Most classical Mus musculus domesticus laboratory mouse strains carry a Mus musculus musculus Y chromosome

Nature ◽  
1985 ◽  
Vol 315 (6014) ◽  
pp. 70-72 ◽  
Author(s):  
C. E. Bishop ◽  
P. Boursot ◽  
B. Baron ◽  
F. Bonhomme ◽  
D. Hatat
Keyword(s):  
Y Chromosome ◽  
Mus Musculus ◽  
Laboratory Mouse ◽  
Mouse Strains ◽  
Mus Musculus Domesticus ◽  
Mus Musculus Musculus

Analyse génétique de la zone d'hybridation entre les deux sous-espèces de souris Mus musculus domesticus et Mus musculus musculus en Bulgarie

Genome ◽  
1988 ◽  
Vol 30 (3) ◽  
pp. 427-437 ◽  
Author(s):  
Flavie Vanlerberghe ◽  
Pierre Boursot ◽  
Josette Catalan ◽  
Svestoslav Gerasimov ◽  
François Bonhomme ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Y Chromosome ◽  
Hybrid Zone ◽  
Mus Musculus ◽  
Functional Differentiation ◽  
Restriction Pattern ◽  
The Black Sea ◽  
Mus Musculus Domesticus ◽  
The Balkans ◽  
Mus Musculus Musculus

The hybrid zone between the two subspecies of mice Mus musculus domesticus and Mus musculus musculus, which has been studied extensively in Denmark, crosses Europe to the Black Sea through the Alps and the Balkans. Two hundred and seventy-nine animals were captured in 22 localities along a transect across the Balkans. The animals were characterized for seven diagnostic nuclear loci by protein electrophoresis and by restriction pattern analysis of their mitochondrial DNA. The nuclear data show a sharp transition between the two subspecies, most of the variations in allele frequencies (from 0.9 to 0.1) occurring within a 36-km section of the transect. The introgression varies from one locus to the other and is more pronounced, in terms of distance, in M. m. musculus territory. Mitochondrial DNA introgression is important but occurs in one direction only, i.e. from M. m. musculus to M. m. domesticus, while a cytoplasmic transfer from M. m. domesticus to M. m. musculus has been reported. A previous study showed that no Y chromosome introgression occurs. The different behaviour of these three types of markers could be due to the interaction between selection against hybrid genomes and meiotic recombination. Objectively, it would appear that the genes that can introgress are neutral or nearly so and have been separated from deleterious genes they were linked to by recombination. This could explain the differential introgression between autosomal loci. The mitochondrial and Y chromosomes undergo no or very little recombination and each is transmitted as a whole. Their degree of introgression is thus indicative of the intensity of selection resulting from the amount of functional differentiation between the two taxa, which seems to be strong for the Y chromosome and weak for mitochondrial DNA. We propose that the asymmetry of nuclear introgression is due to different population structures. As M. m. musculus is relatively less structured, the rapid spreading of introgressed genes would be favoured. Such a scheme, however, can hardly account for the unidirectionality of the mitochondrial flow, which could be due to sex-dependant behaviour.Key words: mice, hybrid zone, introgression, enzyme polymorphism.

The Mus musculus domesticus Tdy allele acts later than the Mus musculus musculus Tdy allele: a basis for XY sex-reversal in C57BL/6-YPOS mice

Development ◽  
1991 ◽  
Vol 113 (2) ◽  
pp. 709-714 ◽  
Author(s):  
S.J. Palmer ◽  
P.S. Burgoyne
Keyword(s):  
Y Chromosome ◽  
Mus Musculus ◽  
Limb Development ◽  
Inbred Strains ◽  
Testicular Development ◽  
Mus Musculus Domesticus ◽  
Mus Musculus Musculus ◽  
Testicular Differentiation ◽  
Allelic Differences ◽  
Xy Sex Reversal

