent pig embryonic stem cell lines originating from in vitro-fertilized and parthenogenetic embryos

2020 ◽  
Vol 49 ◽  
pp. 102093
Author(s):  
Kwang-Hwan Choi ◽  
Dong-Kyung Lee ◽  
Jong-Nam Oh ◽  
Seung-Hun Kim ◽  
Mingyun Lee ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Stem Cell Lines ◽  
Parthenogenetic Embryos

scholarly journals Derivation and Characterization of Canine Embryonic Stem Cell Lines with In Vitro and In Vivo Differentiation Potential.

2010 ◽  
Vol 83 (Suppl_1) ◽  
pp. 203-203
Author(s):  
Margaret R. Hough ◽  
Andrea K. Vaags ◽  
Anderson Goncalves ◽  
Cathy J. Gartley ◽  
Yanzhen Zheng ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Differentiation Potential ◽  
In Vivo Differentiation ◽  
Stem Cell Lines

scholarly journals Derivation and Characterization of Canine Embryonic Stem Cell Lines with In Vitro and In Vivo Differentiation Potential

Stem Cells ◽  
2009 ◽  
Vol 27 (2) ◽  
pp. 329-340 ◽  
Author(s):  
Andrea K. Vaags ◽  
Suzana Rosic-Kablar ◽  
Cathy J. Gartley ◽  
Yan Zhen Zheng ◽  
Alden Chesney ◽  
...  
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Differentiation Potential ◽  
In Vivo Differentiation ◽  
Stem Cell Lines

scholarly journals Patentability of the Human Embryonic Stem Cell Lines: A Legal and Ethical Aspect

2020 ◽  
Author(s):  
Tansu Sayar Kanyış ◽  
Ezgi Arslan ◽  
Oğuzhan Kanyış
Keyword(s):  
Stem Cells ◽  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Human Embryo ◽  
Human Embryonic Stem Cell ◽  
Embryonic Stem ◽  
Point Of View ◽  
Stem Cell Lines

In this study, patentability of the human embryonic stem cell lines has discussed in the legal and ethical perspectives. In vitro human embryonic stem cells can be defined as body parts that are departed from the body. Human embryonic stem cell lines are constituted of differentiated self-renewal pluripotent stem cells, which means they have no characteristics to become a human-being. However, interpreting the terms like human embryo and right to property widely can cause the human embryonic stem cell lines are misunderstood as unpatentable. For our point of view, giving the human embryo the protections of both personal rights of the donor and the right to property of the owner of the invention does not reduce the legal/moral status of the human embryo. Besides, the obligations which these rights imposes to their owners, such as the principle of human dignity and prohibition of financial gain can protect the human embryo in a better way.

The in vitro development of blastocyst-derived embryonic stem cell lines: formation of visceral yolk sac, blood islands and myocardium

Development ◽  
1985 ◽  
Vol 87 (1) ◽  
pp. 27-45
Author(s):  
Thomas C. Doetschman ◽  
Harald Eistetter ◽  
Margot Katz ◽  
Werner Schmidt ◽  
Rolf Kemler
Keyword(s):  
Stem Cell ◽  
Embryonic Stem Cell ◽  
Cell Lines ◽  
Embryonic Stem ◽  
Yolk Sac ◽  
Embryoid Bodies ◽  
Developmental Potential ◽  
Visceral Yolk Sac ◽  
Stem Cell Lines

The in vitro developmental potential of mouse blastocyst-derived embryonic stem cell lines has been investigated. From 3 to 8 days of suspension culture the cells form complex embryoid bodies with endoderm, basal lamina, mesoderm and ectoderm. Many are morphologically similar to embryos of the 6- to 8-day egg-cylinder stage. From 8 to 10 days of culture about half of the embryoid bodies expand into large cystic structures containing alphafoetoprotein and transferrin, thus being analagous to the visceral yolk sac of the postimplantation embryo. Approximately one third of the cystic embryoid bodies develop myocardium and when cultured in the presence of human cord serum, 30 % develop blood islands, thereby exhibiting a high level of organized development at a very high frequency. Furthermore, most embryonic stem cell lines observed exhibit similar characteristics. The in vitro developmental potential of embryonic stem cell lines and the consistency with which the cells express this potential are presented as aspects which open up new approaches to the investigation of embryogenesis.

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