Induction by cyclic GMP of cationic conductance in plasma membrane of retinal rod outer segment

Nature ◽  
1985 ◽  
Vol 313 (6000) ◽  
pp. 310-313 ◽  
Author(s):  
Evgeniy E. Fesenko ◽  
Stanislav S. Kolesnikov ◽  
Arkadiy L. Lyubarsky
Keyword(s):  
Plasma Membrane ◽  
Cyclic Gmp ◽  
Outer Segment ◽  
Rod Outer Segment ◽  
Retinal Rod

Tubulin in bovine retinal rod outer segments

1992 ◽  
Vol 103 (1) ◽  
pp. 157-166
Author(s):  
D.F. Matesic ◽  
N.J. Philp ◽  
J.M. Murray ◽  
P.A. Liebman
Keyword(s):  
Plasma Membrane ◽  
Outer Segment ◽  
Photoreceptor Cells ◽  
High Salt ◽  
Immunofluorescent Staining ◽  
Rod Outer Segments ◽  
Rod Outer Segment ◽  
Retinal Rod ◽  
Additional Role ◽  
Retinal Rod Outer Segments

Bovine rod outer segment (ROS) preparations contain a major 58 kDa protein doublet that was identified by immunoblot as tubulin. Quantification by gel densitometry showed that the total amount of tubulin was 5- to 10-fold higher than that attributable to the rod axoneme, suggesting additional role(s) for tubulin in photoreceptor cells. Approximately 20% of this nonaxonemal tubulin (15% of total tubulin) is tightly associated with outer segment membranes. This fraction remains membrane-associated after extensive low- or high-salt washing, requiring detergents or protein denaturants for release from ROS membranes. Unlike ROS soluble tubulin it associates tightly with liposomes upon detergent solubilization and reconstitution. The ROS membrane-associated tubulin is highly enriched in isolated ROS plasma membrane fractions compared to the total outer segment membrane pool and can be localized to the plasma membrane but not to disks by immunofluorescent staining, suggesting a possible role in the structure or electrophysiology of the rod outer segment plasma membrane.

Guanylate Cyclase of Retinal Rod Outer Segment

1990 ◽  
pp. 139-145
Author(s):  
I. M. Pepe ◽  
I. Panfoli ◽  
C. Cugnoli
Keyword(s):  
Guanylate Cyclase ◽  
Outer Segment ◽  
Rod Outer Segment ◽  
Retinal Rod

Evidence for aerobic metabolism in retinal rod outer segment disks

2009 ◽  
Vol 41 (12) ◽  
pp. 2555-2565 ◽  
Author(s):  
Isabella Panfoli ◽  
Daniela Calzia ◽  
Paolo Bianchini ◽  
Silvia Ravera ◽  
Alberto Diaspro ◽  
...  
Keyword(s):  
Outer Segment ◽  
Aerobic Metabolism ◽  
Rod Outer Segment ◽  
Retinal Rod
Sign in / Sign up

Export Citation Format

Share Document