SV40 Virus-induced Tumour Specific Transplantation Antigen in Cultured Mouse Cells

Nature ◽  
1970 ◽  
Vol 227 (5254) ◽  
pp. 141-145 ◽  
Author(s):  
RICHARD W. SMITH ◽  
JOEL MORGANROTH ◽  
PETER T. MORA
Keyword(s):  
Transplantation Antigen ◽  
Sv40 Virus ◽  
Mouse Cells

An embryo protein induced by SV40 virus transformation of mouse cells

Nature ◽  
1980 ◽  
Vol 288 (5792) ◽  
pp. 722-724 ◽  
Author(s):  
Peter T. Mora ◽  
K. Chandrasekaran ◽  
Vivian W. McFarland
Keyword(s):  
Sv40 Virus ◽  
Mouse Cells ◽  
Virus Transformation

Recovery of SV40 virus with genetic markers of original inducing virus from SV40-transformed mouse cells

Virology ◽  
1968 ◽  
Vol 35 (1) ◽  
pp. 1-8 ◽  
Author(s):  
K.K. Takemoto ◽  
G.J. Todaro ◽  
K. Habel
Keyword(s):  
Genetic Markers ◽  
Sv40 Virus ◽  
Mouse Cells

Some Structural Features of Metaphase Chromosomes of Mice and Men

1967 ◽  
Vol 25 ◽  
pp. 190-191
Author(s):  
Godfrey C. Hoskins ◽  
Betty B. Hoskins
Keyword(s):  
Electron Microscopy ◽  
Electron Micrographs ◽  
Structural Features ◽  
Metaphase Chromosomes ◽  
The Future ◽  
Of Mice And Men ◽  
Mouse Cells ◽  
Human And Mouse

Metaphase chromosomes from human and mouse cells in vitro are isolated by micrurgy, fixed, and placed on grids for electron microscopy. Interpretations of electron micrographs by current methods indicate the following structural features.Chromosomal spindle fibrils about 200Å thick form fascicles about 600Å thick, wrapped by dense spiraling fibrils (DSF) less than 100Å thick as they near the kinomere. Such a fascicle joins the future daughter kinomere of each metaphase chromatid with those of adjacent non-homologous chromatids to either side. Thus, four fascicles (SF, 1-4) attach to each metaphase kinomere (K). It is thought that fascicles extend from the kinomere poleward, fray out to let chromosomal fibrils act as traction fibrils against polar fibrils, then regroup to join the adjacent kinomere.

Human Adenovirus Uptake by Preirnplantation Mouse Embryos

1972 ◽  
Vol 30 ◽  
pp. 268-269
Author(s):  
D. G. Chase ◽  
W. Winters ◽  
L. Piko
Keyword(s):  
Hela Cells ◽  
Human Adenovirus ◽  
Mouse Embryos ◽  
Equilibrium Density ◽  
Cell Stage ◽  
Virus Attachment ◽  
Preimplantation Mouse Embryos ◽  
Embryo Culture Medium ◽  
Preimplantation Mouse ◽  
Mouse Cells

Although the outlines of human adenovirus entry and uncoating in HeLa cells has been clarified in recent electron microscope studies, several details remain unclear or controversial. Furthermore, morphological features of early interactions of human adenovirus with non-permissive mouse cells have not been extensively documented. In the course of studies on the effects of human adenoviruses type 5 (AD-5) and type 12 on cultured preimplantation mouse embryos we have examined virus attachment, entry and uncoating. Here we present the ultrastructural findings for AD-5.AD-5 was grown in HeLa cells and purified by successive velocity gradient and equilibrium density gradient centrifugations in CsCl. After dialysis against PBS, virus was sedimented and resuspended in embryo culture medium. Embryos were placed in culture at the 2-cell stage in Brinster's medium.

Sign in / Sign up

Export Citation Format

Share Document