Opiate agonist-antagonist effects on Renshaw cells and spinal interneurones

Nature ◽  
1974 ◽  
Vol 250 (5461) ◽  
pp. 70-71 ◽  
Author(s):  
J. DAVIES ◽  
A. W. DUGGAN
Keyword(s):  
Renshaw Cells ◽  
Spinal Interneurones ◽  
Opiate Agonist

The responses of renshaw cells and spinal interneurones of the rat to l-glutamate and l-aspartate

1978 ◽  
Vol 141 (1) ◽  
pp. 129-136 ◽  
Author(s):  
G.B. Hutchinson ◽  
H. McLennan ◽  
H.V. Wheal
Keyword(s):  
Renshaw Cells ◽  
Spinal Interneurones

The sensitivity of rat spinal interneurones and Renshaw cells to L-glutamate and L-aspartate

1976 ◽  
Vol 26 (5) ◽  
Author(s):  
T.J. Biscoe ◽  
P.M. Headley ◽  
D. Lodge ◽  
M.R. Martin ◽  
J.C. Watkins
Keyword(s):  
Renshaw Cells ◽  
Spinal Interneurones

Properties of Renshaw cells excited by recurrent collaterals of pudendal motoneurons in the cat

2009 ◽  
Vol 65 ◽  
pp. S167
Author(s):  
Ken Muramatsu ◽  
Masatoshi Niwa ◽  
Kenji Sato ◽  
Sei-Ichi Sasaki
Keyword(s):  
Renshaw Cells ◽  
Recurrent Collaterals

Role of lateral hypothalamus on fluid, electrolyte, and cardiovascular responses to activation of the MSA

1994 ◽  
Vol 266 (2) ◽  
pp. R496-R502 ◽  
Author(s):  
A. S. Haibara ◽  
W. A. Saad ◽  
J. V. Menani ◽  
L. A. Camargo ◽  
A. Renzi
Keyword(s):  
Water Intake ◽  
Lateral Hypothalamus ◽  
Cardiovascular Responses ◽  
Electrolytic Lesion ◽  
Opioid Agonist ◽  
Inhibitory Mechanisms ◽  
Pressor Responses ◽  
Medial Septal Area ◽  
Opiate Agonist

In this study we investigated the influence of electrolytic lesion or of opioid agonist injections into the lateral hypothalamus (LH) on the dipsogenic, natriuretic, kaliuretic, antidiuretic, pressor, and bradycardiac effects of cholinergic stimulation of the medial septal area (MSA) in rats. Sham- and LH-lesioned male Holtzman rats received a stainless steel cannula implanted into the LH. Other groups of rats had cannulas implanted simultaneously into the MSA and LH. Carbachol (2 nmol) injection into the MSA induced water intake, pressor, and bradycardic responses. LH lesion reduced all of these effects (1-3 and 15-18 days). Previous injection of synthetic opiate agonist, FK-33824 (100 ng), into the LH reduced the water intake, natriuresis, kaliuresis, and pressor responses induced by carbachol injected into the MSA. These data show that both electrolytic lesion or injection of an opiate agonist in the LH reduces the fluid-electrolyte and cardiovascular responses to cholinergic activation of the MSA. The involvement of LH with central excitatory and inhibitory mechanisms related to fluid-electrolytic and cardiovascular control is suggested.

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