Altered ribosomal RNA genes in mitochondria from mammalian cells with chloramphenicol resistance

Nature ◽  
1981 ◽  
Vol 290 (5807) ◽  
pp. 607-608 ◽  
Author(s):  
Stephen E. Kearsey ◽  
Ian W. Craig
2006 ◽  
Vol 84 (4) ◽  
pp. 444-439 ◽  
Author(s):  
Sui Huang ◽  
Lawrence I. Rothblum ◽  
Danyang Chen

Mammalian cells contain approximately 400 copies of the ribosomal RNA genes organized as tandem, head-to-tail repeats spread among 6–8 chromosomes. Only a subset of the genes is transcribed at any given time. Experimental evidence suggests that, in a specific cell type, only a fraction of the genes exists in a conformation that can be transcribed. An increasing body of study indicates that eukaryotic ribosomal RNA genes exist in either a heterochromatic nucleosomal state or in open euchromatic states in which they can be, or are, transcribed. This review will attempt to summarize our current understanding of the structure and organization of ribosomal chromatin.


1987 ◽  
Vol 8 (1) ◽  
pp. 3-12 ◽  
Author(s):  
R. A. Jorgensen ◽  
R. E. Cuellar ◽  
W. F. Thompson ◽  
T. A. Kavanagh

2013 ◽  
Vol 139 (2) ◽  
pp. 102-106 ◽  
Author(s):  
D.T. Hashimoto ◽  
M.A. Ferguson-Smith ◽  
W. Rens ◽  
F.D. Prado ◽  
F. Foresti ◽  
...  

1989 ◽  
Vol 36 ◽  
pp. 18s-20s ◽  
Author(s):  
JEFFREY C. EDMAN ◽  
JOSEPH A. KOVACS ◽  
HENRY MASUR ◽  
DANIEL V. SANTI ◽  
HILLE J. EL WOOD ◽  
...  

1989 ◽  
Vol 36 (1) ◽  
pp. 18S-20S ◽  
Author(s):  
JEFFREY C. EDMAN ◽  
JOSEPH A. KOVACS ◽  
HENRY MASUR ◽  
DANIEL V. SANTI ◽  
HILLE J. ELWOOD ◽  
...  

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