The Effects of Cardioactive Drugs on the Performance of Cultured Foetal Hearts

S. R. ARMSTRONG; D. B. LONGMORE

doi:10.1038/243350a0

The Effects of Cardioactive Drugs on the Performance of Cultured Foetal Hearts

Nature ◽

10.1038/243350a0 ◽

1973 ◽

Vol 243 (5406) ◽

pp. 350-352 ◽

Cited By ~ 6

Author(s):

S. R. ARMSTRONG ◽

D. B. LONGMORE

Keyword(s):

Cardioactive Drugs

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Interaction of diclofenac and ketoprofen with cardioactive drugs in rats

European Journal of Drug Metabolism and Pharmacokinetics ◽

10.1007/bf03191378 ◽

2009 ◽

Vol 34 (1) ◽

pp. 11-17 ◽

Cited By ~ 1

Author(s):

V. Jakovljevic ◽

A. Sabo ◽

Z. Tomić ◽

B. Milijašević ◽

M. Popovic ◽

...

Keyword(s):

Cardioactive Drugs

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Effects of cardioactive drugs on the beating activity of myocardial cell cultures isolated from offspring of trained and untrained pregant rats

In Vitro ◽

10.1007/bf02619612 ◽

1984 ◽

Vol 20 (8) ◽

pp. 629-634 ◽

Cited By ~ 5

Author(s):

A. W. Butler ◽

R. P. Farrar ◽

D. Acosta

Keyword(s):

Cell Cultures ◽

Myocardial Cell ◽

Cardioactive Drugs ◽

Myocardial Cell Cultures

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In vitro compatibility of various cardioactive drugs during simulated Y-site administration

European Journal of Hospital Pharmacy ◽

10.1136/ejhpharm-2012-000239 ◽

2013 ◽

Vol 20 (2) ◽

pp. 110-116 ◽

Cited By ~ 2

Author(s):

Valia Humbert-Delaloye ◽

Markoulina Berger-Gryllaki ◽

Pierre Voirol ◽

Laurent Gattlen ◽

André Pannatier

Keyword(s):

Cardioactive Drugs

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Measurement of Cardioactive Drugs in Biological Samples by HPLC

Journal of Liquid Chromatography ◽

10.1080/01483918808068362 ◽

1988 ◽

Vol 11 (5) ◽

pp. 1015-1040 ◽

Cited By ~ 10

Author(s):

R. J. Flanagan ◽

R. K. Bhamra ◽

S. Walker ◽

S. C. Monkman ◽

D. W. Holt

Keyword(s):

Biological Samples ◽

Cardioactive Drugs

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Saponins, cardioactive drugs and other steroids

Trease and Evans' Pharmacognosy ◽

10.1016/b978-0-7020-2933-2.00023-x ◽

2009 ◽

pp. 304-332

Author(s):

William Charles Evans ◽

Daphne Evans

Keyword(s):

Cardioactive Drugs

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The Isolated Mouse Atria as a New Model for Testing Cardioactive Drugs with Special Reference to Doxorubicin (Adriamycin®)

Pharmacology & Toxicology ◽

10.1111/j.1600-0773.1990.tb00751.x ◽

1990 ◽

Vol 66 (4) ◽

pp. 299-302 ◽

Cited By ~ 5

Author(s):

K. Hermansen ◽

I. M. N. Rasmussen ◽

H. S. Schou

Keyword(s):

Special Reference ◽

New Model ◽

Cardioactive Drugs

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INTERACTIONS BETWEEN CARDIOACTIVE DRUGS AND ANTIDEPRESSANTS

InPharma ◽

10.1007/bf03284492 ◽

1977 ◽

Vol 114 (1) ◽

pp. 17-17

Keyword(s):

Cardioactive Drugs

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Detection of takeoff potential from intracellular recordings

AJP Heart and Circulatory Physiology ◽

10.1152/ajpheart.1982.242.6.h1115 ◽

1982 ◽

Vol 242 (6) ◽

pp. H1115-H1117

Author(s):

R. McGillivray ◽

R. W. Wald

Keyword(s):

Electrical Stimulation ◽

Membrane Potential ◽

Action Potential ◽

Cardiac Action Potential ◽

Intracellular Recordings ◽

Purkinje Fibers ◽

Cardiac Action ◽

Cardiac Purkinje Fibers ◽

Cardioactive Drugs

The measurement of takeoff potential from intracellular recordings of the cardiac action potential may be useful in the study of the cardiac action potential may be useful in the study of spontaneous automaticity and of the effects of cardioactive drugs on active propagation. We describe a circuit capable of detecting and storing the membrane potential at a point where the slope of the membrane potential exceeds a preset value. The capability of this circuit to track the takeoff potential was tested using intracellular recordings from cardiac Purkinje fibers during spontaneous automaticity as well as during electrical stimulation.

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