Synaptic remodelling in the mutant cerebellum

Nature ◽  
1975 ◽  
Vol 257 (5522) ◽  
pp. 86-87
Author(s):  
Shin-Ho Chung
Keyword(s):  
Mutant Cerebellum ◽  
Synaptic Remodelling

The N-CAM D2-protein as marker for synaptic remodelling in the red nucleus

1987 ◽  
Vol 405 (1) ◽  
pp. 39-45 ◽  
Author(s):  
Ole Steen Jørgensen ◽  
Jesper Mogensen ◽  
Ivan Divac
Keyword(s):  
Red Nucleus ◽  
D2 Protein ◽  
Synaptic Remodelling

The role of estradiol and progesterone in phased synaptic remodelling of the rat arcuate nucleus

1993 ◽  
Vol 608 (1) ◽  
pp. 38-44 ◽  
Author(s):  
Julio Pe´rez ◽  
Sonia Luqui´n ◽  
Frederick Naftolin ◽  
Luis Miguel Garci´a-Segura
Keyword(s):  
Arcuate Nucleus ◽  
Synaptic Remodelling

Neurotrophic factors, neuronal selectionism, and neuronal proliferation

1997 ◽  
Vol 20 (4) ◽  
pp. 561-562 ◽  
Author(s):  
T. Elliott ◽  
N. R. Shadbolt
Keyword(s):  
Neurotrophic Factors ◽  
Neuronal Development ◽  
Neuronal Proliferation ◽  
Synaptic Remodelling

Quartz & Sejnowski (Q&S) disregard evidence that suggests that their view of dendrites is inadequate and they ignore recent results concerning the role of neurotrophic factors in synaptic remodelling. They misrepresent neuronal selectionism and thus erect a straw-man argument. Finally, the results discussed in section 4.2 require neuronal proliferation, but this does not occur during the period of neuronal development of relevance here.

Embryonic and adult neurons interact to allow Purkinje cell replacement in mutant cerebellum

Nature ◽  
1987 ◽  
Vol 327 (6121) ◽  
pp. 421-423 ◽  
Author(s):  
Constantino Sotelo ◽  
Rosa Magda Alvarado-Mallart
Keyword(s):  
Purkinje Cell ◽  
Cell Replacement ◽  
Mutant Cerebellum

Spinocerebellar mossy fiber terminal topography in the NR2C/PKCγ double mutant cerebellum

1996 ◽  
Vol 97 (1) ◽  
pp. 138-142
Author(s):  
Zhongqi Ji ◽  
Alex Ebralidze ◽  
Susumu Tonegawa ◽  
Michael W. Vogel
Keyword(s):  
Double Mutant ◽  
Mossy Fiber ◽  
Mutant Cerebellum

Influence of experimentally induced agranularity on the synaptogenesis of serotonin nerve terminals in rat cerebellar cortex

1979 ◽  
Vol 206 (1162) ◽  
pp. 133-138 ◽  
Keyword(s):  
Cerebellar Cortex ◽  
Granular Layer ◽  
Granule Cells ◽  
Absolute Number ◽  
External Granular Layer ◽  
X Ray ◽  
Synaptic Contacts ◽  
Cellular Environment ◽  
Normal Controls ◽  
Synaptic Remodelling

The serotonin (5-HT) innervation of the posterior vermis was studied by high resolution radioautography in both normal and X-ray-induced agranular rat cerebella, following 3 h topical superfusion with 10 -4 M 3 H-5-HT. In the normal cerebellar cortex, 5-HT axonal varicosities are scarce and only rarely exhibit the membrane differentiations character­izing synaptic contacts. In the agranular cerebellum, 5-HT terminals ap­pear to have a much higher density than in normal controls, although their absolute number may not be significantly different when the import­ant reduction in volume of this experimental cerebellum is taken into account. These terminals frequently show typical synaptic contacts. Most of them are established on the branchlet spines of Purkinje cell dendrites, but some are also observed on the shafts of Golgi cell dendrites. The 5-HT innervation of the cerebellar cortex thus undergoes important changes in the absence of granule cells. It is suggested that these modifications may be part of the general reorganization process of the cerebellar circuitry consequent on the early destruction of the external granular layer. This new example of synaptic remodelling could imply that the formation of cerebellar connectivity is modulated, to a certain extent, by the local cellular environment.

Cholesterol synthesis and lipoprotein reuptake during synaptic remodelling in hippocampus in adult rats

Neuroscience ◽  
1993 ◽  
Vol 55 (1) ◽  
pp. 81-90 ◽  
Author(s):  
J. Poirier ◽  
A. Baccichet ◽  
D. Dea ◽  
S. Gauthier
Keyword(s):  
Cholesterol Synthesis ◽  
Adult Rats ◽  
Synaptic Remodelling
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