Consomic C57BL/6 males, carrying either the Mus musculus musculus-derived C57BL/6 Y chromosome or the Mus musculus domesticus-derived Poschiavinus Y chromosome, were outcrossed to females of the inbred strains C3H/Bi and CXBH/By and to females of the random bred strain MF1/Ola. In a study at 12.5 days post coitum, gonads of XYC57 and XYPOS fetuses were assessed for the presence of testicular cords. It was found that XYPOS fetuses had a later onset of testicular development than XYC57 fetuses. Limb development, which was monitored as a measure of overall development, was unaffected by the strain of Y present. These data were supported by a longitudinal study in which the increased growth rate of the testes relative to undifferentiated gonads, was also shown to be delayed in XYPOS fetuses. The extent of the delay was estimated to be approximately 14 h. It is concluded that this delay in the onset of testicular differentiation must be caused by differences between the two Y-chromosome types, most probably allelic differences in the testis determinant Tdy.

scholarly journals Host subspecific viral strains in European house mice: Murine cytomegalovirus in the Eastern (Mus musculus musculus) and Western house mouse (Mus musculus domesticus)

Virology ◽  
2018 ◽  
Vol 521 ◽  
pp. 92-98 ◽  
Author(s):  
Dagmar Čížková ◽  
Stuart J.E. Baird ◽  
Jana Těšíková ◽  
Sebastian Voigt ◽  
Ďureje Ľudovít ◽  
...  
Keyword(s):  
House Mouse ◽  
Mus Musculus ◽  
Murine Cytomegalovirus ◽  
House Mice ◽  
Mus Musculus Domesticus ◽  
Mus Musculus Musculus

Two types of mouse (Mus musculus domesticus) Y chromosomes in Quebec

Genome ◽  
1992 ◽  
Vol 35 (3) ◽  
pp. 534-537
Author(s):  
Yutaka Nishioka
Keyword(s):  
Y Chromosome ◽  
House Mouse ◽  
Mus Musculus ◽  
Repetitive Sequence ◽  
The Other ◽  
Chromosome Polymorphism ◽  
Mus Musculus Domesticus ◽  
Y Chromosomes

A Y chromosomal repetitive sequence identified two types of Y chromosomes in mice (Mus musculus domesticus) caught near Ste. Anne de Bellevue, Quebec. One type is apparently identical to the Y chromosome found in Maryland, Delaware, and California, whereas the other type is similar, but not identical, to the Y chromosome present in M.m. poschiavinus, an Alpine race of M.m. domesticus. These findings suggest that the domesticus Y chromosome is highly polymorphic and thus useful for elucidating the relationships among American and European house mouse populations.Key words: mouse Y chromosome, polymorphism, Mus musculus domesticus, repetitive sequence, Quebec.

scholarly journals Esterase alleles of inbred mouse strains maintained in The Netherlands

1988 ◽  
Vol 51 (1) ◽  
pp. 29-40 ◽  
Author(s):  
J. Hilgers ◽  
O. von Deimling ◽  
L. F. M. van Zutphen ◽  
R. ten Berg ◽  
R. Anand ◽  
...  
Keyword(s):  
Mus Musculus ◽  
Inbred Mouse ◽  
Chromosome 8 ◽  
Mouse Strains ◽  
Inbred Mouse Strains ◽  
Laboratory Mice ◽  
Mus Musculus Domesticus ◽  
Chinese Origin ◽  
Esterase Loci ◽  
Quantitative Manner

SummaryFifty-seven mouse strains were examined for genetic variation at 21 esterase loci. Three new alleles were found: Es-6d in strain A/WySna, Es-lle in FTC/CpbU and Es-18c in two WLL/BrA sublines. At most loci there was a single allele found in over 80% of strains, with one or two rare alleles. However, the Es-1, 3, 10, 13, 25 and 27 loci were much more polymorphic. Although several loci were linked on chomosomes 3, 8 and 9, linkage disequilibrium was only found between Es-5 and Es-11 (chromosome 8) and Es-26 and Es-27 (chromosome 3). There was also significant disequilibrium between Es-1 and 3, Es-1 and 10, and Es-3 and 10, which are on different chromosomes, suggesting that the 57 strains are not a random sample of inbred mouse strains. Fifty-four strains were closely related, with the Es-7b, –17a, –18a, –23c set of alleles, which are typical of Mus musculus domesticus. The three exceptional strains were MOL3 (Mus musculus molossinus), WLL/BrA (English–Norwegian origin) and TA2 (Chinese origin). There were 10 groups of strains which were identical at all loci. Sublines of the same strain were usually identical. Sometimes more distantly related strains, such as CBA/Bi, C3H/He, SM and DBA/Li, were identical, and in a few cases strains with no known common ancestry such as C58 and MAS were identical. Attempts to discriminate between a subset of 22 American and 15 European strains were unsuccessful, suggesting that the European strains add only in a quantitative manner to the gene pool of ‘laboratory mice’, whereas wild-derived strains such as MOL3 are genetically quite distinct from other laboratory mice.

scholarly journals The Mus musculus musculus type Y chromosome predominates in Asian house mice

1987 ◽  
Vol 50 (3) ◽  
pp. 195-198 ◽  
Author(s):  
Yutaka Nishioka ◽  
Estelle Lamothe
Keyword(s):  
Y Chromosome ◽  
Mus Musculus ◽  
Repetitive Sequence ◽  
House Mice ◽  
Jackson Laboratory ◽  
Mus Musculus Musculus

SummaryUsing a mouse Y chromosomal repetitive sequence that differentiates between the Mus musculus musculus type Y chromosome and the M. m. domesticus type Y chromosome, we studied the Y chromosome in M. m. molossinus, M. m. castaneus and M. m. subspecies specimens recently trapped in Japan, Taiwan and China as well as Asian mice maintained at the Jackson Laboratory and Litton Bionetics. Here we report that the M. m. musculus type Y chromosome predominates in Asian house mice and that Japanese mice maintained at some laboratories may not represent typical M. m. molossinus.

scholarly journals Y-chromosomal DNA polymorphism in mouse inbred strains

1987 ◽  
Vol 50 (1) ◽  
pp. 69-72 ◽  
Author(s):  
Yutaka Nishioka
Keyword(s):  
Y Chromosome ◽  
Mus Musculus ◽  
Dna Polymorphism ◽  
Inbred Strains ◽  
Laboratory Mice ◽  
Wild Populations ◽  
Chromosomal Dna ◽  
Mus Musculus Musculus

SummaryMice are the most widely used experimental mammals, and many inbred strains are available. However, except for the relatively recent strains derived from known wild populations, the relationships between wild and laboratory mice are not well understood. Based on the Y-chromosomal restriction fragmentlength polymorphism, seventeen inbred strains were classified into two groups: strains with the Mus musculus musculus type Y chromosome and those with the M. m. domesticus type Y chromosome. We extended the survey to an additional twenty-two inbred strains. The M. m. musculus type Y chromosome was found in AEJ/GnLe, AAU/SsJ, BDP/J, BXSB/MpJ, DA/HuSn, HTG/GoSfSn, I/LnJ, LP/J, NZW/LacJ, RIIIS/J, SB/Le, SEA/GnJ, SF/CamEi, SK/CamEi, SM/J, WB/ReJ, WC/ReJ and YBR/Ei, while the M. m. domesticus type Y chromosome was present in BUB/BnJ, MA/MyJ, PL/J and ST/bJ.

scholarly journals Mitochondrial DNA in the hybrid zone between Mus musculus musculus and Mus musculus domesticus: a comparison of two transects

2005 ◽  
Vol 84 (3) ◽  
pp. 363-378 ◽  
Author(s):  
EVA BOŽÍKOVÁ ◽  
PAVEL MUNCLINGER ◽  
KATHERINE C. TEETER ◽  
PRISCILLA K. TUCKER ◽  
MILOŠ MACHOLÁN ◽  
...  
Keyword(s):  
Mitochondrial Dna ◽  
Hybrid Zone ◽  
Mus Musculus ◽  
Mus Musculus Domesticus ◽  
Mus Musculus Musculus
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